Results 41 to 50 of about 1,367 (154)

Multispectral optoacoustic tomography of the human intestine – temporal precision and the influence of postprandial gastrointestinal blood flow

Photoacoustics, 2023
Multispectral optoacoustic tomography (MSOT) holds great promise as a non-invasive diagnostic tool for inflammatory bowel diseases. Yet, reliability and the impact of physiological processes during fasting and after food intake on optoacoustic signals ...
Lars-Philip Paulus, Alexandra L. Wagner, Adrian Buehler, Roman Raming, Jörg Jüngert, David Simon, Koray Tascilar, Alexander Schnell, Josefine Günther, Ulrich Rother, Werner Lang, André Hoerning, Georg Schett, Markus F. Neurath, Joachim Woelfle, Maximilian J. Waldner, Ferdinand Knieling, Adrian P. Regensburger   +17 more
doaj   +1 more source

Multispectral optoacoustic tomography (MSOT) scanner for whole-body small animal imaging

Optics Express, 2009
A major difficulty arising from whole-body optoacoustic imaging is the long acquisition times associated with recording signals from multiple spatial projections. The acquired signals are also generally weak and the signal-to-noise-ratio is low, problems often solved by signal averaging, which complicates acquisition and increases acquisition times to ...
Rui, Ma, Adrian, Taruttis, Vasilis, Ntziachristos, Daniel, Razansky   +3 more
openaire   +2 more sources

Imaging increased metabolism in the spinal cord in mice after middle cerebral artery occlusion

Photoacoustics, 2023
Emerging evidence indicates crosstalk between the brain and hematopoietic system following cerebral ischemia. Here, we investigated metabolism and oxygenation in the spleen and spinal cord in a transient middle cerebral artery occlusion (tMCAO) model ...
Ruiqing Ni, Nadja Straumann, Serana Fazio, Xose Luis Dean-Ben, Georgios Louloudis, Claudia Keller, Daniel Razansky, Simon Ametamey, Linjing Mu, César Nombela-Arrieta, Jan Klohs   +10 more
doaj   +1 more source

Multiscale four‐dimensional imaging of cardiac remodelling after myocardial infarction

The Journal of Physiology, EarlyView.
Abstract figure legend Multiscale 4D imaging framework for integrated phenotyping of post‐infarction remodelling. Myocardial infarction triggers dynamic changes across mechanical, haemodynamic and biological axes, progressing from acute injury and inflammation to extracellular matrix remodelling and scar maturation.
Hanzhou Lei, Boris Martinac, Yang Guo
wiley   +1 more source

A Novel IDO1/NE Dual Inhibitor, IMM‐H018 Prevents the Primary and Secondary Sepsis and Ameliorates the Kidney Injury Through Inhibiting the Cytokine Storm and Microthrombosis, and Reversing Immunosuppression

Advanced Science, Volume 13, Issue 55, 5 October 2026.
IMM‐H018, a dual IDO1/NE inhibitor, demonstrates potent therapeutic efficacy in sepsis by simultaneously targeting excessive inflammation and immune dysfunction. It prevents both primary and secondary sepsis through anti‐inflammatory, immune‐restoring, and renoprotective mechanisms, reducing organ damage, improving immune homeostasis, preserving kidney
Yi Zhou, Xiaodi Zhao, Xiaochen Pan, Zhiling Ma, Huaqing Cui, Hui Wen, Peng Wang, Xiufeng Liao, Kejie Qin, Yuchen Wang, Li Sheng, Sen Zhang   +11 more
wiley   +1 more source

Surface‐Enhanced Raman Scattering‐Based Multimodal Medical Imaging in Cancer Diagnosis and Therapy Monitoring

Rare Metals, Volume 45, Issue 10, October 2026.
ABSTRACT Surface‐enhanced Raman scattering (SERS) has emerged as a highly sensitive and specific technique for tumor imaging, owing to its narrow spectral features, resistance to photobleaching, and capability for multiplexed detection. However, its clinical translation remains limited by poor tissue penetration and the absence of intrinsic anatomical ...
Xinyu Miao, Yujiao Xie, Aochi Liu, Shishuai Zheng, Dong Xu, Aiguo Wu, Jie Lin, Xiaoxia Wu   +7 more
wiley   +1 more source

Detection of intramyocardially injected DiR-labeled mesenchymal stem cells by optical and optoacoustic tomography

Photoacoustics, 2017
The distribution of intramyocardially injected rabbit MSCs, labeled with the near-infrared dye 1,1′-dioctadecyl-3,3,3′,3′-tetramethylindotricarbo-cyanine-iodide (DiR) using hybrid Fluorescence Molecular Tomography-X-ray Computed Tomography (FMT-XCT) and ...
Markus T. Berninger, Pouyan Mohajerani, Moritz Wildgruber, Nicolas Beziere, Melanie A. Kimm, Xiaopeng Ma, Bernhard Haller, Megan J. Fleming, Stephan Vogt, Martina Anton, Andreas B. Imhoff, Vasilis Ntziachristos, Reinhard Meier, Tobias D. Henning   +13 more
doaj   +1 more source

Longitudinal Assessment of Muscle Involvement in Late‐Onset Pompe Disease Using Quantitative MRI: A Prospective Cohort Study

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.
ABSTRACT Background Late‐onset Pompe disease (LOPD) is a progressive metabolic myopathy characterised by lysosomal glycogen accumulation and leading to secondary disruptions in autophagy and cellular energy metabolism. While enzyme replacement therapy (ERT) has improved outcomes, early detection remains critical, because irreversible muscle damage ...
Alice De Lorenzo, Johannes Forsting, Martijn Froeling, Anne‐Katrin Güttsches, Elena Enax‐Krumova, Felix Kleefeld, Menekse Öztürk, Ferdinand Knieling, Matthias Vorgerd, Robert Rehmann, Tobias Ruck, Lara Schlaffke   +11 more
wiley   +1 more source

Multispectral optoacoustic tomography might be a helpful tool for noninvasive early diagnosis of psoriatic arthritis

Photoacoustics, 2021
Currently used imaging methods for diagnosis of psoriatic arthritis (PsA) frequently come along with exposure to radiation and can often only show long-term effects of the disease.
Sandra Hallasch, Nina Giese, Ingo Stoffels, Joachim Klode, Wiebke Sondermann   +4 more
doaj   +1 more source

Early Radiation Therapy Response Assessment Using Multi‐Scale Photoacoustic Imaging

Advanced Science, Volume 13, Issue 26, 8 May 2026.
Tomographic and mesoscopic photoacoustics capture intratumoural features of radioresistance and response. ABSTRACT There is a critical unmet clinical need to identify biomarkers that predict and detect radiation therapy (RT) response in cancer. Using the unique capabilities of multi‐scale photoacoustic imaging (PAI) to depict tumor oxygenation and ...
Thierry L. Lefebvre, Mariam‐Eleni Oraiopoulou, Ellie V. Bunce, Thomas R. Else, Lorna C. Wright, Monika A. Golinska, Lina Hacker, Cara Brodie, Steven Kupczak, Yi Cheng, Lisa Young, Paul W. Sweeney, Sarah E. Bohndiek   +12 more
wiley   +1 more source