Results 21 to 30 of about 1,367 (154)

Multispectral optoacoustic tomography for the non-invasive identification of patients with severe anemia in vivo

open access: yesPhotoacoustics, 2022
The immediate diagnosis of severe anemia is crucial for patient outcome. However, reliable non-invasive point-of-care diagnostic tools for e.g., ICU monitoring are currently lacking. Using an advanced Multispectral Optoacoustic Tomography (MSOT) research
Ingo Ganzleben   +6 more
doaj   +1 more source

Optoacoustic-Guided Magnetic Microrobot Platform for Precision Drug Delivery. [PDF]

open access: yesAdv Mater
Optoacoustically guided FePt@ZIF‐8‐based microrobots are designed with high drug loading capacity, controllable locomotion, and deep‐tissue imaging capability. By integrating navigation, drug release, and real‐time monitoring into a single platform, they provide a versatile tool for precise intervention, opening new possibilities for treating ...
Wang F   +12 more
europepmc   +2 more sources

Evaluation of Tracheal Stenosis in Rabbits Using Multispectral Optoacoustic Tomography

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Objective: Photoacoustic tomography (PAT) and multispectral optoacoustic tomography (MSOT) are evolving technologies that are capable of delivering real-time, high-resolution images of tissues. The purpose of this study was to evaluate the feasibility of
Yanting Wen   +12 more
doaj   +1 more source

In Vivo Immunoscoring Technique to Monitor Anti‐CD47 Immunotherapy Efficacy in Triple‐Negative Breast Cancer [PDF]

open access: yesCancer Med
Intravital imaging using MCP1‐FITC and dextran‐AF680 assesses macrophage targeting and polarization in murine 4T1 tumor models. Visualization of M1‐like and M2‐like macrophages and M1/M2 ratio quantification support evaluation of anti‐CD47 immunotherapy, highlighting the potential of macrophage‐targeted imaging for patient stratification and treatment ...
Yang M   +6 more
europepmc   +2 more sources

Dynamic 2-deoxy-D-glucose-enhanced multispectral optoacoustic tomography for assessing metabolism and vascular hemodynamics of breast cancer

open access: yesPhotoacoustics, 2023
Clinical tools for measuring tumor vascular hemodynamics, such as dynamic contrast-enhanced MRI, are clinically important to assess tumor properties. Here we explored the use of multispectral optoacoustic tomography (MSOT), which has a high spatial and ...
Zheng Han   +10 more
doaj   +1 more source

Spatial quantification of clinical biomarker pharmacokinetics through deep learning-based segmentation and signal-oriented analysis of MSOT data

open access: yesPhotoacoustics, 2022
Although multispectral optoacoustic tomography (MSOT) significantly evolved over the last several years, there is a lack of quantitative methods for analysing this type of image data.
Bianca Hoffmann   +7 more
doaj   +1 more source

Non-invasive multispectral optoacoustic tomography resolves intrahepatic lipids in patients with hepatic steatosis

open access: yesPhotoacoustics, 2023
Hepatic steatosis is characterized by intrahepatic lipid accumulation and may lead to irreversible liver damage if untreated. Here, we investigate whether multispectral optoacoustic tomography (MSOT) can offer label-free detection of liver lipid content ...
Nikolina-Alexia Fasoula   +15 more
doaj   +1 more source

Functional multispectral optoacoustic tomography imaging of hepatic steatosis development in mice

open access: yesEMBO Molecular Medicine, 2021
The increasing worldwide prevalence of obesity, fatty liver diseases and the emerging understanding of the important roles lipids play in various other diseases is generating significant interest in lipid research.
Shan Huang   +7 more
doaj   +1 more source

Multispectral optoacoustic tomography for non-invasive disease phenotyping in pediatric spinal muscular atrophy patients

open access: yesPhotoacoustics, 2022
Proximal spinal muscular atrophy (SMA) is a rare progressive, life limiting genetic motor neuron disease. While promising causal therapies are available, meaningful prognostic biomarkers for therapeutic monitoring are missing.
Adrian P. Regensburger   +14 more
doaj   +1 more source

Current and Emerging Clinical Applications of Multispectral Optoacoustic Tomography (MSOT) in Oncology [PDF]

open access: yesClinical Cancer Research, 2016
Abstract Accurate detection and characterization of cancers are key for providing timely intervention and effective treatments. Current imaging technologies are particularly limited when it comes to detecting very small tumors in vivo, i.e., very early cancers or metastases, differentiating viable tumor from surrounding dead tumor tissue,
Lacey R, McNally   +6 more
openaire   +2 more sources

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