Water, Collagen, and Lipid Content in the Human Skin and Muscles Assessed with Near‐Infrared Diffuse Reflectance Spectroscopy and Multi‐Spectral Optoacoustic Tomography [PDF]
Advanced ScienceInfrared spectroscopy can quantify individual body components such as lipids, water, and proteins, but extending it to a comprehensive assessment of overall body composition is hampered by high variability and optical heterogeneity of biological tissues.
Denis Davydov +9 more
doaj +3 more sources
Optoacoustic imaging of the brain in a cachexia-inducing pancreatic cancer xenograft [PDF]
Frontiers in OncologyPancreatic cancer-induced cachexia drives co-morbidities that result in a poor quality of life. To expand understanding of the effects of cachexia on the brain here, for the first time, we used noninvasive oxygen enhanced (OE) multispectral optoacoustic ...
Saleem Yousf +10 more
doaj +2 more sources
Multi-wavelength graph convolutional network for high-performance sparse multispectral optoacoustic tomography [PDF]
PhotoacousticsThe rapid advancement of multispectral optoacoustic tomography (MSOT) has developed for label-free biomedical imaging by providing anatomical and functional visualization through multi-wavelength laser excitation and ultrasound detection.
Mengyang Lu +4 more
doaj +2 more sources
Multispectral Opto-acoustic Tomography (MSOT) of the Brain and Glioblastoma Characterization
NeuroImage, 2013 Brain research depends strongly on imaging for assessing function and disease in vivo. We examine herein multispectral opto-acoustic tomography (MSOT), a novel technology for high-resolution molecular imaging deep inside tissues. MSOT illuminates tissue with light pulses at multiple wavelengths and detects the acoustic waves generated by the ...
Stefan Morscher +2 more
exaly +3 more sources
Derivation and validation of a non-invasive optoacoustic imaging biomarker for detection of patients with intermittent claudication [PDF]
Communications MedicineBackground Peripheral arterial disease (PAD) affects more than 200 million people worldwide, with symptoms ranging from none to severe. Despite these different diagnostic options, patients with unclear leg pain remain challenging to diagnose. The primary
Milenko Caranovic +19 more
doaj +2 more sources
Multispectral optoacoustic tomography of benign parotid tumors in vivo: a prospective observational pilot study [PDF]
Scientific ReportsParotid lumps are a heterogeneous group of mainly benign but also malignant tumors. Preoperative imaging does not allow a differentiation between tumor types. Multispectral optoacoustic tomography (MSOT) may improve the preoperative diagnostics.
Mussab Kouka +2 more
doaj +2 more sources
Optoacoustic imaging in lower extremity revascularization: A novel technique to assess perioperative muscle perfusion [PDF]
PhotoacousticsObjectives: This proof-of-concept study aimed to assess the feasibility of Multispectral Optoacoustic Tomography (MSOT) in evaluating changes in oxygenated hemoglobin (HbO2) levels in muscles of the lower limb before and after lower extremity ...
Tim Wittig +5 more
doaj +2 more sources
Photoacoustics, 2014 A common side effect of medication is gastrointestinal intolerance. Symptoms can include reduced appetite, diarrhea, constipation, GI inflammation, nausea and vomiting. Such effects often have a dramatic impact on compliance with a treatment regimen. Therefore, characterization of GI tolerance is an important step when establishing a novel therapeutic ...
Stefan Morscher
exaly +3 more sources
Application of multispectral optoacoustic tomography for lower limb musculoskeletal sports injuries in adults [PDF]
PhotoacousticsCompositional changes in relation to musculoskeletal injuries are difficult to measure non-invasively. This study aims to use non-invasive label-free imaging with Multispectral Optoacoustic Tomography (MSOT) to evaluate compositional changes with injury.
Rene B. Svensson +9 more
doaj +2 more sources
Theranostics, 2018 Objective: Monitoring emerging vascular-targeted photodynamic therapy (VTP) and understanding the time-dynamics of treatment effects remains challenging. We interrogated whether handheld multispectral optoacoustic tomography (MSOT) could noninvasively monitor the effect of VTP using WST11, a vascular-acting photosensitizer, on tumor tissues over time ...
Kwanghee Kim +2 more
exaly +4 more sources