Results 111 to 120 of about 13,446 (217)
Improving Melatonin Delivery Within the Eye [PDF]
, 2017 Melatonin is a neurohormone synthesized in the pineal gland as well as in other organs and it plays an important role in many ocular functions, as it is synthesized in numerous eye structures.
Alkozi, Hanan Awad, Pintor, Jesús
core +2 more sources
Neurobiology of Disease, 2017 Recent studies about the novel antidepressant agomelatine, which is a mixed MT1 and MT2 melatonin receptor agonist and 5HT2C serotonin receptor antagonist possessing an anticonvulsant and neuroprotective action, suggest that it may have potential to ...
Jana Tchekalarova +6 more
doaj +1 more source
Pharmacology Research & Perspectives, 2020 Melatonin is a neurohormone that translates the circadian rhythm to the peripheral organs through a series of binding sites identified as G protein‐coupled receptors MT1 and MT2.
Céline Legros +10 more
doaj +1 more source
Foxp2 controls synaptic wiring of corticostriatal circuits and vocal communication by opposing Mef2c [PDF]
, 2016 Cortico-basal ganglia circuits are critical for speech and language and are implicated in autism spectrum disorder, in which language function can be severely affected.
A Di Martino +64 more
core +2 more sources
Ultrastructural evidence of a secretory role for melatonin in the human parotid gland [PDF]
, 2015 In vivo animal studies show that pentagastrin, cholecystokinin and melatonin cause the secretion and synthesis of salivary proteins. Melatonin occurs in large amounts in the gut and is released into the blood on food intake.
Ekstrom, J. +6 more
core
The role of the mammalian prion protein in the control of sleep [PDF]
, 2017 Sleep disruption is a prevalent clinical feature in many neurodegenerative disorders, including human prion diseases where it can be the defining dysfunction, as in the case of the “eponymous” fatal familial insomnia, or an early-stage symptom as in ...
Gill, Andrew C., Roguski, Amber
core +2 more sources
Melatonin MT1 and MT2 receptor expression in Parkinson's disease.
Medical science monitor : international medical journal of experimental and clinical research, 2010 Idiopathic Parkinson disease (PD) is a multi-system disorder with a multifactorial etiology and diverse clinical phenotype. Selective, regional dopaminergic neuronal degeneration in the substantia nigra and other CNS areas including the amygdala are observed in all patients.
Nikhil, Adi +5 more
openaire +1 more source
The role of melatonergic system in intervertebral disc degeneration and its association with low back pain: a clinical study [PDF]
PeerJObjective The mechanisms of intervertebral disc degeneration (IVDD) in low back pain (LBP) patients are multiples. In this study, we attempt to investigate whether melatonergic system plays a potential role in IVDD patients with LBP by analyzing their ...
Chong Chen +10 more
doaj +2 more sources
Dianas terapéuticas de melatonina: propiedades y beneficios [PDF]
, 2018 La melatonina ( N - Acetil - 5 - metoxitriptamina ) es una hormona indólica derivada del triptófano, cuya producción ocurre principalmente en la glándula pineal. Está implicada en una gran cantidad de procesos biológicos pero su
Cid Galván, Nerea
core