Results 101 to 110 of about 13,446 (217)
Melatonin regulates the aging mouse hippocampal homeostasis via the sirtuin1-FOXO1 pathway [PDF]
Sirtuin1 (SIRT1) and forkhead box transcription factor O subfamily 1 (FOXO1) play vital roles in the maintenance of hippocampal neuronal homeostasis during aging. Our previous study showed that melatonin, a hormone mainly secreted by the pineal gland,
Boontem, Parichart +5 more
core +1 more source
Comment développer un antidépresseur au mécanisme d’action innovant : l’exemple de l’agomélatine [PDF]
, 2005 Divers axes de recherche ont été suivis pour obtenir de nouveaux traitements de la dépression plus efficaces, mieux tolérés et d’action plus rapide. Parmi ces axes de recherche, la mélatonine, synchronisateur endogène des rythmes biologiques chez les ...
Boyer, Pierre-Alain +3 more
core +1 more source
The FASEB Journal, Volume 40, Issue 8, 30 April 2026.An overlap between proteomic and transcriptomic findings in experiments testing brain responses to glucocorticoids. A shows that 455 proteins responsive to glucocorticoids were not confirmed at the transcriptomic level while 4 proteins were matched with significant differences in mRNA in all 8 datasets derived from transcriptomic experiments.
Grzegorz R. Juszczak
wiley +1 more source
Melatonin receptor depletion suppressed hCG-induced testosterone expression in mouse Leydig cells
Cellular & Molecular Biology Letters, 2019 Melatonin receptors MT1 and MT2 (genes officially named MTNR1A and MTNR1B, respectively) play crucial roles in melatonin-mediated regulation of circadian rhythms, the immune system, and control of reproduction in seasonally breeding animals.
Yuan Gao +9 more
doaj +1 more source
Metallothioneins 1 and 2, but not 3, are regulated by nutritional status in rat white adipose tissue [PDF]
, 2016 The influence of fasting or fasting/refeeding on: MT2 and MT3 mRNA level relative to β-actin expression in WAT of rats.
Aleksandra Bielicka-Gieldon +5 more
core +3 more sources
Brain and Behavior, Volume 16, Issue 4, April 2026.Melatonin rescues the cognitive deficits induced by gestational intermittent hypoxia exposure in male offspring mice, and these results were associated with neuroinflammation, BBB integrity, and alterations in synaptic function. ABSTRACT Introduction Gestational intermittent hypoxia (GIH), which serves as a model for obstructive sleep apnea (OSA), is ...
Xue‐Yan Li +6 more
wiley +1 more source
Melatonergic Signaling Sustains Food Allergy Through FcεRI Recycling
ResearchThe prevalence of food allergies is increasing dramatically and causing serious public health concerns. Notably, melatonin metabolism imbalance in patients with food allergies; however, the role of melatonin in food allergies remains unclear.
Youxia Wang +6 more
doaj +1 more source
Gamete signalling underlies the evolution of mating types and their number [PDF]
, 2016 Predictions about the evolution of sex determination mechanisms have mainly focused on animals and plants, whereas unicellular eukaryotes such as fungi and ciliates have received little attention.
hadjivasiliou, Z, Pomiankowski, A
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Essential metals at the host-pathogen interface : nutritional immunity and micronutrient assimilation by human fungal pathogens [PDF]
, 2015 AC and DW are supported by a Sir Henry Dale Fellowship jointly funded by the Wellcome Trust and the Royal Society (Grant Number 102549/Z/13/Z).Peer reviewedPublisher ...
Crawford, Aaron, Wilson, Duncan
core +1 more source
Medical Journal of Dr. D.Y. Patil Vidyapeeth, 2019 Concerning Agomelatine, as of this present moment and deeply analyzing things from the psychopharmacological point of view, the utmost important question yet to be answered is “why should the drug Agomelatine be regarded as an antidepressant agent when ...
Olumuyiwa John Fasipe +3 more
doaj +1 more source