Results 151 to 160 of about 120,377 (263)

Mitochondrial DNA mutations are associated with impaired oxidative phosphorylation and enhanced imatinib response in chronic myeloid leukemia. [PDF]

Hemasphere
Pagani IS, Krishnan V, Ouyang JF, Kok CH, Chen B, Lee KL, Pham CM, Wang P, Page E, Dang P, Saunders VA, James J, Lim K, Mangiola S, Gao Y, Shanmuganathan N, Yong A, Branford S, Chuah C, Yeung DT, White DL, Helgason VG, Thomas D, Ong ST, Hughes TP, Ross DM.   +25 more
europepmc   +1 more source

Involvement of the Endocrine System is Common in Mitochondrial Disorders and Requires Long-term Comprehensive Investigations

JCRPE
Josef Finsterer
doaj   +1 more source

Leptin attenuates heat stress-induced mitoxyperilysis in porcine Sertoli cells by suppressing the mtDNA-cGAS-STING axis. [PDF]

J Anim Sci Biotechnol
Guo M, Zhang J, Gu S, Gao Y, Zhu Z, Zhang T, Lu H, Luo J, Zeng W.   +8 more
europepmc   +1 more source

Is DNA metabarcoding an option for formaldehyde‐preserved zooplankton time series?

Limnology and Oceanography: Methods, EarlyView.
Abstract The recovery of amplifiable DNA from formaldehyde‐fixed (FF) zooplankton samples has long been considered problematic, but advances in degraded‐DNA retrieval have renewed interest in FF samples. To access the information stored in long‐term zooplankton time series, we evaluated methods for extracting amplifiable DNA from community samples ...
Aitor Albaina, Anders Lanzén, Irati Miguel, Fernando Rendo, María Santos   +4 more
wiley   +1 more source

Mitochondrial homeostasis and aging: the mtDNA-cGAS-STING axis. [PDF]

Front Immunol
Wang L, Zhang Z, Xia B, Li J, You H.
europepmc   +1 more source

Toxicity Differences Between Microplastics and Nanoplastics in Organs: From Molecular Mechanisms to Potential Therapeutic Strategies

Med Research, EarlyView.
This review systematically compares the size‐dependent toxicity of microplastics and nanoplastics in the intestine, liver, kidney, lung, and brain. Particle size determines bioavailability, barrier penetration, and injury mechanisms. Because of their small size and high surface reactivity, NPs readily cross the intestinal epithelium and blood–brain ...
Yixian Cheng, Junjie Chen, Rui Fu, Jiawei Zhang, Jianguang Jia, Wei Wang, Zheng Zhang, Peng Zhang, Haosong Chen, Huake Cao, Gang Li, Weiwei Sheng, Ting Li, Bo Chen, Guodong Cao   +14 more
wiley   +1 more source

Multilayered interplay between the cGAS-STING pathway and autophagy. [PDF]

Autophagy Rep
Huang Z, Gao X, Lin J, Feng D, Lu G.
europepmc   +1 more source

The role of tryptophan hydroxylase‐1 in metabolic dysfunction‐associated steatotic liver disease

Pediatric Investigation, EarlyView.
Silencing hepatic tryptophan hydroxylase 1 (TPH1) alleviated diet‐induced steatotic liver disease by reducing lipid accumulation, oxidative stress, inflammation, fibrosis, and hepatocyte apoptosis. These protective effects were mediated, at least in part, through restoration of Parkin‐dependent mitochondrial autophagy, identifying hepatic TPH1 as a ...
Shuangzhen Jia, Xiaolin Ye, Zhaoxia Wang, Jie Wu   +3 more
wiley   +1 more source

Clonal Mosaicism of Mitochondrial DNA Heteroplasmy as a Molecular Clock of Aging. [PDF]

Aging Cell
Chang R, Tsai AP, Wang B, Tsui KH, Pang CY, Li CJ.   +5 more
europepmc   +1 more source

Needle in a haystack: Holocene history of European larch in Central Europe revisited

PLANTS, PEOPLE, PLANET, EarlyView.
Defining nativity of species is crucial for their management. However, this is a complex task, especially for species that have been used and spread by humans for a long time. We combined paleoecological records with extensive genetic data to investigate the Holocene history of European larch—a common and economically important tree species in Central ...
Martin Prach, Petr Pokorný, Kristýna Hošková, Daniel Vondrák, Pavel Bednář, Jindřich Prach, Jana Hanzal Šedivá, Hana Drahošová, Kateřina Podrábská, Přemysl Bobek, Jan Smyčka, Tomáš Fér   +11 more
wiley   +1 more source