Results 161 to 170 of about 72,894 (246)

Mitochondrial DNA breaks and copy number and the risk of lung cancer in the Shanghai Women's Health Study. [PDF]

Cancer Epidemiol Biomarkers Prev
Blechter B, Shu XO, Hu W, Francis ER, Zheng W, Cai Q, Cai H, Yang G, Hosgood HD, Cawthon RM, Lan Q.   +10 more
europepmc   +1 more source

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter, I. M. Adcock, C. Benito‐Villalvilla, R. Bianchini, L. Bjermer, G. Caramori, L. Cari, K. F. Chung, Z. Diamant, I. Eguiluz‐Gracia, E. F. Knol, M. Jesenak, F. Levi‐Schaffer, G. Nocentini, L. O'Mahony, O. Palomares, F. Redegeld, M. Sokolowska, B. Van Esch, M. Zurlo, C. Stellato   +20 more
wiley   +1 more source

Expanding the landscape of tRNA pathogenic variants in mitochondrial DNA. [PDF]

Brain Commun
Siragusa SL, Blando S, Fiorini C, Pasti AP, Ormanbekova D, Casadei F, Morandi L, Pegoraro E, Liguori R, Carelli V, La Morgia C, Caporali L, Valentino ML.   +12 more
europepmc   +1 more source

Sperm Mitochondrial DNA Copy Number and Nuclear DNA Methylation Across Clinical and Non‐Clinical Preconception Cohorts

Andrology, EarlyView.
ABSTRACT Background Sperm mitochondrial DNA copy number is an emerging marker of male fertility, with elevated mtDNAcn associated with poor semen quality across various populations. Sperm DNA methylation has also been previously demonstrated to be negatively correlated with semen parameters in IVF cohorts.
Savni Sawant, Karolina Nowak, Amanda L. Paskavitz, Emily Houle, Ricardo P. Bertolla, Lidia Minguez‐Alarcon, Russ Hauser, J. Richard Pilsner   +7 more
wiley   +1 more source

Nuclear Transfer Perturbs Genomic Balance. [PDF]

Epigenomes
Andreas E, St John JC.
europepmc   +1 more source

Application of Multi‐Method Dating for Understanding the Gravettian North of Moravia, Central Europe

Archaeometry, EarlyView.
ABSTRACT This article presents the results of integrating three methods to assess the age of the Upper Palaeolithic site of Pietraszyn 11 (SW Poland), close to the Moravian Gate. Sediment chronology determined using optically stimulated luminescence produced promising, yet ambiguous results (51.0 ± 3.7 to 20.3 ± 0.7 ka).
A. Wiśniewski, B. Bujalska, D. Popović, M. Baca, K. Zarzecka‐Szubińska, A. Lemanik, M. Hein, S. Talamo, P. Moska, H. Fewlass, D. Tokarz, Z. Jary, B. Przybylski, D. Bobak, M. Połtowicz‐Bobak, K. Wertz, A. Nadachowski   +16 more
wiley   +1 more source

AI‐Assisted Morphometric Analysis and Molecular Phylogeny for a Dactylogyrid (Monopisthocotyla) Skin Parasite of an Ornamental Crenuchid Fish From Brazil

Acta Zoologica, EarlyView.
ABSTRACT This study presents a formal description and taxonomic appraisal of Cacatuocotyle adrianoi sp. n., a Neotropical parasite belonging to the family Dactylogyridae, integrating AI‐assisted morphometric analyses, molecular data, and phylogenetic reconstruction. Phylogenetic analyses recovered Cacatuocotyle adrianoi sp. n.
J. C. C. Aguiar, M. M. Osaki‐Pereira, N. G. Silva, P. D. Mathews, R. J. Silva   +4 more
wiley   +1 more source

Icariin attenuates diabetic cardiomyopathy by inhibiting NLRP3 inflammasome through SIRT3-mediated TFAM deacetylation. [PDF]

Front Pharmacol
Sun M, Huang H, Wei C, Xing Y, Wu B.
europepmc   +1 more source

Out in the cold? A review of Early Middle Palaeolithic settlements in northern Central Europe, age data and geological preconditions for site formation and preservation

Boreas, EarlyView.
The characteristics of settlement of Neanderthals in northern Central Europe during the earlier phases of the Middle Palaeolithic (Marine Isotope Stage 8–6) have been a matter of debate for decades, specifically regarding the population dynamics at such latitudes during the coldest phases. In this paper, we review the known archaeological record of the
Gianpiero Di Maida, Jutta Winsemann, Malte Hoffmann, Tobias Lauer, Utz Böhner, Thomas Terberger   +5 more
wiley   +1 more source

Modulation of mitochondrial DNA copy number: therapeutic potential of phytochemicals and plant extracts-a comprehensive review. [PDF]

Arch Pharm Res
Perri MR, Cerantonio A, Cipriani MG, Manna I, Aureli A, Marziani B, Andreozzi F, Mannino GC, Mancuso E, Averta C, Statti G, Citrigno L, Mainieri D.   +12 more
europepmc   +1 more source