Results 221 to 230 of about 123,318 (262)

From glacial echoes to timber pathways: Climatic–historical drivers and timber‐trade influence on the phylogeography of Ips sexdentatus in the Basque Country

Agricultural and Forest Entomology, EarlyView.
Ips sexdentatus is expanding across southern Europe, attacking multiple Pinus species and showing the ability to colonize trees at early stages of decline. Genetic analysis of 668 individuals revealed 106 haplotypes, with Iberian populations as diversity hotspots, reflecting long‐term refugial persistence alongside more recent demographic expansion ...
Dimitrios N. Avtzis, Nebai Mesanza, Aitor Saez de Zerain, Diego Llamazares, Eugenia Iturritxa   +4 more
wiley   +1 more source

The Origins of Allergy: An Outside‐In, Bioenergetic Hypothesis

Allergy, EarlyView.
ABSTRACT Allergic disease has risen too rapidly for inherited susceptibility to explain it, and the risk variants so far reported lie in the epithelial barrier and in type‐2 immunity. We propose a five‐layer model in which epithelial barrier and bioenergetic dysfunction may precede and promote type‐2 immune deviation rather than arise solely as its ...
Peter K. Smith, Nicholas P. West, Stanley Du Preez, Hugh A. Sampson, Peter W. Hellings, David Price, Liam O'Mahony, Carina Venter, Cezmi A. Akdis, Gil Yosipovitch   +9 more
wiley   +1 more source

Mitochondrial Genomic Alterations in Pediatric Acute Lymphoblastic Leukemia: Implications for Methotrexate-Induced Neurotoxicity and Ethnic Disparities. [PDF]

Cancer Med
Han J, Arsang-Jang S, Auer PL, Saber W, Michaelis L, Urrutia R, Gai X, Lupo P, Scheurer M, Dong J.   +9 more
europepmc   +1 more source

Sperm Mitochondrial DNA Copy Number and Nuclear DNA Methylation Across Clinical and Non‐Clinical Preconception Cohorts

Andrology, EarlyView.
ABSTRACT Background Sperm mitochondrial DNA copy number is an emerging marker of male fertility, with elevated mtDNAcn associated with poor semen quality across various populations. Sperm DNA methylation has also been previously demonstrated to be negatively correlated with semen parameters in IVF cohorts.
Savni Sawant, Karolina Nowak, Amanda L. Paskavitz, Emily Houle, Ricardo P. Bertolla, Lidia Minguez‐Alarcon, Russ Hauser, J. Richard Pilsner   +7 more
wiley   +1 more source

Leptin attenuates heat stress-induced mitoxyperilysis in porcine Sertoli cells by suppressing the mtDNA-cGAS-STING axis. [PDF]

J Anim Sci Biotechnol
Guo M, Zhang J, Gu S, Gao Y, Zhu Z, Zhang T, Lu H, Luo J, Zeng W.   +8 more
europepmc   +1 more source

AI‐Assisted Morphometric Analysis and Molecular Phylogeny for a Dactylogyrid (Monopisthocotyla) Skin Parasite of an Ornamental Crenuchid Fish From Brazil

Acta Zoologica, EarlyView.
ABSTRACT This study presents a formal description and taxonomic appraisal of Cacatuocotyle adrianoi sp. n., a Neotropical parasite belonging to the family Dactylogyridae, integrating AI‐assisted morphometric analyses, molecular data, and phylogenetic reconstruction. Phylogenetic analyses recovered Cacatuocotyle adrianoi sp. n.
J. C. C. Aguiar, M. M. Osaki‐Pereira, N. G. Silva, P. D. Mathews, R. J. Silva   +4 more
wiley   +1 more source

Mitochondrial retrograde signaling in gastric cancer: mtDNA mutations, ROS-driven NF-κB/HIF-1α activation, and Warburg effect amplification. [PDF]

Front Physiol
Bai Y, Chen W.
europepmc   +1 more source

Out in the cold? A review of Early Middle Palaeolithic settlements in northern Central Europe, age data and geological preconditions for site formation and preservation

Boreas, EarlyView.
The characteristics of settlement of Neanderthals in northern Central Europe during the earlier phases of the Middle Palaeolithic (Marine Isotope Stage 8–6) have been a matter of debate for decades, specifically regarding the population dynamics at such latitudes during the coldest phases. In this paper, we review the known archaeological record of the
Gianpiero Di Maida, Jutta Winsemann, Malte Hoffmann, Tobias Lauer, Utz Böhner, Thomas Terberger   +5 more
wiley   +1 more source