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A modified procedure for quantitative analysis of mtDNA, detecting mtDNA depletion [PDF]
Quantitative analysis of mitochondrial DNA (mtDNA) is crucial for proper diagnosis of diseases that are caused by or associated with mtDNA depletion. However, such a quantitative characterization of mtDNA is not a simple procedure and requires several laboratory steps at which potential errors can accumulate.
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‘Polynesian’ mtDNA in the Malagasy
Nature Genetics, 1995H, Soodyall, T, Jenkins, M, Stoneking
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