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Mitochondrial DNA damage in HIV infection: a mechanistic driver of immunometabolic dysfunction and chronic inflammation. [PDF]
Ma L, Wang X, Xu H.
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The mitogenome mutation repertoire affects progression of Parkinson's Disease. [PDF]
Matos GB +11 more
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Mitochondrial DNA Instability and Neuroinflammation: Connecting the Dots Between Base Excision Repair and Neurodegenerative Disease. [PDF]
Pittman MN +3 more
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Longitudinal Analysis of Mitochondrial D-Loop Methylation and Copy Number in Peripheral Blood: Epigenetic Signatures of Alzheimer's Disease Progression and Aging. [PDF]
Rizzo B +10 more
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The roles of the mtDNA-cGAS-STING axis in tumor immunity: from immune activation to immune evasion. [PDF]
Huang N, Liu Z, Lei H, Liu X.
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Proceedings of the Eleventh International Conference on Tangible, Embedded, and Embodied Interaction, 2017
Rapid growth in the volume of cancer DNA sequencing data has not been matched by an increase in our ability to understand, explore, and interpret this data. There is a need for new tools that can enhance analyses in order to enable us to interpret the data, discover new or unexpected information, and ultimately form insights. We present Tangible mtDNA,
Roozbeh Manshaei +5 more
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Rapid growth in the volume of cancer DNA sequencing data has not been matched by an increase in our ability to understand, explore, and interpret this data. There is a need for new tools that can enhance analyses in order to enable us to interpret the data, discover new or unexpected information, and ultimately form insights. We present Tangible mtDNA,
Roozbeh Manshaei +5 more
openaire +1 more source
Platelet mtDNA content and leukocyte count influence whole blood mtDNA content
Mitochondrion, 2020Changes in whole blood (WB) mitochondrial DNA (mtDNA) content are associated with health and disease. Platelet-derived mtDNA can confound WB mtDNA content measurements. From a sample of 44 volunteers, we show that platelet mtDNA content and platelet:leukocyte ratio are both dependent predictors of WB mtDNA content, but that platelet count itself is not.
Hanjoo B, Shim +4 more
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