Results 191 to 200 of about 320,721 (362)

[Xinfeng capsule inhibits immune inflammation in osteoarthritis by inhibiting the miR- 23a-3p/PETN/PI3K/AKT/mTOR pathway].

, 2021
Bingxi Bao, J Liu, L Wan, Y Zhang, Yan Long, Guangpan Sun   +5 more
openalex   +2 more sources

Targeting the mTOR and TRAIL Pathways in Multiple Myeloma. Resumen de tesis

, 2012
Extracto de tesis.[ES] Aunque hay varios estudios que destacan la activación de la vía PI3K/Akt en mieloma, hay menos información sobre el estado y el papel de la vía mTOR.
Chen, Xi
core  

Light‐Switched Mesenchymal Stem Cells for In Situ Exosome Amplification in Craniofacial Bone Defect Reconstruction

Advanced Science, EarlyView.
Light‐switchable MSCs (MSC‐UCNPs) were constructed by intracellular incorporation of UCNPs. Upon 980 nm irradiation, UCNPs emitted localized ultraviolet light (365 nm), activating the ROS/HEXB/LAMP1 signaling pathway to suppress lysosome–multivesicular body fusion and thereby enhance exosome biogenesis. Embedded within an injectable hydrogel, MSC‐UCNPs
Tingting Wu, Yajing Liu, Shuman Wang, Xiaoming Bai, Luyun Zhang, Yuwei Liu, Zhiwen Fu, Chen Shi   +7 more
wiley   +1 more source

Enhanced Antitumor Activity with Combining Effect of mTOR Inhibition and Microtubule Stabilization in Hepatocellular Carcinoma [PDF]

, 2013
Qian Zhou, Chi Hang Wong, Cecilia Pik Yuk Lau, Connie Wun Chun Hui, Vivian Wai Yan Lui, Stephen L. Chan, Winnie Yeo   +6 more
openalex   +1 more source

The Immune Imbalance of Treg/Th17 in Otitis Media of Effusion Patients May be Related to PI3K/Akt/mTOR Signaling Activation in the Middle Ear Mucosa

, 2021
Xianhai Zeng
openalex   +1 more source

mTOR Inhibitor-Corticoid Combination Therapy For Multiple Sclerosis

, 2018
The invention relates to a combination medicament for the treatment or therapy of multiple sclerosis, which comprises a corticosteroid and an inhibitor of mTOR.
Chan, Andrew, Hoepner, Robert
core  

Natural Resistance to Ovarian Hyperstimulation Syndrome in Estrildid Finches Reveals Macrophage GPR183 as a Potential Therapeutic Target

Advanced Science, EarlyView.
Ovarian macrophage depletion reverses OHSS resistance in estrildid finches and exacerbates OHSS symptoms in rats. Activating macrophage GPR183 alleviates OHSS by reducing pro‐inflammatory factors, increasing immunomodulatory molecules, remodeling CD44/SDC4‐mediated communication, and restoring immune homeostasis.
Xiaofei Yan, Yongjie Huang, Jiabao Yang, Su Ma, Songsong Liu, Xuan Huang, Juergen Brosius, Huaping Zheng, Bing Yao, Li Chen, Shanshan Lai, Cheng Deng   +11 more
wiley   +1 more source

Figure S2 from Colony-Stimulating Factor 1 Receptor (CSF1R) Activates AKT/mTOR Signaling and Promotes T-Cell Lymphoma Viability [PDF]

, 2023
Carlos Murga‐Zamalloa, Delphine Rolland, Avery Polk, Ashley Wolfe, Hiran Dewar, Pinki Chowdhury, Özlem Önder, Rajan Dewar, Noah A. Brown, Nathanael G. Bailey, Kedar Inamdar, Megan S. Lim, Kojo S.J. Elenitoba‐Johnson, Ryan A. Wilcox   +13 more
openalex   +1 more source

“Membrane‐Guided” Repair Strategy: Precision Delivery of GGT1 Degrader for Targeted Repair and Regeneration of Spinal Cord Neurons

Advanced Science, EarlyView.
This study confirms that GGT1 is a key driver of neuronal ferroptosis following spinal cord injury. We developed NSCm@EA, a biomimetic delivery system coated with neural stem cell membranes, for precise delivery of enocyanin to injured neurons. By combining targeted delivery with ubiquitination degradation mechanisms, this system promotes MGRN1 ...
Tao Yang, Lei Ye, Peigen Xie, Tao Song, Jian Chen, Heng Zhao, Zhengshan Liu, Xi Chen, Jianing Ding, Xintian Ding, Ao Shao, Miaomiao Wu, Fengdong Zhao, Siyue Tao, Tao You   +14 more
wiley   +1 more source

Electroacupuncture Upregulated Ghrelin in Rats with Functional Dyspepsia via AMPK/TSC2/Rheb-Mediated mTOR Inhibition [PDF]

, 2019
Lei Tang, Yi Zeng, Lei Li, Jingjing Wang, Duo Peng, Ting Zhang, Hongxing Zhang, Xue An   +7 more
openalex   +1 more source