Results 1 to 10 of about 117,564 (119)
The neuroprotective effect of Rho-kinase Inhibition in 1-methyl-4-phenylpyridinium (MPP+)-induced cellular model of neurodegeneration [PDF]
Medicinski Podmladak, 2021 Introduction: The 1-methyl 4-phenyl 1,2,3,6-tetrahydropiridium (MPTP) induced model of neurodegeneration in Parkinson's disease (PD) is one of the most commonly used experimental models.
Blagojević Sanja +2 more
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Melatonin postconditioning combined with sitagliptin exerts full cardioprotection in diabetic hearts of aged rats through an AMPK-dependent mechanism [PDF]
Archives of Biological Sciences, 2021 The presence of multiple comorbidities in patients facing myocardial ischemia-reperfusion (IR) injury is the main obstacle for cardioprotection. This study investigated the effect of melatonin postconditioning combined with sitagliptin pretreatment on ...
Song Ronggang +3 more
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Quarter-Century Explorations of Bioactive Polyphenols: Diverse Health Benefits
Frontiers in Bioscience-Landmark, 2022 Polyphenols, members of phytochemical superfamily rich in vegetables and fruits, include flavonoids, non-flavonoids, and phenolic acids. Their biological effects includes classical antioxidation (e.g., radical-scavenging, metal chelating, NOX inhibition,
Arthur J. Chu
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Environmental Health and Preventive Medicine, 2023 Background: In this study, we aimed to investigate the effects of acute and chronic resistance training of varying intensities on molecular responses and their association with muscular fitness in a cohort of young males who participated in this ...
Chongwen Zuo +4 more
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What’s new in chronic pain pathophysiology
Canadian Journal of Pain, 2020 The understanding of pain pathophysiology is continuously evolving. Identifying underlying cellular and subcellular pathways helps create opportunities for targeted therapies that may prove to be effective interventions. This article is an update on four
Ivan Cohen, Mark J. Lema
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Available CALM (calmodulin) and autophagy: pas de deux at rest
Autophagy Reports, 2022 Macroautophagy/autophagy is a process that degrades unnecessary cellular components to maintain homeostasis. The Ca2+-sensing protein CALM (calmodulin) is needed for many cell functions yet is a limiting factor because of its insufficient availability ...
Elizabeth McConnaha +3 more
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Autophagy Function and Regulation in Kidney Disease
Biomolecules, 2020 Autophagy is a dynamic process by which intracellular damaged macromolecules and organelles are degraded and recycled for the synthesis of new cellular components.
Gur P. Kaushal +3 more
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Atg8ylation as a general membrane stress and remodeling response
Cell Stress, 2021 The yeast Atg8 protein and its paralogs in mammals, mammalian Atg8s (mAtg8s), have been primarily appreciated for their participation in autophagy. However, lipidated mAtg8s, including the most frequently used autophagosomal membrane marker LC3B, are ...
Suresh Kumar, Jingyue Jia1, Vojo Deretic
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Neuropsychiatric Disease and Treatment, 2023 Zhimin Ding,1,* Jing Gao,2,* Yixuan Feng,1,* Mengyu Wang,1 Huandong Zhao,1 Ruonan Wu,1 Xinyue Zheng,1 Xiaodong Feng,1,2 Mingyin Lai3 1School of Rehabilitation Medicine, Henan University of Chinese Medicine, Zhengzhou, People’s Republic of ...
Ding Z +8 more
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Journal of Inflammation Research, 2022 Ji Zhu,1,* Hang Chen,2,* Jianan Guo,2 Chen Zha,1 Dezhao Lu2 1The Third Affiliated Hospital of Zhejiang Chinese Medical University (Zhongshan Hospital of Zhejiang Province), Hangzhou, People’s Republic of China; 2School of Life Sciences, Zhejiang ...
Zhu J, Chen H, Guo J, Zha C, Lu D
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