Results 311 to 320 of about 427,120 (360)

Menin-driven mTOR signaling sustains taxane resistance in CRPC and reveals a targetable vulnerability for combination therapy. [PDF]

Cell Commun Signal
Bulut I, Cevatemre B, Yuksel-Catal N, Syed H, Onder T, Acilan C.   +5 more
europepmc   +1 more source

Bufalin: a potential drug for regulating EGFR-TKIs resistance in lung cancer via the EGFR-PI3K/Akt-mTOR signaling

Yueqin Bai, Yabin Gong, Ruifang Cui, Qingpeng Deng, Xiaozhen ZHAO, Chang Liu, Longke Dong   +6 more
openalex   +1 more source

Quercetin Regulates Autophagy to Inhibit PRRSV Replication Through the PI3K/Akt/mTOR Signaling Pathway. [PDF]

Viruses
Yang Y, Li X, Shi H, Yu J, Gao C, Liu Y, Feng W, Peng L, Fu B, Yi P.   +9 more
europepmc   +1 more source

Correction to "Discussion on the Mechanism of Gandoufumu Decoction Attenuates Liver Damage of Wilson's Disease by Inhibiting Autophagy through the PI3K/Akt/mTOR Pathway Based on Network Pharmacology and Experimental Verification". [PDF]

Mediators Inflamm
europepmc   +1 more source

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mTOR — beyond transplantation

Current Opinion in Pharmacology, 2005
mTOR kinase plays a central role in the activation of many cell types, and blocking mTOR function with rapamycin results in arrest of the cell cycle at the G1 phase. Recently, several additional molecules have been identified in the mTOR pathway, providing further opportunities to interfere with cell activation and develop novel therapeutic agents ...
Deborah A, Young, Cheryl L, Nickerson-Nutter   +1 more
openaire   +2 more sources