Mettl8 Regulates Hippocampal Neural Stem Cell Proliferation and Neurogenesis via mTOR/4E-BP1 Signaling. [PDF]
CNS Neurosci TherXu J +7 more
europepmc +1 more source
RETRACTION: Thyroxine Alleviates Energy Failure, Prevents Myocardial Cell Apoptosis, and Protects against Doxorubicin-Induced Cardiac Injury and Cardiac Dysfunction via the LKB1/AMPK/mTOR Axis in Mice. [PDF]
Dis MarkersMarkers D.
europepmc +1 more source
Cross-Disorder Pruning-Plasticity-Aging Architecture in Substance Use Disorders and Anxiety: Transcriptome-Wide Association Insights and Mechanistic Synthesis. [PDF]
CureusCheung N.
europepmc +1 more source
Inhibition of FKBP51 alleviates depressive-like behaviors via AKT/mTOR-dependent autophagy and synaptic plasticity. [PDF]
Int J NeuropsychopharmacolLi C +7 more
europepmc +1 more source
Therapeutic potential of asparagus polysaccharide in bladder cancer treatment via modulation of PI3K/AKT/mTOR signaling. [PDF]
Sci RepWang J, Liu H, Li K, Xie Z.
europepmc +1 more source
Plumbagin Induces Cell Cycle Arrest and Autophagy and Suppresses Epithelial to Mesenchymal Transition Involving PI3K/Akt/mTOR-Mediated Pathway in Human Pancreatic Cancer Cells [Retraction]. [PDF]
Drug Des Devel Thereuropepmc +1 more source
mTOR Signaling in Growth, Metabolism, and Disease
Cell, 2017 The mechanistic Target of Rapamycin (mTOR) coordinates eukaryotic cell growth and metabolism with environmental inputs including nutrients and growth factors.
Robert A Saxton, David M Sabatini
exaly +3 more sources
mTOR at the nexus of nutrition, growth, ageing and disease
Nature Reviews Molecular Cell Biology, 2020 The mTOR pathway integrates a diverse set of environmental cues, such as growth factor signals and nutritional status, to direct eukaryotic cell growth. Over the past two and a half decades, mapping of the mTOR signalling landscape has revealed that mTOR
Grace Y Liu +2 more
exaly +2 more sources