Results 51 to 60 of about 302,510 (295)

Berberine, a natural plant product, Inhibits Cell Growth in Human Cancer cells compared with healthy cells

Biobacta Journal of Biochemistry and Molecular Biology
Berberine, an isoquinoline derivative alkaloid, has recently been shown to have cytotoxicity and antitumor activity. The present study aimed to investigate the effect of Berberine at different concentrations (400, 200, 100, 50, 25µg/ml) on cell culture ...
Ahmed Alshanon
doaj   +1 more source

Determination of cell survival after irradiation via clonogenic assay versus multiple MTT Assay - A comparative study

Radiation Oncology, 2012
For studying proliferation and determination of survival of cancer cells after irradiation, the multiple MTT assay, based on the reduction of a yellow water soluble tetrazolium salt to a purple water insoluble formazan dye by living cells was modified ...
Buch Karl, Peters Tanja, Nawroth Thomas, Sänger Markus, Schmidberger Heinz, Langguth Peter   +5 more
doaj   +1 more source

Changes in 2-fluoro-2-deoxy-D-glucose incorporation, hexokinase activity and lactate production by breast cancer cells responding to treatment with the anti-HER-2 antibody trastuzumab [PDF]

, 2010
Peer reviewedPublisher ...
Cheyne, Richard, W., McLaughlin, Abbie, Smith, Timothy Andrew Davies, Trembleau, Laurent Alain Claude   +3 more
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Chemical compositions and antifungal activities of Satureja macrosiphon against Candida and Aspergillus species [PDF]

Current Medical Mycology, 2019
Background and Purpose: Despite the various applications of Satureja species, there are limited data in this domain. Regarding this, the present study was conducted to investigate the essential oil (EO) biological activity of S.
Marjan Motamedi Motamedi, Mohammad Jamal Saharkhiz, Keyvan Pakshir, Sara Amini Akbarabadi, Marzieh Alikhani Khordshami, Fatemeh Asadian, Zahra Zareshahrabadi, Kamiar Zomorodian   +7 more
doaj   +1 more source

Combinations of isoform-targeted histone deacetylase inhibitors and bryostatin analogues display remarkable potency to activate latent HIV without global T-cell activation [PDF]

, 2017
Current antiretroviral therapy (ART) for HIV/AIDS slows disease progression by reducing viral loads and increasing CD4 counts. Yet ART is not curative due to the persistence of CD4+ T-cell proviral reservoirs that chronically resupply active virus ...
Albert, Brice J, Barnes, Alexander B, Kyei, George B, Marshall, Garland R, Niu, Austin, Ramani, Rashmi, Ratner, Lee, Wender, Paul A, Williams, Robert M   +8 more
core   +2 more sources

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Synthesizing efficacious genistein in conjugation with superparamagnetic Fe₃O₄ decorated with bio-compatible carboxymethylated chitosan against acute leukemia lymphoma [PDF]

, 2014
Background Genistein (C15H10O5) is a soy isoflavone with anti-cancer properties such as inhibition of cell growth, proliferation and tumor invasion, but effective dosage against hematopoietic malignant cells was not in non-toxic range.
A Kraay, A Mccloskey, A R Hall, A R Hall, B E Hansen, B E Hansen, C Audet, C Sanderson, C Sharpsteen, D Acemoglu, D Berkowitz, D Eddelbuettel, D Eddelbuettel, D Eddelbuettel, D Rodrik, D W K Andrews, D W K Andrews, D W K Andrews, D W K Andrews, F Schorfheide, Francis DiTraglia, G Claeskens, G Claeskens, G Claeskens, G Claeskens, G G Judge, G Kuersteiner, H Hong, H Leeb, H Leeb, H Leeb, H Leeb, J D Sachs, J Fox, J S Racine, K Carstensen, K Jana, Le Digabel, M Abramson, M Demetrescu, M J Silvapulle, N L Hjort, P C B Phillips, P Guggenberger, P Guggenberger, P Guggenberger, P Kabaila, P Kabaila, R Core Team, R L Berger, S G Donald, S G Donald, S T Buckland, T G Conley, W Easterly, W K Newey, W K Newey, W.-Y Loh, X Chen, X Cheng, X Cheng, Y Yang, Z Liao, Z Xiao   +63 more
core   +3 more sources

CYTOTOXIC ACTIVITY OF BASIL SEEDS( Ocimum baslicum L) EXTRACTS ON SOME BREAST CANCER CELL LINES ( IN VITRO)

The Iraqi Journal of Agricultural science, 2023
In this study, four types of basil seed extracts were used, being cold aqueous extract, hot aqueous extract, petroleum ether extract, and methanolic extract.Nine concentrations (10000, 5000, 2500, 1250, 625, 312.56, 156.25, 78.125, 39.0, 0.0) µg/ml were
Ayeda M.M, J. M. Awda
doaj   +1 more source

MTT assay v1

, 2023
Protocol for MTT cytotoxicity assay on SH-SY5Y cells.
openaire   +1 more source