Results 181 to 190 of about 28,581 (233)
Some of the next articles are maybe not open access.
Cancer Immunology, Immunotherapy, 2000
Analyses of MUC1-specific cytotoxic T cell precursor (CTLp) frequencies were performed in mice immunized with three different MUC1 vaccine immunotherapeutic agents. Mice were immunized with either a fusion protein comprising MUC1 and glutathione S-transferase (MUC1-GST), MUC1-GST fusion protein coupled to mannan (MFP) or with a recombinant vaccinia ...
Vasso Apostolopoulos +2 more
exaly +3 more sources
Analyses of MUC1-specific cytotoxic T cell precursor (CTLp) frequencies were performed in mice immunized with three different MUC1 vaccine immunotherapeutic agents. Mice were immunized with either a fusion protein comprising MUC1 and glutathione S-transferase (MUC1-GST), MUC1-GST fusion protein coupled to mannan (MFP) or with a recombinant vaccinia ...
Vasso Apostolopoulos +2 more
exaly +3 more sources
MUC1 expression in plasmacytoma
Leukemia Research, 2001Plasmacytoma (Pm) is a plasma cell (PC) neoplasia consisting of PCs and some of them show progression to multiple myeloma. But there is no clear indicators predicting this progression. In this study, MUC1 expression was evaluated in Pm cases to determine the predictive value and was compared with histopathologic grade which is known to be a prognostic ...
Paydaş S. +4 more
openaire +3 more sources
MUC1 and the Immunobiology of Cancer
Journal of Mammary Gland Biology and Neoplasia, 2002The membrane epithelial mucin MUC1 is expressed at the luminal surface of most simple epithelial cells, but expression is greatly increased at lactation and in most breast carcinomas. The increase in level of expression of MUC1 in breast cancer is accompanied by changes in the profile of glycosyl transferases involved in the synthesis of the O-glycans ...
Taylor-Papadimitriou, J +6 more
openaire +3 more sources
MUC1, The Renaissance Molecule
Journal of Mammary Gland Biology and Neoplasia, 2001MUC1 is a large, heavily glycosylated mucin expressed on the apical surfaces of most simple, secretory epithelia including the mammary gland, gastrointestinal, respiratory, urinary and reproductive tracts. Although MUC1 was thought to be an epithelial-specific protein, it is now known to be expressed on a variety of hematopoietic cells as well.
openaire +2 more sources
Nature Reviews Cancer, 2012
The UK press got carried away with a cancer story this week. It seems that a universal cancer vaccine is on its way, despite the fact that it has only been trialled in ten patients (with five more still to be recruited).
openaire +1 more source
The UK press got carried away with a cancer story this week. It seems that a universal cancer vaccine is on its way, despite the fact that it has only been trialled in ten patients (with five more still to be recruited).
openaire +1 more source
MUC1 in Endometriosis and Ovarian Cancer
Immunologic Research, 2006Endometriosis is a chronic, debilitating disease, associated with pelvic pain and infertility. Recent epidemiological studies suggest that women with endometriosis are at increased risk for ovarian cancer. Although the causative factors for both endometriosis and ovarian cancer remain largely unknown, several similarities between the proposed etiology ...
Anda M, Vlad +2 more
openaire +2 more sources
BJU International, 2003
OBJECTIVE To detect the expression and transcription pattern of MUC1 in benign and malignant disease, and in two widely studied cell lines, and to investigate the glycosylation of MUC‐1 in bone metastasis of prostate cancer, as mucins have been implicated in the progression and behaviour of several cancers.
I C, Schut +6 more
openaire +2 more sources
OBJECTIVE To detect the expression and transcription pattern of MUC1 in benign and malignant disease, and in two widely studied cell lines, and to investigate the glycosylation of MUC‐1 in bone metastasis of prostate cancer, as mucins have been implicated in the progression and behaviour of several cancers.
I C, Schut +6 more
openaire +2 more sources
Tolerance and immunity to MUC1 in a human MUC1 transgenic murine model.
Cancer research, 1998The human epithelial mucin, MUC1, is a large transmembrane glycoprotein that is expressed on most simple epithelia. It is overexpressed and aberrantly glycosylated on many human epithelial tumors, including more than 90% of human breast cancers. MUC1 is of interest as an immunotherapy target because patients with breast, ovarian, and pancreatic cancers
G J, Rowse +4 more
openaire +1 more source
MUC1: Structure, Function, and Clinic Application in Epithelial Cancers
International Journal of Molecular Sciences, 2021Shiqing Zhang, Joshua Ko, Zhu Zhang
exaly