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Mucin Level as a Potential Biomarker for Breast Cancer Diagnosis
MCBS (Molecular and Cellular Biomedical Sciences), 2022 Background: Breast cancer is the second leading cause of cancer death and a health problem worldwide. Secreted mucins are upregulated in ductal adenocarcinoma of the breast, however, the use of mucin as breast cancer biomarker has not been established ...
Tagwa Sayed Abdihalim +1 more
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Scientific Reports, 2023 To close the gap between ultra-hygienic research mouse models and the much more environmentally exposed conditions of humans, we have established a system where laboratory mice are raised under a full set of environmental factors present in a ...
Henriette Arnesen +7 more
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Annals of Dermatology, 2018 Mucinous nevus is an uncommon entity classified as either a cutaneous mucinosis or a connective tissue nevus. The condition presents as grouped papules and coalescent plaques growing in a unilateral or zosteriform manner. The key histopathological feature is a band-like deposition of mucin in the superficial dermis.
Min Young Lee +3 more
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A Preliminary Study Examining the Binding Capacity of Akkermansia muciniphila and Desulfovibrio spp., to Colonic Mucin in Health and Ulcerative Colitis. [PDF]
PLoS ONE, 2015 Akkermansia muciniphila and Desulfovibrio spp. are commensal microbes colonising the mucus gel layer of the colon. Both species have the capacity to utilise colonic mucin as a substrate. A.
Helen Earley +10 more
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Frontiers in Allergy, 2023 IntroductionEosinophilic Esophagitis (EoE) is a chronic allergic disease characterized by progressive inflammation of the esophageal mucosa. This chronic inflammatory disorder affects up to 50 per 100,000 individuals in the United States and Europe yet ...
Holly A. Morrison +10 more
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Up-regulation of MUC2 and IL-1β expression in human colonic epithelial cells by Shigella and its interaction with mucins. [PDF]
PLoS ONE, 2011 BackgroundThe entire gastrointestinal tract is protected by a mucous layer, which contains complex glycoproteins called mucins. MUC2 is one such mucin that protects the colonic mucosa from invading microbes.
Radhakrishnan Prakash +3 more
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Breakdown of mucin as barrier to digestive enzymes in the ischemic rat small intestine. [PDF]
PLoS ONE, 2012 Loss of integrity of the epithelial/mucosal barrier in the small intestine has been associated with different pathologies that originate and/or develop in the gastrointestinal tract.
Marisol Chang +3 more
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Frontiers in Microbiology, 2023 Mucins are important glycoproteins that form a protective layer throughout the gastrointestinal and respiratory tracts. There is scientific evidence of increase in phage-resistance in the presence of mucin for some bacterial pathogens.
Olga Pacios +26 more
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Mucin1 and Mucin16: Therapeutic Targets for Cancer Therapy
Pharmaceuticals, 2021 The mucin (MUC) family is a group of highly glycosylated macromolecules that are abundantly expressed in mammalian epithelial cells. MUC proteins contribute to the formation of the mucus barrier and thus have protective functions against infection ...
Dong-Hee Lee +3 more
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Stimulation of neutrophil oxidative burst by calcium phosphate particles with adsorbed mucin
Russian Open Medical Journal, 2021 Objective — Mucin can promote formation of gallstones via precipitation with calcium phosphate. The proinflammatory effect of mucin-coated particles is still unclear, and our aim was to study the role of mucin sorption in activation of neutrophil ...
Elena V. Mikhalchik +9 more
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