Results 271 to 280 of about 133,349 (299)
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Molecular beacon-based quantitiation of epithelial tumor marker mucin 1
Bioorganic & Medicinal Chemistry Letters, 2012Mucin 1 (Muc1) is a glycoprotein expressed on most epithelial cell surfaces, which has been confirmed as a useful biomarker for the diagnosis of early cancers. In this study, we demonstrate that a quantum dot (QD)-aptamer beacon acts by folding-induced dissociation of a DNA intercalating dye, BOBO-3, in the presence of the target molecules, Muc1 ...
Seonmi, Shin +4 more
openaire +2 more sources
Synthesis and antibody recognition of mucin 1 (MUC1)-?-conotoxin chimera
Journal of Peptide Science, 2000We synthesized and characterized new chimera peptides by inserting an epitope of the mucin 1 glycoprotein (MUC1) as a 'guest' sequence in the 'host' structure of alpha-conotoxin GI, a 13-residue peptide (ECCNPACGRHYSC) isolated from the venom of Conus geographus.
E, Drakopoulou +5 more
openaire +2 more sources
Update on Mucin-1 immunotherapy in cancer: a clinical perspective
Expert Opinion on Biological Therapy, 2015Mucin 1 (MUC1) is particularly well suited as a cancer immunotherapy target due to the elevated protein expression and aberrant forms associated with malignancy. A variety of therapeutic strategies have been explored, including antibodies intended to induce cancer cell destruction, and vaccinations with peptides, tumor extracts, and gene expression ...
Gareth, Rivalland +2 more
openaire +2 more sources
MicroRNA-199a mediates mucin 1 expression in mouse uterus during implantation
Reproduction, Fertility and Development, 2013Embryo implantation is a complicated process involving interactions between the blastocyst and the luminal epithelium of the receptive uterus. Mucin 1 (MUC1) is an integral membrane glycoprotein expressed apically by secretory epithelial cells and the glandular epithelium in different organs, including the uterus.
Wilasinee, Inyawilert +3 more
openaire +2 more sources
Role of Mucin 1 and Glycodelin A in recurrent implantation failure
Fertility and Sterility, 2015To evaluate and compare the levels of Mucin 1 (MUC-1) and Glycodelin A (GdA) in precisely timed endometrial biopsies and blood samples taken from women with recurrent implantation failure, and women with proven fertility, in a control group.Molecular studies in human blood and tissue.University hospital.Women with recurrent implantation failure and ...
Ercan Bastu +7 more
openaire +2 more sources
Identification of Allobaculum mucolyticum as a novel human intestinal mucin degrader
Gut Microbes, 2021Guus H Van Muijlwijk +2 more
exaly
Assembly Mechanism of Mucin and von Willebrand Factor Polymers
Cell, 2020Gabriel Javitt +2 more
exaly

