Results 271 to 280 of about 133,349 (299)
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Molecular beacon-based quantitiation of epithelial tumor marker mucin 1

Bioorganic & Medicinal Chemistry Letters, 2012
Mucin 1 (Muc1) is a glycoprotein expressed on most epithelial cell surfaces, which has been confirmed as a useful biomarker for the diagnosis of early cancers. In this study, we demonstrate that a quantum dot (QD)-aptamer beacon acts by folding-induced dissociation of a DNA intercalating dye, BOBO-3, in the presence of the target molecules, Muc1 ...
Seonmi, Shin   +4 more
openaire   +2 more sources

Synthesis and antibody recognition of mucin 1 (MUC1)-?-conotoxin chimera

Journal of Peptide Science, 2000
We synthesized and characterized new chimera peptides by inserting an epitope of the mucin 1 glycoprotein (MUC1) as a 'guest' sequence in the 'host' structure of alpha-conotoxin GI, a 13-residue peptide (ECCNPACGRHYSC) isolated from the venom of Conus geographus.
E, Drakopoulou   +5 more
openaire   +2 more sources

Update on Mucin-1 immunotherapy in cancer: a clinical perspective

Expert Opinion on Biological Therapy, 2015
Mucin 1 (MUC1) is particularly well suited as a cancer immunotherapy target due to the elevated protein expression and aberrant forms associated with malignancy. A variety of therapeutic strategies have been explored, including antibodies intended to induce cancer cell destruction, and vaccinations with peptides, tumor extracts, and gene expression ...
Gareth, Rivalland   +2 more
openaire   +2 more sources

MicroRNA-199a mediates mucin 1 expression in mouse uterus during implantation

Reproduction, Fertility and Development, 2013
Embryo implantation is a complicated process involving interactions between the blastocyst and the luminal epithelium of the receptive uterus. Mucin 1 (MUC1) is an integral membrane glycoprotein expressed apically by secretory epithelial cells and the glandular epithelium in different organs, including the uterus.
Wilasinee, Inyawilert   +3 more
openaire   +2 more sources

Role of Mucin 1 and Glycodelin A in recurrent implantation failure

Fertility and Sterility, 2015
To evaluate and compare the levels of Mucin 1 (MUC-1) and Glycodelin A (GdA) in precisely timed endometrial biopsies and blood samples taken from women with recurrent implantation failure, and women with proven fertility, in a control group.Molecular studies in human blood and tissue.University hospital.Women with recurrent implantation failure and ...
Ercan Bastu   +7 more
openaire   +2 more sources

Identification of Allobaculum mucolyticum as a novel human intestinal mucin degrader

Gut Microbes, 2021
Guus H Van Muijlwijk   +2 more
exaly  

The role of MUC2 mucin in intestinal homeostasis and the impact of dietary components on MUC2 expression

International Journal of Biological Macromolecules, 2020
Jianxin Zhao, Qixiao Zhai
exaly  

Assembly Mechanism of Mucin and von Willebrand Factor Polymers

Cell, 2020
Gabriel Javitt   +2 more
exaly  

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