Results 41 to 50 of about 21,378,583 (297)

Heterogeneity and persistence length in human ocular mucins [PDF]

, 2002
Atomic force microscopy (AFM) has been used to investigate the heterogeneity and flexibility of human ocular mucins and their subunits. We have paid particular attention, in terms of theory and experiment, to the problem of inducing the polymers to ...
Stoll, S., Corfield, A. P., Round, A. N., Corfield, AP, Corfield, A., Miles, M., Gowers, D., Round, A.N., Corfield, A.P., Gowers, DM, Berry, M., Miles, M. J., Miles, M.J., Stoll, S, McMaster, TJ, McMaster, T., Gowers, Darren, McMaster, T. J., Berry, Monica, Berry, MS, McMaster, T.J., Miles, MJ, Round, A., Round, AN   +23 more
core   +1 more source

Mucin-degrading gut commensals isolated from healthy faecal donor suppress intestinal epithelial inflammation and regulate tight junction barrier function

Frontiers in Immunology, 2022
The intestinal epithelium surface is covered by a layer of mucus that harbors a complex and dynamic population of bacteria termed gut microbiota. In particular, some gut bacteria have the ability to degrade the mucin glycan for nutritional sources ...
Mingfang Pan, Nilakshi Barua, Margaret Ip, Margaret Ip   +3 more
doaj   +1 more source

Mucin-1-Antibody-Conjugated Mesoporous Silica Nanoparticles for Selective Breast Cancer Detection in a Mucin-1 Transgenic Murine Mouse Model [PDF]

Journal of Biomedical Nanotechnology, 2016
Mucin-1 (MUC1), a transmembrane glycoprotein is aberrantly expressed on ~90% of breast cancer and is an excellent target for nanoparticulate targeted imaging. In this study, the development of a dye-doped NIR emitting mesoporous silica nanoparticles platform conjugated to tumor-specific MUC1 antibody (ab-tMUC1-NIR-MSN) for in vivo optical detection of ...
Didier, Dréau, Laura Jeffords, Moore, Merlis P, Alvarez-Berrios, Mubin, Tarannum, Pinku, Mukherjee, Juan L, Vivero-Escoto   +5 more
openaire   +2 more sources

Mucin 1 expression correlation with lymph node metastasis and micrometastasis and poor prognosis in patients with esophageal squamous cell carcinomas

Archives of Medical Science, 2019
Introduction Lymph node metastasis (LNM) and lymph node micrometastasis (LNMM) are prognostic factors in esophageal squamous cell carcinoma (ESCC) patients.
Fei Yang, Zhe Li, Jing-Bo Shao, Wei Gao, Zhi-Gang Sun   +4 more
doaj   +1 more source

A Monoclonal Antibody Against the Oncogenic Mucin 1 Cytoplasmic Domain [PDF]

Hybridoma, 2011
Mucin 1 (MUC1) is a heterodimeric protein that is aberrantly overexpressed in diverse human carcinomas and certain hematologic malignancies. The transmembrane MUC1-C subunit confers tumorigenicity and is a target for anti-cancer drug development. In this regard, the MUC1-C cytoplasmic domain interacts with multiple effectors that have been linked to ...
Govind, Panchamoorthy, Hala, Rehan, Akriti, Kharbanda, Rehan, Ahmad, Donald, Kufe   +4 more
openaire   +2 more sources

Microstructural study of mucin: influence of pH, temperature, concentration and nanoparticles [PDF]

, 2020
The aim of this research is to examine the nano- and micro-structure of mucin in response to chemicophysical changes within the aqueous solution. By characterizing the mucin structure across a range of length scales relationships can be developed and ...
Igwe, Onyinyechi
core  

In Vitro Modelling of Barrier Impairment Associated with Gastro-Oesophageal Reflux Disease (GERD)

Clinical and Experimental Gastroenterology, 2021
Marisa Meloni, Paolo Buratti, Francesco Carriero, Laura Ceriotti VitroScreen, In Vitro Innovation Center, Milan, 20149, ItalyCorrespondence: Laura Ceriotti Via Mosè Bianchi, 103, Milan, 20149, ItalyTel +39 02 89077608Email laura.ceriotti@vitroscreen ...
Meloni M, Buratti P, Carriero F, Ceriotti L   +3 more
doaj  

Relation of Gallbladder Motility to Viscosity and Composition of Gallbladder Bile in Patients with Cholesterol Gallstones [PDF]

, 2009
Background/Aims: Increased viscosity and supersaturation of cholesterol in gallbladder bile, as well as an impaired motility of the gallbladder, are considered to be important factors in the pathogenesis of cholesterol gallstones.
Straub, Gundula, Juengst, Christoph, Schneider, Berthold, del Pozo, Reginald, Juengst, Dieter, Neubrand, Michael, Spelsberg, Fritz W., Althaus, Rupert, Gruendel, Denis, Huettl, Thomas P.   +9 more
core   +1 more source

Cornu aspersum mucin attenuates indomethacins-induced gastric ulcers in mice via alleviating oxidative stress and inflammation

Heliyon, 2023
In the past three decades, a significant progress has been made in the prevention and treatment of gastric ulcers. The incidence of the disease has decreased, but gastric ulcer is still a medical problem.
Maha B. Salem, Mohamed Elzallat, Dina Mostafa Mohammed, Safia Samir, Olfat A. Hammam, Marwa Tamim A. Abdel-Wareth   +5 more
doaj   +1 more source

Pro-Resolving Mediator Annexin A1 Regulates Intracellular Ca2+ and Mucin Secretion in Cultured Goblet Cells Suggesting a New Use in Inflammatory Conjunctival Diseases

Frontiers in Immunology, 2021
The amount of mucin secreted by conjunctival goblet cells is regulated to ensure the optimal level for protection of the ocular surface. Under physiological conditions lipid specialized pro-resolving mediators (SPM) are essential for maintaining tissue ...
Anne V. Lyngstadaas, Anne V. Lyngstadaas, Anne V. Lyngstadaas, Markus V. Olsen, Markus V. Olsen, Markus V. Olsen, Jeffrey A. Bair, Robin R. Hodges, Tor P. Utheim, Tor P. Utheim, Tor P. Utheim, Charles N. Serhan, Darlene A. Dartt   +12 more
doaj   +1 more source