Results 21 to 30 of about 21,378,583 (297)

Mucin-1 and its relation to grade, stage and survival in ovarian carcinoma patients [PDF]

BMC Cancer, 2012
Background Mucin-1 is known to be over-expressed by various human carcinomas and is shed into the circulation where it can be detected in patient’s serum by specific anti-Mucin-1 antibodies, such as the tumour marker assays CA 15–3 and CA 27.29.
Engelstaedter Verena, Heublein Sabine, Schumacher Anamur Lan, Lenhard Miriam, Engelstaedter Helen, Andergassen Ulrich, Guenthner-Biller Margit, Kuhn Christina, Rack Brigitte, Kupka Markus, Mayr Doris, Jeschke Udo   +11 more
doaj   +3 more sources

MUCIN 1 in Prostate Cancer

, 2021
ABSTRACT Despite extensive research efforts in prostate cancer for the last several decades, the disease remains a leading cause of cancer death in men in the developed world. A typical feature of prostate cancer initiation and progression is the landscape of genetic alterations, which changes the expression patterns of numerous molecules in prostate ...
Kapoor A, Gu Y, Lin X, Peng J, Major P, Tang D.   +5 more
europepmc   +3 more sources

Mucin 1 deficiency mediates corticosteroid insensitivity in asthma

Allergy, 2018
AbstractBackgroundThe loss of corticosteroid efficacy is an important issue in severe asthma management and may lead to poor asthma control and deterioration of airflow. Recent data indicate that Mucin 1 (MUC1) membrane mucin can mediate corticosteroid efficacy in chronic rhinosinusitis, but the role of MUC1 in uncontrolled severe asthma is unknown ...
Javier Milara, Anselm Morell, Alfredo de Diego, Enrique Artigues, Esteban Morcillo, Julio Cortijo   +5 more
openaire   +8 more sources

PB2485: INVESTIGATING THE EXPRESSION OF MUCIN-1 (MUC-1) DURING ERYTHROID DIFFERENTIATION [PDF]

HemaSphere, 2023
Hammad Hassan, Sarah Yousuf, Areeb Ahmed, Afsar Mian, Sheerien Rajput   +4 more
doaj   +2 more sources

IL-22 regulates endometrial regeneration by enhancing tight junctions and orchestrating extracellular matrix

Frontiers in Immunology, 2022
The uterine endometrium uniquely regenerates after menses, postpartum, or after breaks in the uterine layer integrity throughout women’s lives. Direct cell–cell contacts ensured by tight and adherens junctions play an important role in endometrial ...
Umida Ganieva, Sylvia Schneiderman, Pengli Bu, Kenneth Beaman, Kenneth Beaman, Svetlana Dambaeva, Svetlana Dambaeva   +6 more
doaj   +1 more source

Nuclear epidermal growth factor receptor as a therapeutic target

Exploration of Targeted Anti-tumor Therapy, 2023
Epidermal growth factor receptor (EGFR) is one of the most well-studied oncogenes with roles in proliferation, growth, metastasis, and therapeutic resistance.
Benjamin Atwell, Pavani Chalasani, Joyce Schroeder   +2 more
doaj   +1 more source

Adeno-associated virus-based caveolin-1 delivery via different routes for the prevention of cholesterol gallstone formation

Lipids in Health and Disease, 2022
Background Hepatic caveolin-1 (CAV1) is reduced in cholesterol gallstone disease (CGD). Mice with CAV1 deficiency were prone to develop CGD. However, it remains unknown whether restored hepatic CAV1 expression prevents the development of CGD.
Sha Li, Hongtan Chen, Xin Jiang, Fengling Hu, Yiqiao Li, Guoqiang Xu   +5 more
doaj   +1 more source

Theragnostic perspectives of Mucin 1 for oral cancer

Oral Oncology Reports
Dharmaraj Senthilkumar, Baskar Venkidasamy   +1 more
doaj   +2 more sources

Expression of aberrantly glycosylated Mucin‐1 in ovarian cancer [PDF]

Histopathology, 2010
Van Elssen C H M J, Frings P W H, Bot F J, Van de Vijver K K, Huls M B, Meek B, Hupperets P, Germeraad W T V & Bos G M J
(2010) Histopathology57, 597–606
Expression of aberrantly glycosylated Mucin‐1 in ovarian cancerAims:  Mucin 1 (MUC1) is an important tumour‐associated antigen (TAA), both overexpressed and aberrantly glycosylated in ...
Van Elssen, Catharina H. M. J., Frings, Peter W. H., Bot, Freek J., Van de Vijver, Koen K., Huls, Mariska B., Meek, Bob, Hupperets, Pierre, Germeraad, Wilfred T. V., Bos, Gerard M. J.   +8 more
openaire   +3 more sources

Mucin Level as a Potential Biomarker for Breast Cancer Diagnosis

MCBS (Molecular and Cellular Biomedical Sciences), 2022
Background: Breast cancer is the second leading cause of cancer death and a health problem worldwide. Secreted mucins are upregulated in ductal adenocarcinoma of the breast, however, the use of mucin as breast cancer biomarker has not been established ...
Tagwa Sayed Abdihalim, Alkhair Abd Almahmoud Idris   +1 more
doaj   +1 more source