Results 11 to 20 of about 116,093,450 (283)
Bmi-1 regulates mucin levels and mucin O-glycosylation in the submandibular gland of mice.
PLoS ONE, 2021 Mucins, the major components of salivary mucus, are large glycoproteins abundantly modified with O-glycans. Mucins present on the surface of oral tissues contribute greatly to the maintenance of oral hygiene by selectively adhering to the surfaces of ...
Akihiko Kameyama +2 more
doaj +2 more sources
Mucin-1 and its relation to grade, stage and survival in ovarian carcinoma patients
BMC Cancer, 2012 Background Mucin-1 is known to be over-expressed by various human carcinomas and is shed into the circulation where it can be detected in patient’s serum by specific anti-Mucin-1 antibodies, such as the tumour marker assays CA 15–3 and CA 27.29.
Engelstaedter Verena +11 more
doaj +2 more sources
Transmembrane Mucin-1 Facilitates Oral Microbial Colonization in Oral Cancer
OralMucins are a family of heavily glycosylated proteins that form the main organic component of the oral mucosal barrier complex. Transmembrane mucin 1 (tMUC1) is anchored at the superficial epithelial surface to provide a protective function.
Bina Kashyap, Arja M. Kullaa
doaj +2 more sources
PB2485: INVESTIGATING THE EXPRESSION OF MUCIN-1 (MUC-1) DURING ERYTHROID DIFFERENTIATION [PDF]
HemaSphere, 2023 Hammad Hassan +4 more
doaj +2 more sources
Identification and characterisation of mucin abnormalities in the ganglionic bowel in Hirschsprung's disease [PDF]
, 2010 MDHirschsprung’s disease (HD) is a congenital abnormality of unknown origin, characterised by a lack of ganglion cells in the distal colon which results in functional colonic obstruction.
Speare, Ruth Marian
core +4 more sources
Frontiers in Immunology, 2022 The uterine endometrium uniquely regenerates after menses, postpartum, or after breaks in the uterine layer integrity throughout women’s lives. Direct cell–cell contacts ensured by tight and adherens junctions play an important role in endometrial ...
Umida Ganieva +6 more
doaj +1 more source
Molecular Therapy: Oncolytics, 2021 Vaccinia virus (VV) is a powerful tool for cancer treatment with the potential for tumor tropism, efficient cell-to-cell spread, rapid replication in cancer cells, and stimulation of anti-tumor immunity.
Claudia Hill +9 more
doaj +1 more source
Nuclear epidermal growth factor receptor as a therapeutic target
Exploration of Targeted Anti-tumor Therapy, 2023 Epidermal growth factor receptor (EGFR) is one of the most well-studied oncogenes with roles in proliferation, growth, metastasis, and therapeutic resistance.
Benjamin Atwell +2 more
doaj +1 more source
Lipids in Health and Disease, 2022 Background Hepatic caveolin-1 (CAV1) is reduced in cholesterol gallstone disease (CGD). Mice with CAV1 deficiency were prone to develop CGD. However, it remains unknown whether restored hepatic CAV1 expression prevents the development of CGD.
Sha Li +5 more
doaj +1 more source
Steroidal but not embryonic regulation of mucin 1 expression in bovine endometrium. [PDF]
J Reprod Dev, 2021 In cow herd management, inadequate embryo implantation leads to pregnancy loss and causes severe economic losses. Thus, it is crucial to understand the molecular mechanisms underlying endometrial receptivity and subsequent embryo implantation. Transmembrane glycocalyx mucin 1 (MUC1) has a large and highly glycosylated extracellular domain known to ...
Kubota K +4 more
europepmc +5 more sources