Results 231 to 240 of about 188,185 (313)

Airway Mucosal Defense: Mucins, Innate Immunity, and Contemporary Mucoactive Strategies. [PDF]

Biomedicines
Akparova A, Kurmanova G, Omarova G, Kurmanova A, Zhunisbek M, Bapaeva M, Zhankina Z, Sadykova S, Abdrakhmanova A, Samadin A.   +9 more
europepmc   +1 more source

GSK3β drives early diabetic tubulopathy via TFEB‐mediated mitochondrial dysfunction

Interdisciplinary Medicine, EarlyView.
Mitochondrial dysfunction, including mitochondrial biogenesis, mitophagy, dynamics and oxidative stress, occurs in the early stages of diabetic tubulopathy, which precede proteinuria and renal histological changes. GSK3β is a potential novel biomarker for the prediction of diabetic tubulopathy.
Lan Yao, Xianhui Liang, Bingyu Li, Bohan Chen, Xiaoyang Wang, Mei Hong, Qi Feng, Yingjin Qiao, Zhangsuo Liu, Kai Wang, Pei Wang   +10 more
wiley   +1 more source

Novel Perspectives on the Relationship Between the Gastrointestinal Mucus Barrier and Soybean Agglutinin. [PDF]

Cells
E T, Xia J, Xu C, Fan X, Zhang B, Bao N, Zhao Y, Qin G, Ji Y, Zhang S, Ahmed S, Elken EM, Eldawy MH, Pan L, Farouk MH, Wu Z.   +15 more
europepmc   +1 more source

Integrated one‐pot CRISPR‐Cas detection: Addressing strategies and future prospects

Interdisciplinary Medicine, EarlyView.
Integrated one‐pot CRISPR‐Cas detection significantly simplifies workflows, reduces cross‐contamination risks, and shortens turnaround times, making it highly suitable for point‐of‐care testing (POCT) and resource‐limited settings. Key challenges include system compatibility issues between Cas proteins and isothermal amplification, limited multiplexing
Jian Zhou, Xuemei Ren, Yingjie Ren, Ruiping Wu, Ruiman Geng, Le Chen, Zhuo Li   +6 more
wiley   +1 more source

Mucinase from <i>Bacteroides</i> <i>thetaiotaomicron</i> as mucolytic for mucinous cancer pseudomyxoma peritonei. [PDF]

Front Microbiol
Liu J, Zhan L, Xu C, Wei R, Bai C, Guan M, Sun Z.   +6 more
europepmc   +1 more source

Colonic Barrier Dysfunction and Inflammation Induced by Nano‐/Micro‐Plastics Fibers in Mice via the FAK/NF‐κB/iNOS and TLR4/NF‐κB/iNOS Pathways

Journal of Applied Toxicology, EarlyView.
ABSTRACT As emerging environmental contaminants, nano‐ and micro‐plastics (NMPs) have drawn increasing research attention due to potential hazards to organisms. Particle shape is a key factor influencing the toxic effects of NMPs, and NMPs of different shapes cause varying degrees of tissue damage. We investigated the specific mechanisms of polystyrene
Yuting Li, Shibo Bao, Puyang Huang, Jiahui Wang, Hongfeng Li, Yahong Liu, Kai Wang, Jianjun Du, Lingjun Yan, Guowei Pan, Wei Sun   +10 more
wiley   +1 more source

Lubricin's Mucin Domain Has Strong Polyproline Type II Helical Character. [PDF]

Comput Struct Biotechnol J
Feng BN, Marks AJ, Kim FS, Naik M, Schmidt TA, Elsaid KA, Jay GD, Rubenstein BM.   +7 more
europepmc   +1 more source

Application of Serum CA125, HE4, ROMA, and CPH‐I in the Preoperative Differentiation of Ovarian Tumors: A Diagnostic Accuracy Study

Journal of Clinical Laboratory Analysis, EarlyView.
This study evaluated the diagnostic performance of CA125, HE4, ROMA, and CPH‐I in 345 patients with histologically confirmed ovarian tumors. CPH‐I showed favorable diagnostic performance overall and was particularly valuable in premenopausal women, whereas ROMA‐based strategies demonstrated optimal performance in postmenopausal women.
Weiming Feng, Chunying Zhang, Lingxin Meng, Yifei Chen, Haiyun Yu, Yanhong Zhai, Zheng Cao   +6 more
wiley   +1 more source

Qualitative beta-2-adrenoceptor signaling in the regulation of human airway epithelia mucin and cytokine production. [PDF]

Respir Res
Graumuller F, Cervantes D, Chan TO, Schaunaman N, Villalba DR, Dickey BF, Walker JKL, Chu HW, Penn RB.   +8 more
europepmc   +1 more source