Results 11 to 20 of about 188,185 (313)

Sialidases and fucosidases of Akkermansia muciniphila are crucial for growth on mucin and nutrient sharing with mucus-associated gut bacteria

open access: yesNature Communications, 2023
This study offers molecular insight into the sialidase and fucosidase decapping apparatus that initiates growth on mucin and promotes nutrient sharing by the dedicated mucolytic symbiont Akkermansia muciniphila with the mucus-associated microbiota.
Bashar Shuoker   +14 more
semanticscholar   +1 more source

Mucinous Nevus [PDF]

open access: yesAnnals of Dermatology, 2018
Mucinous nevus is an uncommon entity classified as either a cutaneous mucinosis or a connective tissue nevus. The condition presents as grouped papules and coalescent plaques growing in a unilateral or zosteriform manner. The key histopathological feature is a band-like deposition of mucin in the superficial dermis.
Min Young Lee   +3 more
openaire   +2 more sources

A genetic system for Akkermansia muciniphila reveals a role for mucin foraging in gut colonization and host sterol biosynthesis gene expression

open access: yesNature Microbiology, 2023
Akkermansia muciniphila, a mucophilic member of the gut microbiota, protects its host against metabolic disorders. Because it is genetically intractable, the mechanisms underlying mucin metabolism, gut colonization and its impact on host physiology are ...
L. Davey   +9 more
semanticscholar   +1 more source

A Preliminary Study Examining the Binding Capacity of Akkermansia muciniphila and Desulfovibrio spp., to Colonic Mucin in Health and Ulcerative Colitis. [PDF]

open access: yesPLoS ONE, 2015
Akkermansia muciniphila and Desulfovibrio spp. are commensal microbes colonising the mucus gel layer of the colon. Both species have the capacity to utilise colonic mucin as a substrate. A.
Helen Earley   +10 more
doaj   +1 more source

Mucin degrader Akkermansia muciniphila accelerates intestinal stem cell-mediated epithelial development

open access: yesGut microbes, 2021
Mucin-degrading bacteria are densely populated in the intestinal epithelium; however, their interaction with intestinal stem cells (ISCs) and their progeny have not been elucidated.
Seungil Kim   +9 more
semanticscholar   +1 more source

Up-regulation of MUC2 and IL-1β expression in human colonic epithelial cells by Shigella and its interaction with mucins. [PDF]

open access: yesPLoS ONE, 2011
BackgroundThe entire gastrointestinal tract is protected by a mucous layer, which contains complex glycoproteins called mucins. MUC2 is one such mucin that protects the colonic mucosa from invading microbes.
Radhakrishnan Prakash   +3 more
doaj   +1 more source

Expression profiling identifies key genes and biological functions associated with eosinophilic esophagitis in human patients

open access: yesFrontiers in Allergy, 2023
IntroductionEosinophilic Esophagitis (EoE) is a chronic allergic disease characterized by progressive inflammation of the esophageal mucosa. This chronic inflammatory disorder affects up to 50 per 100,000 individuals in the United States and Europe yet ...
Holly A. Morrison   +10 more
doaj   +1 more source

Effects induced by polyethylene microplastics oral exposure on colon mucin release, inflammation, gut microflora composition and metabolism in mice.

open access: yesEcotoxicology and Environmental Safety, 2021
Microplastics are plastic fragments widely distributed in the environment and accumulate in the organisms. However, the research on microplastics effects in mammals is limited. Polyethylene is the main kind of microplastics in the environment.
Hanqing Sun   +4 more
semanticscholar   +1 more source

Breakdown of mucin as barrier to digestive enzymes in the ischemic rat small intestine. [PDF]

open access: yesPLoS ONE, 2012
Loss of integrity of the epithelial/mucosal barrier in the small intestine has been associated with different pathologies that originate and/or develop in the gastrointestinal tract.
Marisol Chang   +3 more
doaj   +1 more source

Molecular studies of phages-Klebsiella pneumoniae in mucoid environment: innovative use of mucolytic agents prior to the administration of lytic phages

open access: yesFrontiers in Microbiology, 2023
Mucins are important glycoproteins that form a protective layer throughout the gastrointestinal and respiratory tracts. There is scientific evidence of increase in phage-resistance in the presence of mucin for some bacterial pathogens.
Olga Pacios   +26 more
doaj   +1 more source

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