Results 11 to 20 of about 167,879 (293)
Identification and characterisation of mucin abnormalities in the ganglionic bowel in Hirschsprung's disease [PDF]
, 2010 MDHirschsprung’s disease (HD) is a congenital abnormality of unknown origin, characterised by a lack of ganglion cells in the distal colon which results in functional colonic obstruction.
Speare, Ruth Marian
core +4 more sources
Scientific Reports, 2023 To close the gap between ultra-hygienic research mouse models and the much more environmentally exposed conditions of humans, we have established a system where laboratory mice are raised under a full set of environmental factors present in a ...
Henriette Arnesen +7 more
doaj +1 more source
Determination of Gene-Level Fitness Contributions Across the Mucin-Utilization Network of Bacteroides thetaiotaomicron. [PDF]
Adv Sci (Weinh)Genome‐wide CRISPRi and RNA‐seq resolve how B. thetaiotaomicron converts host mucosal glycans into fitness. The study reveals a layered mucin‐utilization architecture in which capsular polysaccharides constrain surface access, extracellular CAZymes and peptidases show functional redundancy, and intracellular catabolic pathways create discrete metabolic
Kim K +5 more
europepmc +2 more sources
Annals of Dermatology, 2018 Mucinous nevus is an uncommon entity classified as either a cutaneous mucinosis or a connective tissue nevus. The condition presents as grouped papules and coalescent plaques growing in a unilateral or zosteriform manner. The key histopathological feature is a band-like deposition of mucin in the superficial dermis.
Min Young Lee +3 more
openaire +2 more sources
A Preliminary Study Examining the Binding Capacity of Akkermansia muciniphila and Desulfovibrio spp., to Colonic Mucin in Health and Ulcerative Colitis. [PDF]
PLoS ONE, 2015 Akkermansia muciniphila and Desulfovibrio spp. are commensal microbes colonising the mucus gel layer of the colon. Both species have the capacity to utilise colonic mucin as a substrate. A.
Helen Earley +10 more
doaj +1 more source
Up-regulation of MUC2 and IL-1β expression in human colonic epithelial cells by Shigella and its interaction with mucins. [PDF]
PLoS ONE, 2011 BackgroundThe entire gastrointestinal tract is protected by a mucous layer, which contains complex glycoproteins called mucins. MUC2 is one such mucin that protects the colonic mucosa from invading microbes.
Radhakrishnan Prakash +3 more
doaj +1 more source
Frontiers in Allergy, 2023 IntroductionEosinophilic Esophagitis (EoE) is a chronic allergic disease characterized by progressive inflammation of the esophageal mucosa. This chronic inflammatory disorder affects up to 50 per 100,000 individuals in the United States and Europe yet ...
Holly A. Morrison +10 more
doaj +1 more source
Breakdown of mucin as barrier to digestive enzymes in the ischemic rat small intestine. [PDF]
PLoS ONE, 2012 Loss of integrity of the epithelial/mucosal barrier in the small intestine has been associated with different pathologies that originate and/or develop in the gastrointestinal tract.
Marisol Chang +3 more
doaj +1 more source
Frontiers in Microbiology, 2023 Mucins are important glycoproteins that form a protective layer throughout the gastrointestinal and respiratory tracts. There is scientific evidence of increase in phage-resistance in the presence of mucin for some bacterial pathogens.
Olga Pacios +26 more
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Mucin1 and Mucin16: Therapeutic Targets for Cancer Therapy
Pharmaceuticals, 2021 The mucin (MUC) family is a group of highly glycosylated macromolecules that are abundantly expressed in mammalian epithelial cells. MUC proteins contribute to the formation of the mucus barrier and thus have protective functions against infection ...
Dong-Hee Lee +3 more
doaj +1 more source