From fistula to malignancy: rectal mucinous adenocarcinoma arising in a chronic perianal fistula, a rare diagnostic challenge. [PDF]
AlMuhsin AM +5 more
europepmc +1 more source
Patient-Derived iPSC Modeling Reveals Dysregulation of the Mucin-Type O-Glycan Biosynthesis-Related Transcriptional Program in <i>TBX6</i>-Associated Congenital Scoliosis. [PDF]
Hao J +11 more
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Comparative Effectiveness and Safety of Rebamipide Versus Diquafosol in the Treatment of Dry Eye Disease: A Systematic Review and Meta-Analysis. [PDF]
Iqbal M +6 more
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Deciphering the <i>in vitro</i> mucin-driven interaction dynamics of a synthetic gut bacterial community. [PDF]
Yu C +9 more
europepmc +1 more source
Age-related remodeling of the intestinal mucus barrier in pigs: implications for post-weaning diarrhea. [PDF]
Becker CB +8 more
europepmc +1 more source
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Mucins and Mucin Binding Proteins in Colorectal Cancer
Cancer and Metastasis Reviews, 2004Mucins are high-molecular weight epithelial glycoproteins with a high content of clustered oligosaccharides O-glycosidically linked to tandem repeat peptides rich in threonine, serine, and proline. There are two structurally and functionally distinct classes of mucins: secreted gel-forming mucins (MUC2, MUC5AC, MUC5B, and MUC6) and transmembrane mucins
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This is a clinicopathologic study of six patients with mucinous syringometaplasia, which was diagnosed histologically. Biopsies revealed a focal invagination of the epidermis lined by squamous epithelium, with one or several eccrine ducts leading into the vagination. The eccrine duct epithelium contained mucin-laden goblet cells, and there was mucinous
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Mucins represent the main components of gel-like secretions, or mucus, secreted by mucosae or some exocrine glands. These high-molecular-weight glycoproteins are characterized by the large number of carbohydrate chains O-glycosidically linked to the peptide. The determination of mucin molecular weight and conformation has been controversial for several
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Mucin Purification and Printing Natural Mucin Microarrays
2022Mucin glycosylation is the key facilitator of microbial attachment and nutrition and it varies according to biological location, health and disease status, microbiome composition, infection, and multiple other factors. Mucin glycans have also been reported to attenuate pathogen virulence and mediate biofilm dispersal.
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