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The role of MUC2 mucin in intestinal homeostasis and the impact of dietary components on MUC2 expression

International Journal of Biological Macromolecules, 2020
MUC2 mucin is an important secretory protein found in the human gut. Recent studies indicated that MUC2 mucin plays a role in the protection of gut barrier, the regulation of microbiome homeostasis and the prevention of diseases.
Xinjie Yu, Jianxin Zhao, Qixiao Zhai
exaly   +2 more sources

The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2019
Significance Mucin-domain glycoproteins are found in nearly every tissue of the human body, and are important in biological processes ranging from embryogenesis to cancer.
Stacy A Malaker   +2 more
exaly   +2 more sources

Physiologically Inspired Mucin Coated Escherichia coli Nissle 1917 Enhances Biotherapy by Regulating the Pathological Microenvironment to Improve Intestinal Colonization.

ACS Nano, 2022
The delivery of probiotics to the microbiota is a promising method to prevent and treat diseases. However, oral probiotics will suffer from gastrointestinal insults, especially the pathological microenvironment of inflammatory diseases such as reactive ...
Xinyuan Yang   +10 more
semanticscholar   +1 more source

Mucinous syringometaplasia

Journal of the American Academy of Dermatology, 1984
This is a clinicopathologic study of six patients with mucinous syringometaplasia, which was diagnosed histologically. Biopsies revealed a focal invagination of the epidermis lined by squamous epithelium, with one or several eccrine ducts leading into the vagination. The eccrine duct epithelium contained mucin-laden goblet cells, and there was mucinous
K, Scully, D, Assaad
openaire   +2 more sources

The complexity of mucins

Biochimie, 1988
Mucins represent the main components of gel-like secretions, or mucus, secreted by mucosae or some exocrine glands. These high-molecular-weight glycoproteins are characterized by the large number of carbohydrate chains O-glycosidically linked to the peptide. The determination of mucin molecular weight and conformation has been controversial for several
P, Roussel   +7 more
openaire   +2 more sources

Mucin Purification and Printing Natural Mucin Microarrays

2022
Mucin glycosylation is the key facilitator of microbial attachment and nutrition and it varies according to biological location, health and disease status, microbiome composition, infection, and multiple other factors. Mucin glycans have also been reported to attenuate pathogen virulence and mediate biofilm dispersal.
Marie, Le Berre   +5 more
openaire   +2 more sources

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