Results 191 to 200 of about 29,844,027 (286)

The gut microbiome and drug‐resistant epilepsy: Microbiome–antiseizure medication interactions and implications for pharmacoresistance

Epilepsia Open, EarlyView.
Abstract Drug‐resistant epilepsy (DRE) affects approximately one‐third of patients with epilepsy and represents a major unmet clinical need. While traditional hypotheses of pharmacoresistance have focused on alterations in drug targets, efflux transporter overexpression, and intrinsic disease severity, the gut microbiome has recently emerged as a ...
Khaled Zammar, Majd A. AbuAlrob, Musab Ali, Simona Lattanzi, Boulenouar Mesraoua   +4 more
wiley   +1 more source

GMMA decorated with mucin 1 Tn/STn mimetics elicit specific antibodies response and inhibit tumor growth. [PDF]

NPJ Vaccines
Pesce E, Sodini A, Palmieri E, Valensin S, Tinti C, Rossi M, De Rosa A, Fragai M, Papi F, Cordiglieri C, Berti F, Grifantini R, Micoli F, Nativi C.   +13 more
europepmc   +1 more source

Mucin-1 Protein Is a Prognostic Marker for Pancreatic Ductal Adenocarcinoma: Results From the CONKO-001 Study. [PDF]

Front Oncol, 2021
Striefler JK, Riess H, Lohneis P, Bischoff S, Kurreck A, Modest DP, Bahra M, Oettle H, Sinn M, Bläker H, Denkert C, Stintzing S, Sinn BV, Pelzer U.   +13 more
europepmc   +1 more source

Probiotic Spore Inspired Oral Drug Delivery System With Multiple‐Barriers‐Crossing Ability Modulates Gut‐Brain Axis for Parkinson's Disease Therapy

Exploration, EarlyView.
Inspired by the germination of probiotic spores, we utilize the excellent characteristics of spores to break through multiple barriers of oral brain‐targeted delivery. Besides the probiotics mediated gut‐brain communication, the spore coat proteins derived nanosystems with multiple‐barriers‐crossing ability alleviate neurodegeneration.
Qianhua Feng, Yuying Mei, Jia Zhang, Liying Sun, Bingqian Si, Huimin Zhou, Huifang Xiao, Runhan Liu, Jieyun Zhang, Lei Wang   +9 more
wiley   +1 more source

Mucin 1 expression is regulated by hsa_circ_0055054/microRNA‑122‑5p and promotes hepatocellular carcinoma development. [PDF]

Oncol Lett
Hao P, Li Q, Zhao H.
europepmc   +1 more source

Polymer stealthing and mucin-1 retargeting for enhanced pharmacokinetics of an oncolytic vaccinia virus. [PDF]

Mol Ther Oncolytics, 2021
Hill C, Grundy M, Bau L, Wallington S, Balkaran J, Ramos V, Fisher K, Seymour L, Coussios C, Carlisle R.   +9 more
europepmc   +1 more source

Fabrication of a salt‐containing coacervated emulsion: Application in low‐salt mayonnaise with enhanced saltiness perception

Food Biomacromolecules, EarlyView.
Salt‐containing whey protein‐chitosan coacervates enabled stable emulsions with controlled sodium distribution, thereby enhancing perceived saltiness in low‐salt mayonnaise. Improved microstructure, rheology, and stability promoted sodium release during oral processing, offering an effective strategy for sodium reduction without compromising sensory ...
Mingfeng Wu, Xiaoyin Li, Xiaoshan Tang, Yucong Zou, Yang Yuan   +4 more
wiley   +1 more source

Theragnostic perspectives of Mucin 1 for oral cancer

Oral Oncology Reports
Dharmaraj Senthilkumar, Baskar Venkidasamy   +1 more
doaj   +1 more source

Mucin 1 and venous thrombosis in tumor-bearing mice and patients with cancer. [PDF]

Thromb Res
Kawano T, Englisch C, Hisada Y, Paul D, Archibald S, Grover S, Pabinger I, Ay C, Mackman N.   +8 more
europepmc   +1 more source

Mucin 1 Inhibits Ferroptosis and Sensitizes Vitamin E to Alleviate Sepsis-Induced Acute Lung Injury through GSK3β/Keap1-Nrf2-GPX4 Pathway. [PDF]

Oxid Med Cell Longev, 2022
Wang YM, Gong FC, Qi X, Zheng YJ, Zheng XT, Chen Y, Yang ZT, Qing-Ye, Mao EQ, Chen EZ.   +9 more
europepmc   +1 more source