Results 261 to 270 of about 191,997 (296)

Galectin-1 binds mucin in human trophoblast

Histochemistry and Cell Biology, 2014
Mucins are multifunctional highly glycosylated proteins expressed by the female reproductive tract. Differential expression of MUC1 and MUC15 has been shown in trophoblast. This study was undertaken to establish the distribution of mucin(s) in cytotrophoblast cell cultures using anti-bovine submaxillary mucin (BSM) and to investigate the possibility of
Zanka, Bojić-Trbojević, Milica, Jovanović Krivokuća, Nikola, Kolundžić, Miloš, Petronijević, Svetlana, Vrzić-Petronijević, Snežana, Golubović, Ljiljana, Vićovac   +6 more
openaire   +2 more sources

Aptamer-Gated Ion Channel for Ultrasensitive Mucin 1 Detection

Analytical Chemistry, 2021
Detection of cancer markers is important for early diagnosis and timely treatment of cancer. In this study, we fabricated a tailorable gold nanofilm-anodized aluminum oxide (Au-AAO) ion channel through nanoparticle self-assembly and proposed a highly sensitive and selective Mucin 1 (MUC1) detection method.
Mengying Pan, Jiarong Cai, Si Li, Liguang Xu, Wei Ma, Chuanlai Xu, Hua Kuang   +6 more
openaire   +2 more sources

MUC‐1 mucin expression in invasive areas of intraductal papillary mucinous tumors of the pancreas

Pathology International, 1998
The expression of MUC‐1 mucin (membrane‐associated mucin) and MUG2 much (secretory mucin) were immunohistochemically examined in 46 invasive ductal carcinomas (IDC) and 16 intraductal papillary mucinous tumors (IPMT) of the pancreas. lntraductal papillary mucinous tumors usually reveal expansive growth.
S, Yonezawa, M, Taira, M, Osako, M, Kubo, S, Tanaka, K, Sakoda, S, Takao, T, Aiko, M, Yamamoto, T, Irimura, Y S, Kim, E, Sato   +11 more
openaire   +2 more sources

Mucinous Cells in Type 1 Pulmonary Congenital Cystic Adenomatoid Malformation as Mucinous Bronchioloalveolar Carcinoma Precursors

American Journal of Surgical Pathology, 2007
Type 1 congenital cystic adenomatoid malformation (CCAM), the most frequent malformation of the lung, is the only type to present intracystic mucinous cell clusters, which may form beyond the cysts extracystic mucinous proliferation resembling mucinous bronchioloalveolar carcinomas (BACs).
Lantuejoul, Sylvie, Nicholson, Andrew, Sartori, Giuliana, Piolat, Christian, Danel, Claire, Brabencova, Eva, Goldstraw, Peter, Brambilla, Elisabeth, Rossi, Giulio   +8 more
openaire   +3 more sources

MUC-1 Mucin Protein Expression in B-cell Lymphomas

Applied Immunohistochemistry & Molecular Morphology, 2003
We have recently shown that MUC1, mapped to the chromosomal band 1q21, is rearranged or amplified in 15% of B-cell lymphomas and that rearrangement led to over-expression of MUC-1 mucin in a case of diffuse large B-cell lymphoma (DLBCL). To determine the incidence of MUC-1 mucin expression and its clinical significance in B-cell lymphomas, we ...
Julie, Teruya-Feldstein, Gerard B, Donnelly, Andre, Goy, Abhijith, Hegde, Gouri, Nanjangud, Jing, Qin, Howard, Thaler, Frederic, Gilles, Vadim G, Dyomin, Kenneth O, Lloyd, Andrew D, Zelenetz, Jane, Houldsworth, R S K, Chaganti   +12 more
openaire   +2 more sources

Mucin-1-related T cell infiltration in colorectal carcinoma

Cancer Immunology, Immunotherapy, 1996
Mucins (MUC) are highly glycosylated molecules widely expressed on epithelia of different origins, including colonic mucosa. Altered glycosylation processes in tumour cells result in the exposure of normally cryptic peptide epitopes, which may then be recognized as tumour-specific antigens.
Mulder, W. M.C., Stukart, M. J., De Windt, E., Wagstaff, J., Scheper, R. J., Bloemena, E.   +5 more
openaire   +4 more sources

Tim-1 Mucin Domain-Mutant Mice Display Exacerbated Atherosclerosis

Atherosclerosis, 2019
Increasing  evidence  has  shown  that  immune checkpoint  molecules  of  the  T-cell  immunoglobulin  and  mucin  domain (TIM) family are associated with diverse  physiologic  and pathologic  pro- cesses. Previous studies investigating TIM-1 in atherosclerosis using anti- TIM-1  antibodies  have  yielded  contradictory  results.
Douna, H., Smit, V., Puijvelde, G. van, Binder, C., Bot, I., Kuchroo, V., Lichtman, A., Kuiper, J., Foks, A.   +8 more
openaire   +2 more sources

Adherence of Shigella dysenteriae 1 to Human Colonic Mucin

Current Microbiology, 2001
The pathogenic potential of Shigella is correlated with the ability of the organism to invade and multiply within the cells of colonic epithelium. Although invasion is the ultimate event, a preceding step is adherence. Shigella dysenteriae 1 preferentially adhered to colonic mucin and not to small intestinal mucin.
P S, Sudha, H, Devaraj, N, Devaraj
openaire   +2 more sources

Designer Tridentate Mucin 1 Aptamer for Targeted Drug Delivery

Journal of Pharmaceutical Sciences, 2012
A single-stranded DNA aptamer (APT) capable of targeting mucin 1 (MUC1) extracellular protein was modified to increase its drug delivery specificity toward MUC1 overexpressing cancer cell line, MCF7. The active targeting region of APT was truncated and variable repeats (one, two, or three) of this sequence were synthesized. An aptamer formed from three
Tan, L., Gee Neoh, K., Kang, E.-T., Choe, W.-S., Su, X.   +4 more
openaire   +2 more sources

Intestinal mucin is a chaperone of multivalent copper

Cell, 2022
Deborah Fass
exaly