Results 131 to 140 of about 109,953 (344)

Molecular analysis of TCGA breast cancer histologic types

open access: yesCell Genomics, 2021
Summary: Breast cancer is classified into multiple distinct histologic types, and many of the rarer types have limited characterization. Here, we extend The Cancer Genome Atlas Breast Cancer (TCGA-BRCA) dataset with additional histologic type annotations
Aatish Thennavan   +11 more
doaj  

Discrepancy Between Radiographic and Pathological Response Assessment in Neoadjuvant Treatment for Pancreatic Cancer: A Comparison Between Neoadjuvant Chemotherapy and Neoadjuvant Chemoradiotherapy

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
This study investigated the association between radiographic and pathological response assessments among patients with pancreatic cancer receiving neoadjuvant chemotherapy and neoadjuvant chemoradiotherapy. The present study revealed that discrepancies between radiographic and histological responses may differ according to the type of therapy ...
Satoru Miyahara   +8 more
wiley   +1 more source

Phase Ib study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis

open access: yesHepatology, EarlyView., 2022
Phase 1b study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis. Abstract Background and Aims We evaluated the efficacy and safety of the antiangiogenic tyrosine kinase inhibitor anlotinib plus TQB2450, a programmed death‐ligand 1 inhibitor in pretreated advanced biliary tract cancers (BTCs ...
Jun Zhou   +13 more
wiley   +1 more source

Peculiarities of mucinous colorectal carcinoma [PDF]

open access: bronze, 1985
H C Umpleby   +2 more
openalex   +1 more source

Primary Signet-Ring Carcinoma (Linitus Plastica) of the Colorectum presenting as Subacute Intestinal Obstruction [PDF]

open access: yes, 2012
Primary Signet-ring cell carcinoma (Linitus Plastica) of the colon and rectum is a rare form of adenocarcinoma of the large intestine and has been reported to have an extremely poor prognosis. We report a case of Primary Signet-ring cell carcinoma of the
Jagtap, SS   +4 more
core  

Integration of Cholesterol Oxidase‐Based Biosensors on a Smart Contact Lens for Wireless Cholesterol Monitoring from Tears

open access: yesAdvanced Intelligent Systems, EarlyView.
The combination of a parity‐time symmetry wireless technology with a cholesterol sensor integrated into a smart contact lens enables high‐sensitivity cholesterol sensing at low concentration. Cholesterol plays a critical role in physiological functions, but elevated levels increase the risk of cardiovascular disease.
Yang Cui   +4 more
wiley   +1 more source

Macrophage‐derived MLKL in alcohol‐associated liver disease: Regulation of phagocytosis

open access: yesHepatology, EarlyView., 2022
EtOH causes leaky gut allowing bacteria and PAMPs into the liver, resulting in hepatic inflammation and injury. We demonstrate that LPS induces STAT1‐mediated expression and phosphorylation of MLKL in macrophages and identify a novel function that myeloid MLKL translocates to phagosomes and lysosomes and regulates phagocytosis, which contributes to the
Xiaoqin Wu   +16 more
wiley   +1 more source

Undetermined Ruptured Low‐Grade Appendiceal Mucinous Neoplasm Following High‐Energy Blunt Abdominal Trauma Requiring Emergency Laparotomy

open access: yesClinical Case Reports
Blunt abdominal trauma causing intraperitoneal injury and/or bleeding can be life‐threatening, requiring immediate intervention. Diagnosing these cases can be challenging, especially when pre‐existing conditions are involved.
Ippei Matsuo   +9 more
doaj   +1 more source

Extracellular Vesicles in Calcium Oxalate Nephrolithiasis: Emerging Biomarkers and Therapeutic Potential

open access: yesAdvanced NanoBiomed Research, EarlyView.
Kidney stones cause significant pain and healthcare costs. Current prediction, diagnosis, and treatment options are limited. Extracellular vesicles (EVs), rich in proteins, lipids, and nucleic acids, offer a promising solution. This review explores the roles of EVs in kidney stone management, highlighting their potential as biomarkers and therapeutic ...
Wang Zhu   +3 more
wiley   +1 more source

Proteogenomic characterization of cholangiocarcinoma

open access: yesHepatology, EarlyView., 2022
Proteogenomic characterization of cholangiocarcinoma with therapeutic strategies Abstract Background and Aims Cholangiocarcinoma (CCA) is a highly heterogeneous cancer with limited understanding and few effective therapeutic approaches. We aimed at providing a proteogenomic CCA characterization to inform biological processes and treatment ...
Mengjie Deng   +18 more
wiley   +1 more source

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