Results 61 to 70 of about 153,435 (385)
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Pseudomyxoma Peritonei: Radiological Aspect
International Journal of Anatomy Radiology and Surgery, 2018 Pseudomyxoma peritonei is one of the complications of mucin secreting tumours arising from appendix or ovary. Malignancy of biliary tree, urachus and colon may also have similar presentation.
Ashish Garg +4 more
doaj +1 more source
Neuroendocrine Tumors of the Breast: Single-Center Experience
European Journal of Breast Health, 2022 Objective:Breast carcinomas with neuroendocrine (NE) differentiation are extremely rare. The aim was to discuss breast cancer cases with NE differentiation in the light of World Health Organization 2019 classification and literature information.Material ...
Bermal Hasbay +2 more
doaj +1 more source
TREX1, a predator for treating MSI‐H tumors?
Molecular Oncology, EarlyView.Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya +2 more
wiley +1 more source
대한영상의학회지, 2018 Colon cancer arising in a colonic diverticulum is very rare. There are only a few reported cases of colon cancer associated with a diverticulum. Of these reported cases, only a few are those of a mucinous adenocarcinoma. Here, we report a case of an 82-
Goun Choi +4 more
doaj +1 more source
A Novel Case of Recurrent Mucinous Borderline Ovarian Tumor: Early Relapse and Fatal Outcome
Reports, 2022 Unlike ovarian carcinomas, borderline ovarian tumors (BOTs) are associated with a favorable prognosis: their recurrence rate is around 5–7%, and the survival rate is more than 97% when diagnosed early. There are only a few reports of recurrence and fatal
Kyoko Nakagawa +7 more
doaj +1 more source
Periacinar clefting and p63 immunostaining in prostatic intraepithelial neoplasia and prostatic carcinoma [PDF]
, 2006 The aim of the present study was to correlate the presence and extent of retraction clefting and the expression of p63 in neoplastic glands and glands with prostatic intraepithelial neoplasia (PIN) in needle core biopsies.
Belicza, Mladen +5 more
core +1 more source
Metformin treatment for diabetes mellitus correlates with progression and survival in colorectal carcinoma [PDF]
, 2020 BACKGROUND: Diabetes mellitus is unfavorably associated with cancer risk. The purpose of this multi-disciplinary project was to evaluate a possible association of diabetes mellitus and other comorbidities and their treatment with progression of ...
Brown, Robert E. +10 more
core +1 more source
Risk of the Watch-and-Wait Concept in Surgical Treatment of Intraductal Papillary Mucinous Neoplasm [PDF]
, 2021 Christine Tjaden +15 more
openalex +1 more source
Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity
Molecular Oncology, EarlyView.Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek +2 more
wiley +1 more source