Results 101 to 110 of about 362,300 (406)

PET/CT incidental detection of second tumor in patients investigated for pancreatic neoplasms [PDF]

, 2018
Positron Emission Tomography/computed tomography (PET/CT) is an imaging technique which has a role in the detection and staging malignancies (both in first diagnosis and follow-up).
Bissoli, Sergio, Fantin, Alberto, Moletta, Lucia, Passuello, Nicola, Sperti, Cosimo, Valmasoni, Michele   +5 more
core   +2 more sources

Digitonin‐Loaded Nanoscale Metal–Organic Framework for Mitochondria‐Targeted Radiotherapy‐Radiodynamic Therapy and Disulfidptosis

Advanced Materials, EarlyView.
A mitochondria‐targeted cationic nanoscale metal organic framework shows strong radiotherapy‐radiodynamic therapy effects and selectively releases digitonin in acidic tumor microenvironments to induce disulfidptosis of cancer cells and downregulate immune checkpoints in cancer and T cells, thereby eliciting strong antitumor immunity to effectively ...
Wenyao Zhen, Yingjie Fan, Tomas Germanas, Langston Tillman, Jinhong Li, Abigail L. Blenko, Ralph R. Weichselbaum, Wenbin Lin   +7 more
wiley   +1 more source

Prognosis of resected invasive mucinous adenocarcinoma compared with the IASLC histologic grading system for invasive nonmucinous adenocarcinoma: Surgical database study in the TKIs era in Korea

Thoracic Cancer, Volume 13, Issue 23, Page 3310-3321, December 2022., 2022
Patients with Inavsive mucinous adenocarcinoma (IMA) have better Recurrence‐free surviva (RFS) than those with International Association for the Study of Lung Cancer (IASLC) grade 3 lung adenocarcinoma. Patients with IMA have similar RFS to those with IASLC grade 2 lung adenocarcinoma.
Wongi Woo, Young Ho Yang, Yoon Jin Cha, Duk Hwan Moon, Hyo Sup Shim, Arthur Cho, Bong Jun Kim, Ha Eun Kim, Byung Jo Park, Jin Gu Lee, Dae Joon Kim, Hyo Chae Paik, Sungsoo Lee, Chang Young Lee   +13 more
wiley   +1 more source

H&E-based Computational Biomarker Enables Universal EGFR Screening for Lung Adenocarcinoma [PDF]

arXiv, 2022
Lung cancer is the leading cause of cancer death worldwide, with lung adenocarcinoma being the most prevalent form of lung cancer. EGFR positive lung adenocarcinomas have been shown to have high response rates to TKI therapy, underlying the essential nature of molecular testing for lung cancers.
arxiv  

Multifocal High-Grade Pancreatic Precursor Lesions: A Case Series and Management Recommendations [PDF]

, 2019
Background: The risk of developing invasive cancer in the remnant pancreas after resection of multifocal high-grade pancreatic precursor lesions is not well known.
Carr, Rosalie A., Roch, Alexandra M., Schmidt, Christian Max, Soufi, Mazhar, Wu, Howard H., Yip-Schneider, Michele T.   +5 more
core   +1 more source

A Dynamic Double‐Flow Gut‐On‐Chip Model for Predictive Absorption Studies In Vitro

Advanced Materials Technologies, EarlyView.
This study presents a novel millifluidic gut‐on‐chip model using the MIVO® device to replicate human intestinal conditions. Dynamic co‐culture of CaCo‐2 and HT‐29 cells accelerates differentiation, modulates mucus thickness, and enhances barrier function.
Maria Elisabetta Federica Palamà, Maurizio Aiello, Gergő Borka, Jacopo Furci, Ilaria Parodi, Giuseppe Firpo, Silvia Scaglione   +6 more
wiley   +1 more source

Modifying factors of PD‐L1 expression on tumor cells in advanced non‐small‐cell lung cancer

Thoracic Cancer, Volume 13, Issue 23, Page 3362-3373, December 2022., 2022
Programmed death ligand‐1 (PD‐L1) is an essential biomarker guiding treatment in nononcogene addicted advanced lung adenocarcinoma, and many factors may impact its reproducibility and performance. This study demonstrated an increased probability of identifying PD‐L1‐positive samples in poorly differentiated, solid predominant, and EGFR wild‐type tumors.
Alejandro Avilés‐Salas, Diana Flores‐Estrada, Luis Lara‐Mejía, Rodrigo Catalán, Graciela Cruz‐Rico, Mario Orozco‐Morales, David Heredia, Laura Bolaño‐Guerra, Pamela Denisse Soberanis‐Piña, Edgar Varela‐Santoyo, Andrés F. Cardona, Oscar Arrieta   +11 more
wiley   +1 more source

Convolution Neural Networks for diagnosing colon and lung cancer histopathological images [PDF]

arXiv, 2020
Lung and Colon cancer are one of the leading causes of mortality and morbidity in adults. Histopathological diagnosis is one of the key components to discern cancer type. The aim of the present research is to propose a computer aided diagnosis system for diagnosing squamous cell carcinomas and adenocarcinomas of lung as well as adenocarcinomas of colon
arxiv  

Fully Automatic Deep Learning Framework for Pancreatic Ductal Adenocarcinoma Detection on Computed Tomography [PDF]

lves, N.; Schuurmans, M.;Litjens, G.; Bosma, J.S.; Hermans, J.;Huisman, H. Fully Automatic DeepLearning Framework for PancreaticDuctal Adenocarcinoma Detection onComputed Tomography.Cancers2022,14, 376, 2021
Early detection improves prognosis in pancreatic ductal adenocarcinoma (PDAC) but is challenging as lesions are often small and poorly defined on contrast-enhanced computed tomography scans (CE-CT). Deep learning can facilitate PDAC diagnosis, however current models still fail to identify small (<2cm) lesions.
arxiv  

Periacinar clefting and p63 immunostaining in prostatic intraepithelial neoplasia and prostatic carcinoma [PDF]

, 2006
The aim of the present study was to correlate the presence and extent of retraction clefting and the expression of p63 in neoplastic glands and glands with prostatic intraepithelial neoplasia (PIN) in needle core biopsies.
Belicza, Mladen, Cviko, Aida, Krušlin, Božo, Odak, Ljubica, Tomas, Davor, Čupić, Hrvoje   +5 more
core   +1 more source