Results 161 to 170 of about 370,037 (337)

Laryngopharyngeal Reflux: The Impact of Obesity

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT This article provides an overview of gastro‐esophageal (GERD) and laryngopharynegal (LPRD) reflux diseases in the context of obesity as a confounding entity. A detailed review of the clinical presentation, pathogenesis, diagnosis, and treatment of laryngopharyngeal reflux disease may be found elsewhere.
Abdul Latif H. Hamdan   +2 more
wiley   +1 more source

Causal Analysis Between Gut Microbes, Aging Indicator, and Age‐Related Disease, Involving the Discovery and Validation of Biomarkers

open access: yesAging Cell, EarlyView.
A comprehensive causal effect analysis was used to illustrate the associations between gut microbiota, aging indicators, and age‐related diseases. This study provides evidence that supports the association between the gut microbiota and aging and highlights the potential of genetic correlation and causal relationship analysis in biomarker discovery ...
Chunrong Lu   +7 more
wiley   +1 more source

mpMRI features of mucinous prostate cancer: two case reports

open access: yesThe Egyptian Journal of Radiology and Nuclear Medicine
Background Mucinous adenocarcinoma of the prostate (MACP) is one of the rarest variants of prostatic neoplasm, with more aggressive behavior than non-mucinous prostatic cancer.
Giuseppe Chiacchio   +10 more
doaj   +1 more source

Protein tyrosine phosphatases as emerging targets for cancer immunotherapy

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Contemporary strategies in cancer immunotherapy, despite remarkable success, remain constrained by inherent limitations such as suboptimal patient responses, the emergence of drug resistance, and the manifestation of pronounced adverse effects. Consequently, the need for alternative strategies for immunotherapy becomes clear.
Zihan Qu, Jiajun Dong, Zhong‐Yin Zhang
wiley   +1 more source

Cystic Lesions of the Pancreas [PDF]

open access: yes, 2014
With the increasing use of abdominal imaging, cystic lesions of the pancreas are being more frequently detected. These lesions may carry a significant premalignant potential.
Azzopardi, Neville
core  

A clinicopathologic study of mucinous adenocarcinoma of the stomach [PDF]

open access: bronze, 2001
Hideki Kawamura   +8 more
openalex   +1 more source

Polo‐Like Kinase 1 Expression in Colorectal Cancer: Association With RAS Mutations

open access: yesCancer Science, EarlyView.
PLK1 expression may serve as a biomarker for adjuvant chemotherapy resistance in CRC. This study focused on the relationship between PLK1 expression and RAS mutation, which has been reported to be highly sensitive to PLK1 inhibitors. RAS mutation with high PLK1 expression predicts poorer survival in adjuvant‐treated CRC patients.
Yasushi Tanaka   +9 more
wiley   +1 more source

Ligand‐Based CAR‐T Cells Targeting EGFR Exhibit Favorable Antitumor Effects Against Gynecologic Malignancies

open access: yesCancer Science, EarlyView.
Wide variety of gynecologic malignancies express EGFR at high rates. Memory‐rich EGFR CAR‐T cells can be made by piggyBac‐mediated gene transfer with immature dendritic cells and EGFR protein. Ligand‐based EGFR CAR‐T cells have robust antitumor effects against gynecologic malignancies in vivo and in vitro.
Manaka Shinagawa   +16 more
wiley   +1 more source

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