Nanomedicine for Oral Delivery: Strategies to Overcome the Biological Barriers
Oral delivery is a preferred administration route for many clinical applications, valued for its strong patient compliance. In this review, how nanoparticles are engineered and deployed to overcome the gastrointestinal barriers that impede clinical translation of oral delivery formulations is examined.
Luke J. Kubiatowicz +5 more
wiley +1 more source
Composite HPMC and sodium alginate based buccal formulations for nicotine replacement therapy [PDF]
Smoking cessation is of current topical interest due to the significant negative health and economic impact in many countries. This study aimed to develop buccal films and wafers comprising HPMC and sodium alginate (SA) for potential use in nicotine ...
Ayensu +37 more
core +1 more source
ABSTRACT Introduction Thickening fluids in routine care of patients with Oropharyngeal dysphagia (OD) can improve swallow safety but may be counteracted by reduced palatability, enjoyment, embarrassment, and isolation related to drinking thickened fluids (TFs).
Natascha Ullrich +6 more
wiley +1 more source
Enhancement and inhibition effects on the corneal permeability of timolol maleate: polymers, cyclodextrins and chelating agents [PDF]
This study investigates how both bioadhesive polymers (chitosan, hyaluronic acid and alginate) and permeability enhancers (ethylene glycol- bis(2-aminoethylether)- N, N, N', N'- tetraacetic acid (EGTA) and hydroxypropyl-ß-cyclodextrin) influence the ...
Khutoryanskiy, Vitaliy V. +3 more
core +1 more source
Design of binary polymeric systems containing ɩ-carrageenan and hydroxypropylcellulose for use in cataract surgery. [PDF]
This study describes the design and characterisation of the rheological and mechanical properties of binary polymeric systems composed of 2-Hydroxypropylcellulose and ɩ-carrageenan, designed as ophthalmic viscoelastic devices (OVDs).
Andrews, Gavin P. +2 more
core +1 more source
Advancements in Alginate‐Based Biomaterials for Enhanced Skin Regeneration: A Comprehensive Review
Alginate, a naturally occurring polysaccharide composed of β‐d‐mannuronate (M) and α‐l‐guluronate (G), has attracted widespread attention for skin regeneration applications due to its exceptional biocompatibility, biodegradability, and tunable physicochemical properties. Beyond its traditional role in maintaining a moist wound environment and providing
Nasrul Wathoni +8 more
wiley +1 more source
Pterodon pubescens Mucoadhesive Film for dental use. ABSTRACT Periodontal diseases involve infectious and inflammatory processes that affect oral tissues. Extracts from Pterodon pubescens Benth (sucupira) have demonstrated antinociceptive, anti‐inflammatory, anti‐edematogenic, and antiplatelet effects, highlighting their therapeutic potential for ...
Mariana Cecchetto Figueiredo +13 more
wiley +1 more source
Polymeric gels for intravaginal drug delivery [PDF]
This document is the Accepted Manuscript version of the following article: Michael T. Cook, and Marc b. Brown, ‘Polymeric gels for intravaginal drug delivery’, Journal of Controlled Release, Vol. 270: 145-157, January 2018. Under embargo until 6 December
Brown, Marc, Cook, Michael
core +2 more sources
Spore exines increase vitamin D clinical bioavailability by mucoadhesion and bile triggered release
Alberto Diego‐Taboada +14 more
openalex +2 more sources
Soluplus solutions as thermothickening materials for topical drug delivery. [PDF]
Soluplus is a pharmaceutical excipient used primarily in the manufacture of solid dispersions. The polymer also exhibits interesting rheology in aqueous solution, increasing in viscosity as the solution is warmed.
Abou Shamat, Mohamad, Cook, Michael
core +2 more sources

