Results 1 to 10 of about 17,478 (246)

Mucoadhesive Marine Polysaccharides

Marine Drugs, 2022
Mucoadhesive polymers are of growing interest in the field of drug delivery due to their ability to interact with the body’s mucosa and increase the effectiveness of the drug.
Yermak Irina
exaly   +6 more sources

Synthesis and functionalization of mucoadhesive mesoporous silica particles containing diphenhydramine for treatment of aphthous ulcers [PDF]

BioImpacts, 2023
Introduction: Medications used to treat oral ulcers include corticosteroids, anesthetics, and antihistamines. These can be used as gels, mouthwashes, pastes, ointments, etc.
Azadeh Vaezi Moghaddam, Seyed Alireza Mortazavi, Farzad Kobarfard, Reza Bafkary, Behzad Darbasizadeh   +4 more
doaj   +1 more source

Development, Characterization and Pharmacokinetic Profile of Chitosan-Sodium Tripolyphosphate Nanoparticles Based Drug Delivery Systems for Curcumin [PDF]

Advanced Pharmaceutical Bulletin, 2021
Purpose: This study aimed to provide the method of preparation, characterization of curcumin-loaded chitosan-sodium tripolyphosphate (NaTPP) nanoparticle, and evaluate its pharmacokinetic profiles.
Wawaimuli Arozal, Melva Louisa, Deni Rahmat, Priska Chendrana, Ni Made Dwi Sandhiutami   +4 more
doaj   +1 more source

Studies on Jackfruit–Okra Mucilage-Based Curcumin Mucoadhesive Tablet for Colon Targeted Delivery

Frontiers in Pharmacology, 2022
The present work investigates a blend of jack fruit mucilage (JFM) and okra mucilage (OKM) as promising mucoadhesive carriers for colon-specific delivery of a curcumin (CMN)-loaded mucoadhesive tablet (CMT) formulation.
Pallavi Kurra, Kishore Narra, Raha Orfali, Srinivasa Babu Puttugunta, Shah Alam Khan, Dhanalekshmi Unnikrishnan Meenakshi, Arul Prakash Francis, Syed Mohammed Basheeruddin Asdaq, Mohd. Imran   +8 more
doaj   +1 more source

Amoxicillin and Clarithromycin Mucoadhesive Delivery System for Helicobacter pylori Infection in a Mouse Model: Characterization, Pharmacokinetics, and Efficacy

Pharmaceutics, 2021
Helicobacter pylori is the main pathogen responsible for gastric ulcers and a predisposing factor of stomach cancer. Although current treatment is usually successful, it requires high doses and frequent administration.
Isabel Villegas, María Ángeles Rosillo, Catalina Alarcón-de-la-Lastra, Victoria Vázquez-Román, Maria Llorente, Susana Sánchez, Ana Gloria Gil, Pilar Alcalde, Esther González, Elisabet Rosell, Carles Nieto, Francisco Fernandez-Campos   +11 more
doaj   +1 more source

Effect of Green Tea Mucoadhesive Paste on Recurrent Aphthous Stomatitis Treatment [PDF]

Journal of Mashhad Dental School, 2020
Introduction: Recurrent aphthous stomatitis (RAS) is a common oral disease, which presents as painful and recurrent single or multiple ulcers in the oral mucosa.
Atekeh Movaghari pour, Payam Khazaeli, Nazanin Kamyab, Mahsa Pourzamani, Fatemehsadat Moeinzadeh, Mahmood Sheikh Fathollahi   +5 more
doaj   +1 more source

Intranasal Microemulsion as an Innovative and Promising Alternative to the Oral Route in Improving Stiripentol Brain Targeting

Pharmaceutics, 2023
Stiripentol (STP) is a new-generation antiepileptic only available for oral administration. However, it is extremely unstable in acidic environments and undergoes gastrointestinal slow and incomplete dissolution.
Sara Meirinho, Márcio Rodrigues, Adriana O. Santos, Amílcar Falcão, Gilberto Alves   +4 more
doaj   +1 more source

Formulation and Optimization of Sodium Alginate Polymer Film as a Buccal Mucoadhesive Drug Delivery System Containing Cetirizine Dihydrochloride

Pharmaceutics, 2021
Currently, pharmaceutical companies are working on innovative methods, processes and products. Oral mucoadhesive systems, such as tablets, gels, and polymer films, are among these possible products.
Krisztián Pamlényi, Katalin Kristó, Orsolya Jójárt-Laczkovich, Géza Regdon   +3 more
doaj   +1 more source

Intranasal Administration of Dolutegravir-Loaded Nanoemulsion-Based In Situ Gel for Enhanced Bioavailability and Direct Brain Targeting

Gels, 2023
Dolutegravir’s therapeutic effectiveness in the management of neuroAIDS is mainly limited by its failure to cross the blood–brain barrier. However, lipid-based nanovesicles such as nanoemulsions have demonstrated their potential for the brain targeting ...
Anroop B. Nair, Sunita Chaudhary, Shery Jacob, Dhwani Patel, Pottathil Shinu, Hiral Shah, Ankit Chaudhary, Bandar Aldhubiab, Rashed M. Almuqbil, Ahmed S. Alnaim, Fatemah Alqattan, Jigar Shah   +11 more
doaj   +1 more source

Effects of Sucrose Palmitate on the Physico-Chemical and Mucoadhesive Properties of Buccal Films

Molecules, 2020
In our current research, sucrose palmitate (SP) was applied as a possible permeation enhancer for buccal use. This route of administration is a novelty as there is no literature on the use of SP in buccal mucoadhesive films.
András Kelemen, Bálint Katona, Szilvia Módra, Zoltán Aigner, István Sebe, Klára Pintye-Hódi, Romána Zelkó, Géza Regdon, Katalin Kristó   +8 more
doaj   +1 more source