Results 31 to 40 of about 17,478 (246)

Treatment of oral lichen planus with mucoadhesive mycophenolate mofetil patch: A randomized clinical trial

open access: yesClinical and Experimental Dental Research, 2020
Objectives Oral lichen planus (OLP) is a chronic inflammatory disease of unknown etiology which is known as a premalignant disease. A complete cure has not been found for this condition.
Negin Samiee   +3 more
doaj   +1 more source

Mucoadhesive Buccal Film of Estradiol for Hormonal Replacement Therapy: Development and In-Vivo Performance Prediction

open access: yesPharmaceutics, 2022
The age-related loss of circulating estrogen that occurs during the menopausal transition manifests itself through a variety of symptoms including vasomotor (hot flushes and night sweats), genito-urinary syndrome (vaginal dryness and urinary symptoms ...
Sadikalmahdi Abdella   +4 more
doaj   +1 more source

Experimental Design Approach for the Formulation of Controlled Release Buccal Bilayer Tablets of Carvedilol

open access: yesJournal of Integrated Health Sciences, 2018
Introduction: The absolute bioavailability of carvedilol is ~25% - 35% even though it rapidly and extensively absorbed following oral administration due to a significant degree of presystemic metabolism.
Vinodkumar D. Ramani   +4 more
doaj   +1 more source

Physicochemical Properties of African Catfish Mucus and Its Effect on the Stability of Soya Milk Emulsions

open access: yesApplied Sciences, 2020
Mucus, a waste product produced when African catfish undergoes stress, has lubricating effects and could be a potential emulsifier. Emulsions are thermodynamically unstable; researchers have documented synthetic bio-polymers as emulsifiers, but its ...
Adebanji Joseph Olasupo Oluwole   +2 more
doaj   +1 more source

A Comprehensive Review on Mucoadhesive Drug Delivery [PDF]

open access: yes, 2022
The two major problems in the development of new drugs are low aqueous solubility and low oral bioavailability. Although, drug delivery via oral route is most preferred for years but it also has some drawbacks.
Agrawal, Abhinav   +2 more
core   +1 more source

Kompleks Polielektrolit Kitosan-Xanthan sebagai Matriks Sediaan Mukoadhesif

open access: yesPharmaceutical Sciences and Research, 2017
Mucoadhesive dosage form is a pharmaceutical dosage form with prolonged gastric residence time which can increase bioavailability of drugs. An excipient with suitable swelling and bioadhesive characteristics plays important role to obtain good ...
Kurnia Sari Setio Putri   +2 more
doaj   +1 more source

Intranasal Delivery of Darunavir-Loaded Mucoadhesive In Situ Gel: Experimental Design, In Vitro Evaluation, and Pharmacokinetic Studies

open access: yesGels, 2022
The clinical efficacy of antiretroviral therapy in NeuroAIDS is primarily limited by the low perfusion of the drug to the brain. The objective of the current investigation was to design and develop an in situ mucoadhesive gel loaded with darunavir to ...
Anroop B. Nair   +10 more
doaj   +1 more source

The Preparation and Evaluation of Cyanocobalamin Mucoadhesive Sublingual Tablets

open access: yesPharmaceuticals, 2023
Cobalamin (vitamin B12), an essential vitamin with low oral bioavailability, plays a vital role in cellular functions. This research aimed to enhance the absorption of vitamin B12 using sublingual mucoadhesive tablets by increasing the residence time of ...
Anwar Ma’ali   +5 more
doaj   +1 more source

Development of probiotic orodispersible tablets using mucoadhesive polymers for buccal mucoadhesion

open access: yesDrug Development and Industrial Pharmacy, 2020
Probiotic bacteria, such as different lactobacilli strains, have successfully been used to treat gingivitis and periodontitis or caries. By formulating probiotics as orodispersible tablet (ODT), the benefits of this dosage form could be utilized. Without any further measures, the probiotic bacteria will be eliminated too fast from the intended site of ...
Anja Hoffmann   +2 more
openaire   +2 more sources

Mucoadhesive Nanoparticles Enhance the Therapeutic Effect of Dexamethasone on Experimental Ulcerative Colitis by the Local Administration as an Enema

open access: yesDrug Design, Development and Therapy, 2023
Kai Dong,1,2 Shu-Jing Deng,2 Bin-Yang He,2 Zi-Yang Guo,2 Ze-Lin Guan,2 Xue Leng,2 Rui-Rui Ma,2 Dan-Yang Wang,2 Jian-Feng Xing,2 Cui-Yu You1 1Department of Pharmacy, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, People’s ...
Dong K   +9 more
doaj  

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