Mucoadhesive drug delivery systems
Mucoadhesion is commonly defined as the adhesion between two materials, at least one of which is a mucosal surface. Over the past few decades, mucosal drug delivery has received a great deal of attention. Mucoadhesive dosage forms may be designed to enable prolonged retention at the site of application, providing a controlled rate of drug release for ...
Rahamatullah, Shaikh +4 more
openaire +5 more sources
Mucoadhesion is defined as the adhesion between a mucosal surface and, natural or synthetic, macromolecules. Mucoadhesion is a complex mechanism and it depends intermolecular interactions. The adhesive macromolecules can be part of a pharmaceutical formulation, turning it in a mucoadhesive preparation as well. The mucoadhesion mechanism is divided into
Pinheiro, Joana Rita Leal Brandão
core +4 more sources
Root-Inspired Microneedle Patch With Interlocked Rigid-Soft Architecture for High Tissue-Adaptiveness. [PDF]
A root‐inspired microneedle array patch uses lattice‐based mechanical interlocking to unite rigid microneedles with a flexible substrate. The interlocked rigid–soft architecture improves interfacial bonding, supports stable adhesion on curved and wet tissues under dynamic motion, and provides a versatile platform for robust biointerfacing and future ...
Lee J +9 more
europepmc +2 more sources
Mucoadhesive polymer films for tissue retraction in laparoscopic surgery : ex-vivo study on their mechanical properties [PDF]
This work was financially supported by the Engineering and Physical Sciences Research Council (EPSRC), UK, under Grant EP/H010033/1 and the Royal Society (GJF).Safe and effective manipulation of soft tissue during laparoscopic procedures can be achieved ...
Florence, Gordon John +10 more
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Gastroretentive microparticles for drug delivery applications [PDF]
Many strategies have been proposed to explore the possibility of exploiting gastroretention for drug delivery. Such systems would be useful for local delivery, for drugs that are poorly soluble at higher pH or primarily absorbed from the proximal small ...
Conway, Barbara R +5 more
core +1 more source
MUCOADHESIVE MICROSPHERES: A REVIEW [PDF]
Carrier technology provides an interesting as well as an intelligent approach for the delivery of drug. It offers delivery of drug by coupling the drug to a carrier particle such as microspheres, mucoadhesive microspheres nanoparticles, liposomes, etc.
Aggarwal, Geeta +2 more
core +1 more source
FORMULATION ANDCHARACTERIZATION OF OLANZEPINELOADED MUCOADHESIVE MICROSPHERES [PDF]
Objective: The objective of this research was to formulate and evaluate olanzapine (OLE) mucoadhesive microsphere prepared using carbopol and sodium combination.
Madhuri T Deshmukh, Shrinivas K Mohite
core +3 more sources
Breaking Physiological Barriers in Women's Health: Mucoadhesive and Stimuli-Responsive Nanomaterials. [PDF]
Drug delivery vehicles generated from biomaterials for women's health. In particular, the breast and the reproductive system, including the ovary, uterus, cervix, vagina, and the surrounding tissues, targeted drug delivery. BioRender. ABSTRACT Biomaterials are natural or synthetic molecules that exhibit biocompatibility, biodegradability, or ...
Parsons M +4 more
europepmc +2 more sources
Evaluation of rheological and mucoadhesive properties of selected nasal spray preparations with mometasone furoate [PDF]
Intranasal preparations with mometasone furoate are recognised to be highly efficient and safe in both adults and children. Commercially available nasal sprays are characterised by thixotropic and mucoadhesive properties – factors ensuring effortless ...
Katarzyna Winnicka +3 more
core +1 more source
In vitro of some bfactors affecthng the adhesive strength of mucoadhesive polymers [PDF]
Mucoadhesive durg delivery systems are among novel drug delivery systems that due to their ability to adhere and remain on the mucosal surfaces and a show and sustained release of their drug contect have attracted special attention in recent years.the ...
S.A.R Mortazavi
doaj

