Results 21 to 30 of about 17,478 (246)

Advancement on Sustained Antiviral Ocular Drug Delivery for Herpes Simplex Virus Keratitis: Recent Update on Potential Investigation

open access: yesPharmaceutics, 2020
The eyes are the window to the world and the key to communication, but they are vulnerable to multitudes of ailments. More serious than is thought, corneal infection by herpes simplex viruses (HSVs) is a prevalent yet silent cause of blindness in both ...
Manisha Pandey   +8 more
doaj   +1 more source

Polysaccharide drug delivery systems based on pectin and chitosan [PDF]

open access: yes, 2010
Chitosans and pectins are natural polysaccharides which show great potential in drug delivery systems. Chitosans are a family of strongly polycationic derivatives of poly-N-acetyl-D-glucosamine.
Kok, M. S.   +3 more
core   +3 more sources

Nose-to-brain delivery of insulin nanoparticles for diabetes management: A review

open access: yesBaghdad Journal of Biochemistry and Applied Biological Sciences, 2023
Hyperglycemia and the onset of insulin resistance or deficiency, or both, are the hallmarks of the group of diseases known as diabetes. Ultimately, insulin subcutaneous injection is the most effective treatment for diabetic patients.
Manoj Kumbhare   +2 more
doaj   +1 more source

Formulation, in-vitro characterization and clinical evaluation of curcumin in-situ gel for treatment of periodontitis

open access: yesDrug Delivery, 2017
This study aimed to develop syringeable in-situ curcumin (cur) gel for the treatment of periodontal pockets as well as to evaluate the clinical efficacy of Cur in-situ gel formulation.
Maha M. A. Nasra   +3 more
doaj   +1 more source

Injectable Vaginal Hydrogels as a Multi-Drug Carrier for Contraception

open access: yesApplied Sciences, 2019
Injectable intravaginal hydrogels could deliver drugs systemically without hepatic first pass effect. This paper focuses on the contraceptive function of an injectable temperature-sensitive four-arm star-shaped poly(D,L-lactic-co-glycolic acid)-b-methoxy
Lei Nie   +9 more
doaj   +1 more source

Gastro-retentive oral drug delivery systems: a promising approach for narrow absorption window drugs [PDF]

open access: yesJournal of Advanced Biomedical and Pharmaceutical Sciences, 2019
Drugs with narrow absorption window (NAW) are those drugs that are absorbed from a specific region (most notably first part) of the gastrointestinal tract.
Mohamed Ibrahim   +3 more
doaj   +1 more source

The Impact of Chlorhexidine Mucoadhesive Gel in the Prevention of Ventilator-Associated Pneumonia: A Randomized Clinical Trial [PDF]

open access: yesBulletin of Emergency and Trauma, 2023
Objective: Ventilator-associated pneumonia is the common cause of morbidity and mortality in the intensivecare unit. Due to the antimicrobial effect of chlorhexidine, and the long-lasting result of mucoadhesive drugs,this study aimed to determine the ...
Faramarz Dobakhti   +2 more
doaj   +1 more source

Mucoadhesion: A food perspective

open access: yesFood Hydrocolloids, 2017
The role of mucoadhesion in the perception and sensory characterisation of food products is becoming more apparent. Traditionally, mucoadhesives are used to enhance drug permeability and retention at mucosal membranes in the body, by adherence to a mucosal membrane formed through various interactions between the mucoadhesive and proteins present in the
Sarah L. Cook   +4 more
openaire   +1 more source

Mucoadhesive Gelatin Buccal Films with Propranolol Hydrochloride: Evaluation of Mechanical, Mucoadhesive, and Biopharmaceutical Properties [PDF]

open access: yesPharmaceutics, 2021
This study processes and characterizes propranolol hydrochloride/gelatin mucoadhesive buccal films. Two types of gelatin are used: Gelatin from porcine skin, type A (GA), and gelatin from bovine skin (GB). The influence of gelatin type on mechanical, mucoadhesive, and biopharmaceutical characteristics of buccal films is evaluated.
Marija Jovanović   +5 more
openaire   +6 more sources

Development of Thermoresponsive Hydrogels with Mucoadhesion Properties Loaded with Metronidazole Gel-Flakes for Improved Bacterial Vaginosis Treatment

open access: yesPharmaceutics, 2023
Bacterial vaginosis is an infectious disease that has significantly affected women’s health. Metronidazole has been widely used as a drug for treating bacterial vaginosis.
Andi Dian Permana   +7 more
doaj   +1 more source

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