Results 121 to 130 of about 434,754 (278)

Reconstruction of native cellular microanatomy in a novel bioengineered full thickness human nasal mucosal construct

Journal of Anatomy, EarlyView.
Bioengineered tissue constructs are vital technologies employed in in vitro testing of both fundamental biological principles and industrial screening practices. Current approaches to modelling the nasal mucosa in vitro are not representative and are associated with limitations that impact their reliability and predictive value.
Steven Bradbury, Bethany Dickson, Nicola Curtis, David Bunton, Kirsty Goncalves, Stefan Przyborski   +5 more
wiley   +1 more source

A new paradigm in respiratory hygiene: modulating respiratory secretions to contain cough bioaerosol without affecting mucus clearance

BMC Pulmonary Medicine, 2007
Background Several strategies and devices have been designed to protect health care providers from acquiring transmissible respiratory diseases while providing care. In modulating the physical characteristics of the respiratory secretions to minimize the
Bonilla Gloria, Vega Daniel, Alfaro Henry, Alonso Mauricio, Valle Juan C, Zayas Gustavo, Reyes Miguel, King Malcolm   +7 more
doaj   +1 more source

Controlled, parametric, individualized, 2D and 3D imaging measurements of aerosol deposition in the respiratory tract of healthy human volunteers: in vivo data analysis [PDF]

, 2014
Background: To provide a validation dataset for aerosol deposition modeling, a clinical trial was performed in which the inhalation parameters and the inhaled aerosol were controlled or characterized.Methods: Eleven, healthy, never-smokers, male ...
Caillibotte, Georges, Conway, Joy, Fleming, John, Katz, Ira, Majoral, Caroline, Montesantos, Spyridon, Pichelin, Marine, Tossici-Bolt, Livia   +7 more
core   +1 more source

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

Journal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini, George Hajishengallis, Mike Curtis, Giacomo Baima   +3 more
wiley   +1 more source

Pulmonary diseases induced by ambient ultrafine and engineered nanoparticles in twenty-first century. [PDF]

, 2016
Air pollution is a severe threat to public health globally, affecting everyone in developed and developing countries alike. Among different air pollutants, particulate matter (PM), particularly combustion-produced fine PM (PM2.5) has been shown to play a
Liu, Sijin, Mu, Lina, Xia, Tian, Zhang, Zuo-Feng, Zhu, Yifang   +4 more
core   +2 more sources

The effect of cilia and the mucociliary clearance on successful drug delivery.

Biological and Pharmaceutical Bulletin, 2015
Nasal mucociliary clearance is one of the most important factors affecting nasal delivery of drugs and vaccines. This is also the most important physiological defense mechanism inside the nasal cavity.
S. Gizurarson
semanticscholar   +1 more source

An Update on Invasive Fungal Infections in Solid Organ Transplant Recipients

Transplant Infectious Disease, EarlyView.
ABSTRACT Invasive fungal infections (IFI) remain a significant infection‐related complication in solid organ transplant recipients (SOTRs), the incidence of which has not changed overtime. With a focus on studies and data published after 2019, this narrative review provides an update on the epidemiology and prevention of IFIs in SOTRs and highlights ...
Tina Marinelli, Shahid Husain
wiley   +1 more source

Preclinical Quantitative In Vivo MRI Assessment of Exogenous Surfactant Pulmonary Distribution After Clinically Relevant Intratracheal Delivery

NMR in Biomedicine, Volume 39, Issue 6, June 2026.
Quantitative in vivo contrast‐enhanced UTE MRI enables sensitive and precise mapping of pulmonary surfactant distribution, revealing peripheral localization and homogeneous distal penetration under physiological conditions. Comparison with ex vivo models highlights the role of physiological processes in surfactant retention.
Oumaima Marfouk, Rémy Gérard, Ghalia Kaouane, Lara Leclerc, Noël Pinaud, Michael Fayon, Sophie Périnel‐Ragey, Jérémie Pourchez, Eric Dumas De La Roque, Yannick Crémillieux   +9 more
wiley   +1 more source

Astodrimer sodium nasal spray forms a barrier to SARS-CoV-2 in vitro and preserves normal mucociliary function in human nasal epithelium

Scientific Reports
COVID-19 remains a severe condition for many including immunocompromised individuals. There remains a need for effective measures against this and other respiratory infections, which transmit via virus-laden droplets that reach the nasal or oral mucosae.
Jeremy R. A. Paull, Carolyn A. Luscombe, Aynaz Seta, Graham P. Heery, Michael D. Bobardt, Philippe A. Gallay, Samuel Constant, Alex Castellarnau   +7 more
doaj   +1 more source

Do nasal decongestants relieve symptoms? [PDF]

, 2003
Oral and topical nasal decongestants result in a statistically significant improvement in subjective symptoms of nasal congestion and objective nasal airway resistance in adults' common colds (strength of recommendation [SOR]: A, based on randomized ...
Allen, Ginger, Jankowski, Terry Ann, 1951-, Kelsberg, Gary   +2 more
core