Results 131 to 140 of about 21,273 (241)

Structural Lung Disease in Children and Adolescents With Severe Neurological Disorders

Pediatric Pulmonology, Volume 61, Issue 6, June 2026.
ABSTRACT Background and Objective Children with severe neurological disorders are at risk of secondary respiratory morbidity due to impaired airway clearance and dysphagia, but systematic data on structural lung changes remain scarce. Methods We retrospectively analyzed all clinically indicated chest CT examinations at a tertiary care center (2015–2025)
Daniel A. F. Bernard, Cathrin Dahl, Luca Salhöfer, Anna Pauly, Mathis Steindor, Margarete Olivier, Ulrike Schara‐Schmidt, Matthias Welsner, Bernd Schweiger, Sebastian Zensen, Marcel A. Drews, Johannes Haubold, Michael Forsting, Lale Umutlu, Marcel Opitz, Florian Stehling   +15 more
wiley   +1 more source

The effects of 2100‐MHz radiofrequency radiation on nasal mucosa and mucociliary clearance in rats

, 2015
BackgroundNasal mucociliary clearance has an important role in voiding the airways from inhaled foreign substances. This activity could be disturbed by environmental factors such as radiofrequency radiation.
Ethem Erdal Samim, Arin Tomruk, Göknur Güler Öztürk, Arzu Tüzüner, ATİLLA, PERGİN, Tuzuner, Arzu, TOMRUK, ARIN, Muftuoglu, Sevda, Ozturk, Goknur Guler, Şule Demirci, Koca, Gokhan, Korkmaz, Meliha, Emine Aydın, ÖZGÜR BÜYÜKATALAY, ELÇİN, Gökhan Koca, Nesrin Seyhan, Aydin, Emine, Meliha Korkmaz, Seyhan, Nesrin, Samim, Ethem Erdal, Aydogan, Filiz, Demirci, Sule, Filiz Aydoğan, Pergin Atilla, Elçin Özgür, Sevda Müftüoğlu   +25 more
core   +1 more source

Effect of inhaled anticholinergics on bronchial secretions: a systematic review

Frontiers in Physiology
BackgroundInhaled anticholinergics are commonly used in chronic respiratory diseases with the intention of reducing bronchial secretions in addition to their bronchodilatory effects.
Leonardo Arzayus-Patiño, Leonardo Arzayus-Patiño, José Julián Bernal-Sanchez, José Julián Bernal-Sanchez, Valeria Pérez-Hortua, Valeria Pérez-Hortua, Esther Cecilia Wilches-Luna, Esther Cecilia Wilches-Luna, Vicente Benavides-Cordoba   +8 more
doaj   +1 more source

The Relationship Between Structural and Functional Pulmonary Status and Quality of Life in Children With Primary Ciliary Dyskinesia

Pediatric Pulmonology, Volume 61, Issue 6, June 2026.
ABSTRACT Introduction Primary ciliary dyskinesia (PCD) is a genetic disorder characterized by impaired mucociliary clearance, leading to recurrent airway infections and bronchiectasis. Monitoring disease progression requires both functional and structural assessments of the lungs.
Nesibe Hatun Sarıhan, Sinem Can Oksay, Sabriye Gülçin Bozbeyoğlu, Saniye Girit   +3 more
wiley   +1 more source

Effects of Prednisone on Mucociliary Clearance in a Murine Model

, 2012
All transplant patients are at increased risk of developing pulmonary infections, a significant cause of morbidity and mortality. Immunosuppressants increase the incidence of lung infection by acting not only directly on the inflammatory cells, but also ...
Jatene, F.B., Oliveira-Braga, K.A., Correia, A.T., Nepomuceno, N.A., Pêgo-Fernandes, P.M.   +4 more
core   +1 more source

Novel Therapeutics for Chronic Obstructive Pulmonary Disease: From Empirical Bronchodilation to Precision Medicine

Respirology, Volume 31, Issue 6, Page 561-577, June 2026.
ABSTRACT Chronic obstructive pulmonary disease (COPD) remains the third leading cause of death worldwide, and conventional bronchodilator‐based therapies have limited efficacy in preventing exacerbations and disease progression. The 2024–2026 period represents a historic inflection point: three mechanistically distinct agents received Food and Drug ...
Naoya Fujino, Hisatoshi Sugiura
wiley   +1 more source

Shaping Function: Polymeric 3D Systems With Unconventional Geometries for Biomedical Applications

Small, Volume 22, Issue 33, 12 June 2026.
Particle shape is a key design parameter governing biological interactions. Advances in fabrication enable precise control over anisotropy and compartmentalization, allowing modulation of cellular uptake, transport, and biodistribution, ultimately enhancing therapeutic performance. ABSTRACT Polymer geometry is a primary determinant of physical behavior
Francisca G. Perfeito, Mariana B. Oliveira, João F. Mano   +2 more
wiley   +1 more source

Collaboration as a Catalyst for Advancing Rare Disease Research: The Experience of the Rare Diseases Clinical Research Network

Clinical and Translational Science, Volume 19, Issue 6, June 2026.
ABSTRACT The Rare Diseases Clinical Research Network (RDCRN) was established to improve diagnosis, treatment, and research collaboration across rare diseases through collaborative, multi‐site, translational, and clinical research. Its governance framework promotes efficient data sharing and collaboration among research consortia, NIH representatives ...
Mirna Chehade, Sheridan Meyers, Talaya McCright‐Gill, Rogerwene Gifford, Mustafa Sahin, Michael E. Shy, Michele Manion, Dakota Campbell, Marc E. Rothenberg, Maurizio Macaluso   +9 more
wiley   +1 more source

Effects of 12 weeks of aerobic training on autonomic modulation, mucociliary clearance, and aerobic parameters in patients with COPD

International Journal of COPD, 2015
Marceli Rocha Leite,1 Ercy Mara Cipulo Ramos,1 Carlos Augusto Kalva-Filho,2 Ana Paula Coelho Figueira Freire,1 Bruna Spolador de Alencar Silva,1 Juliana Nicolino,1 Alessandra Choqueta de Toledo-Arruda,3 Marcelo Papoti,4 Luiz Carlos Marques Vanderlei,1 ...
Leite MR, Ramos EMC, Kalva-Filho CA, Freire APCF, Silva BSA, Nicolino J, Toledo-Arruda AC, Papoti M, Vanderlei LCM, Ramos D   +9 more
doaj  

Bridging Rare to Common Diseases: Precision Medicine and the Transforming Landscape of Pediatric Allergy and Immunology

Pediatric Allergy and Immunology, Volume 37, Issue 6, June 2026.
This graphical abstract illustrates the conceptual framework linking rare and common diseases in pediatric allergy and immunology through precision medicine. On the left, rare conditions such as inborn errors of immunity and primary atopic disorders represent well‐defined monogenic models that reveal fundamental mechanisms of immune dysregulation.
Riccardo Castagnoli, Martina Votto, Ivan Taietti, Maria Isabel Delgado‐Dolset, Rubén Fernández‐Santamaría, Martha Jimenez Freites, Mattia Giovannini, Mark Kačar, Aspasia Karavelia, Janice Layhadi, Urszula Radzikowska, Cezmi A. Akdis, Mubeccel Akdis, Marketa Bloomfield, Francesco Cinetto, Antoine Deschildre, Jonathan Hourihane, Susanne Lau, Antonio Nieto‐Garcia, Ismail Ogulur, Liam O'Mahony, Mohamed Shamji, Milena Sokolowska, Maria Jose Torres, Sophia Tsabouri, Philippe Eigenmann, on behalf of the EAACI‐Clemens von Pirquet Foundation   +26 more
wiley   +1 more source