Results 41 to 50 of about 31,045 (237)

The relevance of the application mukoactive preparations in patients with inflammatory pathology of ent organs

Медицинский совет, 2018
The mucous membrane of the respiratory tract is the first line of protection of the human body from various damaging agents. This function is provided by mucociliary clearance and its component by mucociliary transport.
V. M. Svistushkin, G. N. Nikiforova, D. M. Pshonkina, O. Yu. Karpovа   +3 more
doaj   +1 more source

Hypertonic Saline Therapy in Cystic Fibrosis: Do Population Shifts Caused by the Osmotic Sensitivity of Infecting Bacteria Explain the Effectiveness of this Treatment? [PDF]

, 2010
Cystic fibrosis (CF) is caused by a defect in the CF transmembrane regulator that leads to depletion and dehydration of the airway surface liquid (ASL) of the lung epithelium, providing an environment that can be infected by bacteria leading to increased
Ben eRyall, Huw D Williams, Jacob G Bundy, James E.A. Zlosnik, Volker eBehrends, Volker eBehrends   +5 more
core   +2 more sources

Environmental pollutants damage airway epithelial cell cilia: Implications for the prevention of obstructive lung diseases

Thoracic Cancer, 2020
Mucociliary epithelium lining the upper and lower respiratory tract constitutes the first line of defense of the airway and lungs against inhaled pollutants and pathogens.
Yu Cao, Miao Chen, Dan Dong, Songbo Xie, Min Liu   +4 more
doaj   +1 more source

In Vitro Ciliotoxicity and Cytotoxicity Testing of Repeated Chronic Exposure to Topical Nasal Formulations for Safety Studies

Pharmaceutics, 2021
Certain active drugs and excipients of nasal formulations may impair ciliary function and mucociliary clearance. The ciliary beat frequency (CBF) is a key parameter for determining mucociliary clearance rate, and in vitro assessments of CBF have proven ...
Larisa Tratnjek, Nadica Sibinovska, Katja Kristan, Mateja Erdani Kreft   +3 more
doaj   +1 more source

The effects of smoking and smoking cessation on nasal mucociliary clearance, mucus properties and inflammation

Clinics
OBJECTIVE: The aim of the present study was to assess nasal mucociliary clearance, mucus properties and inflammation in smokers and subjects enrolled in a Smoking Cessation Program (referred to as quitters). METHOD: A total of 33 subjects with a median (
Daniela Mitiyo Odagiri Utiyama, Carolina Tieko Yoshida, Danielle Miyuki Goto, Tômas de Santana Carvalho, Ubiratan de Paula Santos, Andreas Rembert Koczulla, Paulo Hilário Nascimento Saldiva, Naomi Kondo Nakagawa   +7 more
doaj   +1 more source

Effect of airway clearance therapies on mucociliary clearance in adults with cystic fibrosis: A randomized controlled trial.

PLoS ONE, 2022
BackgroundCystic fibrosis (CF) is an inherited disorder causing impaired mucociliary clearance within the respiratory tract, and is associated with bronchiectasis, chronic respiratory infections, and early death. Airway clearance therapies have long been
Aaron Trimble, Kirby Zeman, Jihong Wu, Agathe Ceppe, William Bennett, Scott Donaldson   +5 more
doaj   +1 more source

Airway Clearance Techniques for Primary Ciliary Dyskinesia; is the Cystic Fibrosis literature portable? [PDF]

, 2018
Primary Ciliary Dyskinesia (PCD) is a rare inherited disease with impaired mucociliary clearance. Airway clearance techniques (ACTs) are commonly recommended for patients with PCD to facilitate mucus clearance, despite a lack of evidence in this group ...
Barbato, Bush, Bush, Chevaillier, Cohen-Cymberknoh, Dell, Desai, El-Abiad, Ellerman, Farrell, Frownfelter, Gokdemir, Green, Gremmo, Irving, Jain, Kennedy, Kuehni, Lim, Lucas, Lucas, Lupton-Smith, McCarren, McManus, McShane, Miller, Narayan, Noone, Oxman, O’Callaghan, O’Donnell, Phillips, Prasad, Pryor, Sanderson, Schofield, Shah, Smyth, Strippoli, Valerio, van Der Schans, Werner, Whalley   +42 more
core   +1 more source

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

Naso-mucociliary Clearance Time among Patients with Chronic Rhinosinusitis in Ilorin, North-central Nigeria

Nigerian Postgraduate Medical Journal
Context: The mucociliary clearance system is an important component in the prevention of chronic inflammation of the nasal and paranasal sinus. Aim: The study aims to establish the normal values of mucociliary clearance in our region and to study the ...
Olushola Abdulrahman Afolabi, Segun Segun-Busari, Habeeb Kayodele Omokanye, Muritala Jimoh, Iheayi O. Iheagwu, Wasiu Omotosho, Saad O. Idris, Kenechukwu Uche-Okonkwo, Biodun Sulyman Alabi, Adekunle David Dunmade, Foluwasayo E. Ologe   +10 more
doaj   +1 more source

The Complex Interplay of Pulmonary Kinetic Processes [PDF]

, 2018
The inhalation route is frequently used to administer drugs for the management of respiratory diseases such as asthma or chronic obstructive pulmonary disease.
Borghardt, Jens Markus, Kloft, Charlotte, Sharma, Ashish   +2 more
core   +1 more source