Results 51 to 60 of about 434,754 (278)

Comparison by Objective Parameters in Patients with Chronic Rhinosinusitis Managed Medically and Surgically (with and without Powered Instruments)

Allergy & Rhinology, 2016
Objective To compare mucociliary clearance time and quality of life in patients who underwent sinus surgery using conventional and powered instruments, and in patients who were treated nonsurgically.
Samarendra Behera M.S., D.N.B., Satyawati Mohindra M.S., D.N.B., Sourabha K. Patro M.S., D.N.B., Ashok K. Gupta M.S., D.N.B.   +3 more
doaj   +1 more source

Evaluation of the nasal mucociliary transport rate by rhinoscintigraphy before and after surgery in patients with deviated nasal septum [PDF]

, 2009
In this study, we have investigated the effect of nasal septal deviation (NSD) on nasal mucociliary activity and how does a septoplasty operation affecs the nasal mucociliary transport rate in the first and third months during the post-operative period ...
Cahit Polat, Zeki Dostbil
core   +1 more source

The relevance of the application mukoactive preparations in patients with inflammatory pathology of ent organs

Медицинский совет, 2018
The mucous membrane of the respiratory tract is the first line of protection of the human body from various damaging agents. This function is provided by mucociliary clearance and its component by mucociliary transport.
V. M. Svistushkin, G. N. Nikiforova, D. M. Pshonkina, O. Yu. Karpovа   +3 more
doaj   +1 more source

Environmental pollutants damage airway epithelial cell cilia: Implications for the prevention of obstructive lung diseases

Thoracic Cancer, 2020
Mucociliary epithelium lining the upper and lower respiratory tract constitutes the first line of defense of the airway and lungs against inhaled pollutants and pathogens.
Yu Cao, Miao Chen, Dan Dong, Songbo Xie, Min Liu   +4 more
doaj   +1 more source

In Vitro Ciliotoxicity and Cytotoxicity Testing of Repeated Chronic Exposure to Topical Nasal Formulations for Safety Studies

Pharmaceutics, 2021
Certain active drugs and excipients of nasal formulations may impair ciliary function and mucociliary clearance. The ciliary beat frequency (CBF) is a key parameter for determining mucociliary clearance rate, and in vitro assessments of CBF have proven ...
Larisa Tratnjek, Nadica Sibinovska, Katja Kristan, Mateja Erdani Kreft   +3 more
doaj   +1 more source

Inhaled hypertonic saline for cystic fibrosis: reviewing the potential evidence for modulation of neutrophil signalling and function. [PDF]

, 2015
Cystic fibrosis (CF) is a multisystem disorder with significantly shortened life expectancy. The major cause of mortality and morbidity is lung disease with increasing pulmonary exacerbations and decline in lung function predicting significantly poorer ...
Dunlea, Danielle M, Lacey, Noreen, McCarthy, Cormac, Dr, McElvaney, Noel G, McElvaney, Oliver J, Pohl, Kerstin, Reeves, Emer P, Vijayan, Maya Sakthi N, White, Michelle M   +8 more
core   +1 more source

Multiscale mechanics of mucociliary clearance in the lung

Philosophical Transactions of the Royal Society of London. Biological Sciences, 2019
Mucociliary clearance (MCC) is one of the most important defence mechanisms of the human respiratory system. Its failure is implicated in many chronic and debilitating airway diseases.
J. Nawroth, A. M. van der Does, A. Ryan (Firth), E. Kanso   +3 more
semanticscholar   +1 more source

Effect of airway clearance therapies on mucociliary clearance in adults with cystic fibrosis: A randomized controlled trial.

PLoS ONE, 2022
BackgroundCystic fibrosis (CF) is an inherited disorder causing impaired mucociliary clearance within the respiratory tract, and is associated with bronchiectasis, chronic respiratory infections, and early death. Airway clearance therapies have long been
Aaron Trimble, Kirby Zeman, Jihong Wu, Agathe Ceppe, William Bennett, Scott Donaldson   +5 more
doaj   +1 more source

Hypertonic Saline Therapy in Cystic Fibrosis: Do Population Shifts Caused by the Osmotic Sensitivity of Infecting Bacteria Explain the Effectiveness of this Treatment? [PDF]

, 2010
Cystic fibrosis (CF) is caused by a defect in the CF transmembrane regulator that leads to depletion and dehydration of the airway surface liquid (ASL) of the lung epithelium, providing an environment that can be infected by bacteria leading to increased
Ben eRyall, Huw D Williams, Jacob G Bundy, James E.A. Zlosnik, Volker eBehrends, Volker eBehrends   +5 more
core   +2 more sources

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source