Results 31 to 40 of about 654,486 (255)

Mutations in TP73 cause impaired mucociliary clearance and lissencephaly.

American Journal of Human Genetics, 2021
TP73 belongs to the TP53 family of transcription factors and has therefore been well studied in cancer research. Studies in mice, however, have revealed non-oncogenic activities related to multiciliogenesis. Utilizing whole-exome sequencing analysis in a
J. Wallmeier, D. Bracht, H. Alsaif, G. Dougherty, H. Olbrich, S. Cindrić, M. Dzietko, C. Heyer, N. Teig, C. Thiels, E. Faqeih, Aqeela Alhashim, Sameena Khan, I. Mogarri, M. Almannai, Wadha Hilal Al Otaibi, F. Alkuraya, C. Koerner-Rettberg, H. Omran   +18 more
semanticscholar   +1 more source

Effect of lumacaftor-ivacaftor on mucociliary clearance and clinical outcomes in cystic fibrosis: Results from the PROSPECT MCC sub-study

Journal of Cystic Fibrosis, 2021
CFTR function is required for normal mucociliary clearance (MCC) and cough-assisted clearance (CC). Lumacaftor-ivacaftor is approved for use in people with cystic fibrosis (CF) carrying two copies of F508del-CFTR. In this observational study performed at
S. Donaldson, B. Laube, P. Mogayzel, T. Corcoran, J. Pilewski, Agathe S. Ceppe, Ji-Hong Wu, P. Bhambhvani, F. Ratjen, S. Sagel, J. P. Clancy, S. Rowe, W. Bennett   +12 more
semanticscholar   +1 more source

Hyaluronic Acid Effects on Impaired Mucociliary Clearance Due to Radiotherapy

B-ENT, 2022
Objective: This study aims to determine whether there is any effect of hyaluronic acid-containing nasal wash solutions in patients with impaired mucociliary clearance after radiotherapy. Methods: Patients who received radiotherapy to nasopharynx and neck
Tuncay Tunçcan, Burcu Vural, Fatih Göksel, Caner Kılıç, Samet Özlügedik, Arzubetül Duran, Ayça Ant   +6 more
doaj   +2 more sources

Air Pollution and Nasal Mucociliary Clearance Time among Urban and Rural Residents in Two Philippine Communities

Philippine Journal of Otolaryngology Head and Neck Surgery, 2020
Objective: To measure the nasal mucociliary clearance (NMC) time among adults residing in two Philippine communities with different air quality indices using the saccharin and methylene blue test.
Soraya Joson, Joman Laxamana
doaj   +1 more source

Objective Assessment of The Nasal Mucociliary Clearance after Submucosal Diode Laser Turbinoplasty [PDF]

Zagazig University Medical Journal
Background: Mucociliary clearance is an important parameter for assessment of the procedure used for the surgical treatment of hypertrophied inferior turbinate.
Mohammad Abdelbary, Heba Mahmoud Hamdy, Mohammed Abdelhady   +2 more
doaj   +1 more source

Effect of adjunctive sodium hyaluronate versus surfactant nasal irrigation on mucociliary clearance in allergic rhinitis: a single-blind, randomised, controlled study

Journal of Laryngology and Otology, 2021
Objective To investigate the effects of nasal irrigation with sodium hyaluronate and surfactant solutions on mucociliary clearance time in patients with mild persistent allergic rhinitis.
E. Ocak, S. Mulazimoglu, D. Kocaoz, E. Mirici, E. Dagli, A. Acar   +5 more
semanticscholar   +1 more source

Author Correction: A human ciliopathy reveals essential functions for NEK10 in airway mucociliary clearance [PDF]

, 2020
Correction to "A human ciliopathy reveals essential functions for NEK10 in airway mucociliary ...
Montoro, Daniel T., Frenkel, Evgeni M., Omran, Heymut, Hariri, Lida P., Yang, Jason, Taylor, Martin S., Tearney, Guillermo J., Alkuraya, Fowzan S., Shamseldin, Hanan E., Black, Katharine E., Almogarri, Ibrahim, Vinarsky, Vladimir, Daniels, M. Leigh Anne, Sabatini, David M., Zariwala, Maimoona A., Leung, Hui Min, Dougherty, Gerard W., Chivukula, Raghu R., Sears, Patrick R., Carson, Johnny, Knowles, Michael R.   +20 more
core   +1 more source

Breathing on chip: Dynamic flow and stretch accelerate mucociliary maturation of airway epithelium in vitro

Materials Today Bio, 2023
Human lung function is intricately linked to blood flow and breathing cycles, but it remains unknown how these dynamic cues shape human airway epithelial biology.
Janna C. Nawroth, Doris Roth, Annemarie van Schadewijk, Abilash Ravi, Tengku Ibrahim Maulana, Christiana N. Senger, Sander van Riet, Dennis K. Ninaber, Amy M. de Waal, Dorothea Kraft, Pieter S. Hiemstra, Amy L. Ryan, Anne M. van der Does   +12 more
doaj   +1 more source

Mucociliary clearance in chronic sinusitis [PDF]

Indian Journal of Otolaryngology and Head & Neck Surgery, 1998
Mucociliary clearance is an important defence mechanism of upper and lower respiratory tracts. Any disturbance in the mechanism leads to stagnation of secretions and secondary infection with prolonged mucociliary clearance time. The present study was undertaken to establish normal mucociliary clearance time in our region and to evaluate its diagnostic ...
S M, Birdi, S, Singh, A, Singh
openaire   +2 more sources

Rotation frequency of human bronchial and nasal epithelial spheroids as an indicator of mucociliary function [PDF]

, 2006
Background: We evaluated a new in vitro model for mucociliary transport function. Spheroids of human respiratory epithelium show beating cilia at their surface.
Bergner, Albrecht, Gamarra, Fernando, Stocker, Ingrid, Grundler, Stefan, Stauss, Elisabeth, Huber, Rudolf M.   +5 more
core   +1 more source