A human ciliopathy reveals essential functions for NEK10 in airway mucociliary clearance
Nature Medicine, 2020 Mucociliary clearance, the physiological process by which mammalian conducting airways expel pathogens and unwanted surface materials from the respiratory tract, depends on the coordinated function of multiple specialized cell types, including basal stem
R. Chivukula +20 more
semanticscholar +1 more source
Physiopathological rationale of using high-flow nasal therapy in the acute and chronic setting: A narrative review [PDF]
, 2019 Chronic lung disease and admissions due to acute respiratory failure (ARF) are becoming increasingly common. Consequently, there is a growing focus on optimizing respiratory support, particularly non-invasive respiratory support, to manage these ...
Cortegiani A. +2 more
core +1 more source
Turkish Archives of Otorhinolaryngology, 2013 Objective:To compare the postoperative mucociliary clearance time in septoplasty with and without nasal packing.Methods:Forty-six patients with nasal septal deviation (20 women, 26 men) were assessed in this study.
İbrahim Çukurova +5 more
doaj +1 more source
Clinics, 2011 OBJECTIVE: To study the effects of mycophenolate sodium on mucociliary clearance. INTRODUCTION: Mycophenolate is one of the most commonly used immunosuppressive drugs in lung transplantation.
Viviane Ferreira Paes e Silva +6 more
doaj +1 more source
Nasal Mucociliary Clearance in Smokers: A Systematic Review
International Archives of Otorhinolaryngology, 2020 Introduction Smoking is one of the most important causes of mortality and morbidity in the world, as it is related to the risk factor and etiology of respiratory-tract diseases.
Awal Prasetyo +2 more
semanticscholar +1 more source
Mucociliary clearance, airway inflammation and nasal symptoms in urban motorcyclists
Clinics, 2014 OBJECTIVES: There is evidence that outdoor workers exposed to high levels of air pollution exhibit airway inflammation and increased airway symptoms.
Tereza C.S. Brant +11 more
doaj +1 more source
Combination inhaled steroid and long-acting beta2-agonist versus tiotropium for chronic obstructive pulmonary disease [PDF]
, 2010 Background Combination therapy (inhaled corticosteroids and long-acting beta(2)-agonists) and tiotropium are both used in the treatment of chronic obstructive pulmonary disease (COPD).
Appleton +20 more
core +1 more source
The Efficacy of Therapeutic Respiratory Muscle Training Interventions in People with Bronchiectasis: A Systematic Review and Meta-Analysis [PDF]
, 2020 Background: Respiratory muscle dysfunction is an important health problem with high morbidity and mortality and associated costs in patients with bronchiectasis (BC).
Casuso-Holgado, Maria Jesus +5 more
core +3 more sources
Influenza A virus enhances ciliary activity and mucociliary clearance via TLR3 in airway epithelium
Respiratory Research, 2020 Background Viral respiratory tract infections, such as influenza A virus (IAV), are common and life-threatening illnesses worldwide. The mechanisms by which viruses are removed from the respiratory tract are indispensable for airway host defense ...
Y. Kamiya +15 more
semanticscholar +1 more source
Smoking is associated with shortened airway cilia. [PDF]
PLoS ONE, 2009 BACKGROUND:Whereas cilia damage and reduced cilia beat frequency have been implicated as causative of reduced mucociliary clearance in smokers, theoretically mucociliary clearance could also be affected by cilia length.
Philip L Leopold +5 more
doaj +1 more source