Results 31 to 40 of about 21,273 (241)

In Vitro Ciliotoxicity and Cytotoxicity Testing of Repeated Chronic Exposure to Topical Nasal Formulations for Safety Studies

Pharmaceutics, 2021
Certain active drugs and excipients of nasal formulations may impair ciliary function and mucociliary clearance. The ciliary beat frequency (CBF) is a key parameter for determining mucociliary clearance rate, and in vitro assessments of CBF have proven ...
Larisa Tratnjek, Nadica Sibinovska, Katja Kristan, Mateja Erdani Kreft   +3 more
doaj   +1 more source

Does menopause effect nasal mucociliary clearance time?

, 2015
SIMSEK, GOKCE/0000-0001-5281-0986The aim of this study was to investigate the effect of menopause on nasal mucociliary clearance time by comparing the results of premenopausal and postmenopausal women.
Akkoca, Ayse Neslin, Akbay, Ercan, Ozler, Gul Soylu, Karapinar, Oya Soylu, Simsek, Gokce Ozel   +4 more
core   +1 more source

A comparison of nasal mucociliary clearance time in Covid-19 and variant Covid-19 patients

, 2023
WOS:000962413400003Objective: The aim of this study was to compare nasal mucociliary clearance times in coronavirus disease 2019 and variant coronavirus disease 2019 patients and a control group.
Serif Samil Kahraman, Kahraman, Şerif Şamil, Fatih Yucedag, Yücedağ, Fatih   +3 more
core   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

Effect of airway clearance therapies on mucociliary clearance in adults with cystic fibrosis: A randomized controlled trial.

PLoS ONE, 2022
BackgroundCystic fibrosis (CF) is an inherited disorder causing impaired mucociliary clearance within the respiratory tract, and is associated with bronchiectasis, chronic respiratory infections, and early death. Airway clearance therapies have long been
Aaron Trimble, Kirby Zeman, Jihong Wu, Agathe Ceppe, William Bennett, Scott Donaldson   +5 more
doaj   +1 more source

Effects of Aging on Nasal Mucociliary Clearance

, 2011
Nasal mucociliary clearance is a primary physiological defense mechanism of upper as well as lower respiratory tract, and thus maintains the state of health of the respiratory tract.
Rupender K Ranga, Jyoti Yadav, Jagat Singh   +2 more
core   +1 more source

The effect of chemotherapy on olfactory function and mucociliary clearance

, 2021
Objectives Olfactory sensory neurons and the olfactory mucosa are both important for optimal olfactory function. The potential nasal mucosal toxicity of chemotherapy regimens has not been assessed yet. The aim of this study was to objectively investigate
Colak, Mustafa, Eravci, Fakih Cihat, Acikgoz, Yusuf, Ergun, Yakup, Ozcan, Kursat Murat, Ucar, Gokhan, Ikinciogullari, Aykut   +6 more
core   +1 more source

Naso-mucociliary Clearance Time among Patients with Chronic Rhinosinusitis in Ilorin, North-central Nigeria

Nigerian Postgraduate Medical Journal
Context: The mucociliary clearance system is an important component in the prevention of chronic inflammation of the nasal and paranasal sinus. Aim: The study aims to establish the normal values of mucociliary clearance in our region and to study the ...
Olushola Abdulrahman Afolabi, Segun Segun-Busari, Habeeb Kayodele Omokanye, Muritala Jimoh, Iheayi O. Iheagwu, Wasiu Omotosho, Saad O. Idris, Kenechukwu Uche-Okonkwo, Biodun Sulyman Alabi, Adekunle David Dunmade, Foluwasayo E. Ologe   +10 more
doaj   +1 more source

A Non‐Canonical Role of SMAD4 in Regulating 3D Genome Architecture to Inhibit Lung Squamous Cell Carcinoma Development

Advanced Science, EarlyView.
SMAD4 is identified as a guardian of 3D genome architecture in lung squamous cell carcinoma. Loss of SMAD4 unleashes EP300 at chromatin loop anchors, strengthening enhancer–promoter looping and H3K27ac at the SOX2 locus to drive aberrant SOX2 activation and tumor cell proliferation.
Qian Tang, Chen Lian, Xinyan Han, Xuhan Zhang, Zihan Wang, Boyu Wang, Taoyu Zhu, Xinrui Lin, Xiaolei Wang, Yaping Xu, Manyu Xiao, Zijin Wang, Junming Li, Silin Chen, Yunze Wang, Yufei Liu, Songsong Li, Zuolin Shen, Xi Lu, Xueqi Han, Yilu Zhou, Mingyang Xiao, Jiayi Ran, Xiaoran Cao, Xinyi Xu, Hugo Sámano‐Sánchez, Alfredo Rodríguez, Lian Wang, Shuifang Chen, Zhanyu Xu, Shirong Zhang, Nuo Yang, Yong Tang, Jian Liu   +33 more
wiley   +1 more source

Nasal Mucociliary Clearance in Allergic Rhinitis in Children

, 2010
Allergic rhinitis in children is not an uncommon disease in India. Our objective was to evaluate the effect of allergic rhinitis on nasal mucociliary clearance.
Rupender K Ranga, Jyoti Yadav, Jagat Singh   +2 more
core   +1 more source