Results 21 to 30 of about 654,486 (255)
Mucociliary clearance: pathophysiological aspects
Clinical Physiology and Functional Imaging, 2013 SummaryMucociliary clearance has long been known to be a significant innate defence mechanism against inhaled microbes and irritants. Important knowledge has been gathered regarding the anatomy and physiology of this system, and in recent years, extensive studies of the pathophysiology related to lung diseases characterized by defective mucus clearance
Munkholm, Mathias, Mortensen, Jann
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Volatile anesthetics and mucociliary clearance.
Minerva anestesiologica, 2008 The aim of this prospective, randomized, double blind study was to evaluate the possible modification of in vivo nasal mucociliary clearance by three different volatile agents: sevoflurane, isoflurane and desflurane, following intravenous induction and tracheal intubation.Following institutional approval and informed consent, 60 patients scheduled for ...
Kutluhan, AHMET +5 more
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Mucociliary clearance in bronchiectasis
The mucociliary clearance system is the first defence of the respiratory tract against inhalation of foreign material. Most patients with bronchiectasis have mucociliary dysfunction.
Lidia Perea, Amelia Shoemark
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Nature Communications, 2021 Understanding how SARS-CoV-2 spreads within the respiratory tract is important to define the parameters controlling the severity of COVID-19. Here we examine the functional and structural consequences of SARS-CoV-2 infection in a reconstructed human ...
R. Robinot +24 more
semanticscholar +1 more source
Respiratory Medicine, 2023 Bronchial asthma is a heterogeneous respiratory condition characterized by chronic airway inflammation, airway hyperresponsiveness and airway structural changes (known as remodeling).
M. Jeseňák +8 more
semanticscholar +1 more source
On the role of viscoelasticity in mucociliary clearance: a hydrodynamic continuum approach
Journal of Fluid Mechanics, 2023 We present numerical and analytical predictions of mucociliary clearance based on the continuum description of a viscoelastic mucus film, where momentum transfer from the beating cilia is represented via a Navier-slip boundary condition introduced by ...
A. Choudhury +4 more
semanticscholar +1 more source
Modelling mucociliary clearance [PDF]
Respiratory Physiology & Neurobiology, 2008 Mathematical modelling of the fluid mechanics of mucociliary clearance (MCC) is reviewed and future challenges for researchers are discussed. The morphology of the bronchial and tracheal airway surface liquid (ASL) and ciliated epithelium are briefly introduced. The cilia beat cycle, beat frequency and metachronal coordination are described, along with
Smith, D, Gaffney, E, Blake, JR
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Regional Differences in Mucociliary Clearance in the Upper and Lower Airways
Frontiers in Physiology, 2022 As the nasal cavity is the portal of entry for inspired air in mammals, this region is exposed to the highest concentration of inhaled particulate matter and pathogens, which must be removed to keep the lower airways sterile.
T. D. Rogers +7 more
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Impact of smoking on nasal mucociliary clearance time in Kano metropolis, Nigeria
World Journal of Otorhinolaryngology-Head and Neck Surgery, 2023 Background Mucociliary clearance is an important defense mechanism in human upper and lower respiratory airways. Impairment of this process by certain conditions such as cigarette smoking can predispose to chronic infection and neoplasm of the nose and ...
Ahmad Mahmud +7 more
doaj +1 more source
Prediction of nasal spray drug absorption influenced by mucociliary clearance
PLoS ONE, 2021 Evaluation of nasal spray drug absorption has been challenging because deposited particles are consistently transported away by mucociliary clearance during diffusing through the mucus layer.
Yi-Dan Shang +5 more
semanticscholar +1 more source