Results 41 to 50 of about 18,615 (195)

Evaluation of Nasal Mucociliary Activity in Patients With Psoriasis Vulgaris

Dermatology Practical & Conceptual
Introduction: Psoriasis, a chronic inflammatory dermatological condition, is marked by recurring periods of activity and quiescence. This persistent inflammation contributes to a range of associated health issues.
Mehmet Akif Dundar, Selami Aykut Temiz, Ismail Hakkı Tuncez, Elif Emre, Sadettin Emre, Recep Dursun   +5 more
doaj   +1 more source

Regulation of mucociliary clearance in health and disease [PDF]

European Respiratory Journal, 1999
Airway secretions are cleared by mucociliary clearance (MCC), in addition to other mechanisms such as cough, peristalsis, two-phase gas-liquid flow and alveolar clearance. MCC comprises the cephalad movement of mucus caused by the cilia lining the conducting airways until it can be swallowed or expectorated.
E, Houtmeyers, R, Gosselink, G, Gayan-Ramirez, M, Decramer   +3 more
openaire   +2 more sources

Overcoming intranasal delivery barriers with ultrastable polyzwitterionic siRNA nanocages for enhanced glioblastoma therapy

BMEMat, EarlyView.
A ROS‐responsive, zwitterionic nanocage enables stable, intranasal siRNA delivery to glioblastoma, promoting deep tumor penetration via non‐degradative pathways and trigeminal nerve transport. This platform achieves durable gene silencing and tumor suppression, offering a non‐invasive, storage‐stable strategy for treating glioma and other neurological ...
Jingwen Xie, Jingxing Si, Xiaobei Deng, Jing Tan, Ruijie Zhu, Jizhou Qi, Gaoxia Ma, Bin Wang, Yi Wang, Yunzhou Guo, Yuping Chen, Shiqun Shao, Youqing Shen   +12 more
wiley   +1 more source

Compliant hydrogel cuff coating with real‐time pressure monitoring and antibiofilm capabilities for ventilator‐associated pneumonia prophylaxis

BMEMat, EarlyView.
A soft‐compliant hydrogel cuff coating combines real‐time pressure monitoring with intrinsic antibacterial activity for prophylaxis of ventilator‐associated pneumonia. A flexible pressure‐sensing patch is embedded in the coating to enable wireless dynamic monitoring of endotracheal cuff pressure through Bluetooth.
Jin Chai, Yifu Tan, Jiaheng Liang, Shen Liu, Jiabin Zhao, Shanbo Ma, Chunxin Liu, Minghua Du, Mark Selvan, Xiaopeng Shi, Liqiang Song, Peng Li   +11 more
wiley   +1 more source

Dobutamine, Epinephrine, and Milrinone Accelerate Particle Transport Velocity in Murine Tracheal Epithelium via Ca²⁺ Release from Caffeine-Sensitive Internal Stores

Cells
Mucociliary clearance, the ability of the respiratory tract to protect the integrity of the airways through the mechanical removal of potentially harmful substances, is of enormous importance during intensive care treatment.
Götz Schmidt, Frederic Borchers, Sabrina Müller, Amir Ali Akbari, Fabian Edinger, Michael Sander, Christian Koch, Michael Henrich   +7 more
doaj   +1 more source

The Effects of the Anti-aging Protein Klotho on Mucociliary Clearance

Frontiers in Medicine, 2020
α-klotho (KL) is an anti-aging protein and has been shown to exert anti-inflammatory and anti-oxidative effects in the lung and pulmonary diseases such as chronic obstructive pulmonary disease (COPD) and cystic fibrosis.
Jaleesa Garth, Molly Easter, Elex Skylar Harris, Elex Skylar Harris, Juliette Sailland, Lisa Kuenzi, Samuel Chung, Samuel Chung, John S. Dennis, John S. Dennis, Nathalie Baumlin, Nathalie Baumlin, Adegboyega T. Adewale, Steven M. Rowe, Steven M. Rowe, Gwendalyn King, Christian Faul, Jarrod W. Barnes, Jarrod W. Barnes, Matthias Salathe, Matthias Salathe, Stefanie Krick, Stefanie Krick   +22 more
doaj   +1 more source

Nanoplastics: Methods, Exposure and Effects on Domestic, Farm and Wild Animals

Journal of Applied Toxicology, EarlyView.
ABSTRACT Nanoplastics (NPs) are synthetic polymer particles ranging in size from 1 nm to 1 μm that have been identified as a major concern for ecosystems and organisms due to their plethora of negative effects. The aim of this review is to provide a comprehensive overview of the knowledge relating to exposure and effects of NPs in domestic (i.e., farm ...
B. De Felice, M. Bertazzo, A. F. Tabaran, M. Parolini, R. P. Popa, A. Pintea, L. J. Spicer, A‐L. Nagy, F. Caloni   +8 more
wiley   +1 more source

Air Pollution Quinones Impair Intestinal Barrier Integrity and Endoplasmic Reticulum in Differentiated Caco‐2 Cells

Journal of Applied Toxicology, EarlyView.
ABSTRACT Particulate matter (PM) is a major global health threat, linked to millions of deaths annually. Beyond inhalation, PM components reach the gastrointestinal tract through the mucociliary escalator or contaminated food and water. Among PM's organic fraction, redox‐active quinones such as 1,2‐naphthoquinone (NQ) and 9,10‐phenanthrenequinone (PQ ...
Franco Cervellati, Giulia Trinchera, Alice Casoni, Alessandra Pecorelli, Mascia Benedusi, Maria Chiara Pietrogrande, Giuseppe Valacchi   +6 more
wiley   +1 more source

Effect of needle puncture and electro-acupuncture on mucociliary clearance in anesthetized quails

BMC Complementary and Alternative Medicine, 2006
Background Acupuncture therapy for obstructive respiratory diseases has been effectively used in clinical practice and the acupuncture points or acupoints of Zhongfu and Tiantu are commonly-used acupoints to treat patients with the diseases.
Wang Tianshan, Xutian Stevenson, Sun Feng, Wang Jiulin, Tai Shusheng, King Malcolm   +5 more
doaj   +1 more source

Otovent Versus Valsalva: Physiological Insights for Diagnostic and Therapeutic Autoinflation in Eustachian Tube Dysfunction

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objectives Autoinflation aids assessment of Eustachian tube function, or as a conservative treatment for obstructive Eustachian tube dysfunction. This study compares the physiological characteristics of 2 autoinflation techniques, the Otovent® device and the Valsalva manoeuvre, to inform clinical application for both diagnosis and therapy ...
Kiran Joshi, Victor Lim, Victor Ho, James Tysome, Matthew Smith   +4 more
wiley   +1 more source