Results 71 to 80 of about 31,045 (237)

Primary Ciliary Dyskinesia: An Update on Clinical Aspects, Genetics, Diagnosis, and Future Treatment Strategies [PDF]

, 2017
Primary ciliary dyskinesia (PCD) is an orphan disease (MIM 244400), autosomal recessive inherited, characterized by motile ciliary dysfunction. The estimated prevalence of PCD is 1:10,000 to 1:20,000 live-born children, but true prevalence could be even ...
Abete, Afzelius, Afzelius, Afzelius, Alanin, Altenburg, Bartoloni, Behan, Bhatt, Bilton, Boaretto, Boe, Boon, Boon, Boon, Bradley, Brenner, Brown, Bush, Bush, Campbell, Carotenuto, Chang, Chang, Chernick, Cohen-Cymberknoh, Cole, Coren, Davis, Daviskas, De Benedetti, Desai, Deuse, Eastham, El-Abiad, Eliasson, Elkins, Ellerman, Fedakar, Ferkol, Ferkol, Fliegauf, Fliegauf, Flume, Fokkens, Fretzayas, Frommer, Fuchs, Gokdemir, Goutaki, Halbert, Hart, Hellinckx, Hill, Horani, Horani, Irving, Jeanson, Kartagener, Kellett, Kennedy, Kennedy, Kennedy, Kim, King, Knowles, Knowles, Knowles, Kobbernagel, Konstan, Kott, Kuehni, Kumar, Lai, Lebl, Leigh, Lucas, Lucas, Lucas, Lucas, Macchiarini, Mackerness, Madsen, Maglione, Maglione, Manna, Marks, Marthin, Marthin, Marthin, Mateos-Corral, McManus, Merveille, Mirra, Mitchison, Montella, Montella, Montella, Montella, Moore, Mossberg, Mullowney, Munro, Nakhleh, Nicolson, Noone, Noone, Oktem, Olbrich, Omran, Onoufriadis, Onoufriadis, O’Callaghan, O’Callaghan, Paff, Paff, Papon, Pasteur, Patella, Phillips, Picot, Pifferi, Potter, Prulière-Escabasse, Raidt, Rogers, Rutland, Sagel, Santamaria, Santamaria, Schwabe, Serisier, Shah, Shapiro, Shoemark, Sommer, Spagnolo, Stenbit, Stillwell, Sturgess, Svobodova, ten Berge, Valerio, Walker, Wallmeier, Werner, Werner, Wirschell, Wong, Yan-Wei, Zimmerman   +150 more
core   +1 more source

Uncovering Cystic Fibrosis Carrier: Insights From a Heterozygous CFTR‐F508del Rabbit Model

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) is a heterogeneous inflammatory disorder frequently associated with impaired mucociliary clearance and bacterial infection. Individuals carrying a single cystic fibrosis transmembrane conductance regulator (CFTR) mutation exhibit partial CFTR dysfunction and are increasingly recognized as being at risk ...
Do‐Yeon Cho, Alexis E. McFeely, Daniel Skinner, Shaoyan Zhang, Justin Hedvat, Weslee Ping‐ay, Daniel M. Beswick, Justin H. Turner, Bradford A. Woodworth, Jie Xu   +9 more
wiley   +1 more source

Cilia beating misalignment, immotility or death pathologically affect the efficiency of mucus-clearance

Communications Physics
To perform mucociliary clearance, motile cilia covering the surface of the respiratory tract coordinate their beating motions to push mucus out of the upper airways.
Émeline Laborie, Simone Melchionna, Fabio Sterpone   +2 more
doaj   +1 more source

Batuk Kronik pada Anak: masalah dan tata laksana

Sari Pediatri, 2016
Batuk kronik pada anak cukup banyak dijumpai dalam praktek sehari-hari. Pada pasien anak, gejala batuk yang kronik atau berulang dapat mengganggu aktivitas sehari-hari, mengurangi nafsu makan, dan pada akhirnya dapat mengganggu proses tumbuh kembang ...
Darmawan B Setyanto
doaj   +1 more source

Biofilm Exoproteins From Staphylococcus Species Impede Re‐Epithelialization of Nasal Epithelial Cells During Wound Healing and Cease Ciliary Beat Frequency

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Introduction Chronic rhinosinusitis (CRS) is an inflammatory disease with many different contributing factors, including bacterial infection. CRS patients are typically managed with medical therapies; however, these treatments frequently fail, leaving surgery as the only viable option.
Sintayehu Ambachew, Mahnaz Ramezanpour, Clare M. Cooksley, Emma F. Barry, Lindsay Durr, Kevin Aaron Fenix, P. J. Wormald, Alkis J. Psaltis, Sarah Vreugde   +8 more
wiley   +1 more source

Nasal Muco-ciliary transport time alteration: efficacy of 18 B Glycyrrhetinic acid

Multidisciplinary Respiratory Medicine, 2017
Background Mucociliary clearance is the main self-clearing system of the nasal cavity and paranasal sinuses. This is a very important means of non specific defence against continuous organic and inorganic contamination conveyed by air.
Desiderio Passali, Chiara Cappello, Giulio Cesare Passali, Cemal Cingi, Codrut Sarafoleanu, Luisa Maria Bellussi   +5 more
doaj   +1 more source

Airway cilia recovery post lung transplantation

Immunity, Inflammation and Disease, 2021
Background Normally functioning airway cilia is essential for efficient mucociliary clearance to protect the airway from various insults. Impaired clearance may lead to increased risk of infections and progressive lung damage.
Randy Suryadinata, Kovi Levin, Lynda Holsworth, Miranda Paraskeva, Philip Robinson   +4 more
doaj   +1 more source

Optimisation of growth conditions for ovine airway epithelial cell differentiation at an air-liquid interface [PDF]

, 2018
Respiratory tract infections are of significant concern in the agriculture industry. There is a requirement for the development of well-characterised in vitro epithelial cell culture models in order to dissect the diverse molecular interactions occurring
Berry, Catherine C., Davies, Robert L., O'Boyle, Nicky, Sutherland, Erin   +3 more
core   +2 more sources

Overcoming intranasal delivery barriers with ultrastable polyzwitterionic siRNA nanocages for enhanced glioblastoma therapy

BMEMat, EarlyView.
A ROS‐responsive, zwitterionic nanocage enables stable, intranasal siRNA delivery to glioblastoma, promoting deep tumor penetration via non‐degradative pathways and trigeminal nerve transport. This platform achieves durable gene silencing and tumor suppression, offering a non‐invasive, storage‐stable strategy for treating glioma and other neurological ...
Jingwen Xie, Jingxing Si, Xiaobei Deng, Jing Tan, Ruijie Zhu, Jizhou Qi, Gaoxia Ma, Bin Wang, Yi Wang, Yunzhou Guo, Yuping Chen, Shiqun Shao, Youqing Shen   +12 more
wiley   +1 more source

Toxicity of lunar dust

, 2012
The formation, composition and physical properties of lunar dust are incompletely characterised with regard to human health. While the physical and chemical determinants of dust toxicity for materials such as asbestos, quartz, volcanic ashes and urban ...
Alving, Asano, Basu, Bice Fubini, Bosquillon, Brain, Brown, Brunetto, Butler, Cain, Cain, Castranova, Castranova, Christoffersen, Dag Linnarsson, Damm, Darquenne, Darquenne, Darquenne, Darquenne, Darquenne, David J. Loftus, Dockery, Driscoll, Erin M. Tranfield, Ewing, Fanizza, Fenoglio, Fenoglio, Fenoglio, Fenoglio, Frampton, Fubini, Fubini, Fubini, Fubini, Fubini, Fubini, Fubini, Fubini, Fujishima, G. Kim Prisk, Gaier, Geiser, Gerde, Gerde, Ghiazza, Gustafsson, Hardy, Hardy, Harmsen, Heinrich, Hemmingsson, Heyder, Hill, Hong, Horanyi, Horwell, Horwell, Hurowitz, Ialenti, Ignarro, James, James, James Carpenter, Jones, Kamp, Kane, Karlsson, Khan-Mayberry, Kharitonov, Kharitonov, Kobrick, Lam, Lane, Lars L. Karlsson, Larsen, Latch, Lison, Lison, Liu, Liu, Loftus, Lucey, Lundberg, Lynch, MacLoughlin, McClellan, McKay, McKay, Moller, Mossman, Nel, Nel, Nemmar, Nikula, Norde, Oberdörster, Oberdörster, Oberdörster, Oberdörster, Park, Parsegian, Patil, Pauluhn, Pauluhn, Pawloski, Per Gerde, Persson, Peters, Peters, Peters, Peterson, Pezerat, Pope, Pope, Popov, Porter, Rask, Ricciardolo, Saffiotti, Sahai, Sakagami, Sakagami, Samet, Sanchez, Santana, Scheuch, Schwartz, Seagrave, Seaton, Seaton, Selg, Semmler, Shukla, Smaldone, Stahlhofen, Stanton, Sundblad, Taylor, Taylor, Taylor, Taylor, Thompson, Tranfield, Tronde, Tsuda, Turci, Turci, Urs Staufer, Vallyathan, van Eeden, von Klot, Wallace, Warheit, Warheit, West, Wim van Westrenen, Wong, Zanobetti   +159 more
core   +1 more source