Results 61 to 70 of about 2,851 (178)
Mucolytic and Antitussive Effects of Erdosteine
Journal of Pharmacy and Pharmacology, 1999 AbstractTo investigate the influence of erdosteine, a new homocysteine-derived expectorant, on airway clearance we studied the effects of the drug on the viscosity of mucin, on the mucociliary transport rate in quails, on airway secretion in rats and on the cough reflex in guinea-pigs.The active metabolite of erdosteine, M1 (10 μM to 1 mM ...
H, Hosoe +6 more
openaire +2 more sources
European Journal of Pain, Volume 30, Issue 6, July 2026.ABSTRACT Background Nonsteroidal anti‐inflammatory drugs (NSAIDs) provide effective analgesia but may paradoxically delay tissue recovery, pain resolution and contribute to chronic pain. Erdosteine, a thiol‐based prodrug with antioxidant and anti‐inflammatory properties, is a mucolytic used for treatment of respiratory diseases but has recently been ...
Lucas Vasconcelos Lima +7 more
wiley +1 more source
MUCOLYTICS FOR CHILDREN: DIFFICULT ISSUES, KEY SOLUTIONS
Вопросы современной педиатрии, 2014 The author analyzed the most common questions of mucolytic agents selection asked by clinicians. The various clinical effects of N-acetyl cysteine and indications for different forms of this drug, especially in infants, are discussed in the article ...
O. I. Simonova
doaj +1 more source
Health Science Reports, Volume 9, Issue 7, July 2026.ABSTRACT Background and Aims Dyspnea, a prevalent symptom among victims of chemical warfare exposed to sulfur mustard, presents substantial physiological and pharmacological challenges. Inhaling sulfur mustard in warfare may result in significant respiratory distress, emphasizing the necessity of investigating the underlying processes and treatment ...
Mahboobeh Ghasemzadeh Rahbardar +2 more
wiley +1 more source
Place of mucolytics in the treatment of acute sinusitis
Медицинский совет, 2019 Aim of the study - the analysis of the current understanding of local changes in the mucous membrane of PNS in AS, as well as methods of pharmacotherapy of the disease.
A. I. Kryukov +5 more
doaj +1 more source
Long-Term Productive Cough Caused by Tracheal Bronchus
Archives of Clinical and Experimental Surgery, 2012 We presented a 27-year-old man with a long-term productive cough and intermittent pneumonia without a remarkable medical history. Bronchoscopy revealed one tracheal bronchus with a narrow orifice.
Chih-Hao Chen +3 more
doaj +1 more source
Rational Mucolytic Therapy in the Complex Treatment of Bronchopulmonary Diseases in Children
Zdorovʹe Rebenka, 2012 The mechanisms of mucus production disorders in the respiratory tract in children are considered. The optimal therapeutic intervention techniques in violation of mucus transport and improvement of respiratory drainage are defined.
Ye.I. Yulish, A.A. Levchenko
doaj +1 more source
Zdorovʹe Rebenka, 2015 Violations of mucociliary clearance accompany any damage of the respiratory system. The paper presents the pathogenetic mechanisms of changes developing at this time and their consequences.
O.Ye. Chernyshova
doaj +1 more source
Critical Care Research and Practice, 2015 Aim. The extent to which mucolytics are utilised in mechanically ventilated asthmatic children is unknown. We sought to establish current practice in the United Kingdom (UK) including choice of mucolytic, dose, and frequency of utilisation. Methods.
Aarjan Peter Snoek, Joe Brierley
doaj +1 more source
Медицинский совет, 2018 The article is devoted to the use of mucolytic therapy in the treatment of infectious and inflammatory diseases of the respiratory tract. Pathogen exposure results in an increase in the viscosity and adhesion of the respiratory tract mucus and leads to ...
A. A. Krivopalov, P. A. Shamkina
doaj +1 more source