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Mucosal barrier and immune mediators
Current Opinion in Gastroenterology, 2001The intestinal mucosa functions is an immunologic organ that plays a major role in the development of oral tolerance and host-defense mechanisms. Antigens must cross the intestinal epithelium in a controlled manner to interact with dendritic antigen-presenting cells, because bacteria or their products are a primary risk factor for the development of ...
T, Sakaguchi, S, Brand, H C, Reinecker
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Digestion, 1972
The gastric mucosal barrier was a topic studied by many physiologists and clinicians in the 1960s and 1970s. I began my own work on it in early 1963, and when I stopped in the early 1980s I summarized my accomplishments in a book called The Gastric Mucosal Barrier: A Swan Song.
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The gastric mucosal barrier was a topic studied by many physiologists and clinicians in the 1960s and 1970s. I began my own work on it in early 1963, and when I stopped in the early 1980s I summarized my accomplishments in a book called The Gastric Mucosal Barrier: A Swan Song.
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The gastric mucosal barrier and ulceration
Brain Research Bulletin, 1980The gastric mucosal barrier is that property which defends against acid and which impedes diffusion of acid from the lumen into the mucosa. The disappearance of luminal H+ is linearly related to luminal (H+) both in the normal stomach and in stomachs exposed to barrier breakers. The latter invaribaly produce anatomic evidence of surface cellular injury.
W, Silen, R, Schiessel, E, Kivilaakso
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Probiotics and mucosal barrier in children
Current Opinion in Clinical Nutrition & Metabolic Care, 2008Colonization by the microbiota plays an important role in intestinal tract maturation of newborn. Once installed, indigenous microbiota maintains this modulation and also protects against infectious aggression. Due to these abilities, gut microbiota can be considered a 'microbial organ' that contributes to health of human host.
Francisco J, Penna +3 more
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Intestinal Inflammation and Mucosal Barrier Function
Inflammatory Bowel Diseases, 2014Intestinal mucosal barrier function is the capacity of the intestine to provide adequate containment of luminal microorganisms and molecules while preserving the ability to absorb nutrients. The central element is the epithelial layer, which physically separates the lumen and the internal milieu and is in charge of vectorial transport of ions ...
Fermín, Sánchez de Medina +3 more
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Development Of The Gastrointestinal Mucosal Barrier
Nutrition Reviews, 2009In young rabbits, advancing age and natural feeding promote the development of an efficient mucosal barrier capable of protecting the host's circulation from penetration by potentially antigenic macromolecules.
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Gastric Mucosal Barrier, Helicobacter pylori
2020Gastric mucosal barrier: The mucous neck and pit cells in the gastric mucosa produce mucin and bicarbonate which forms a “neutral zone” to protect the stomach lining. This bicarbonate rich mucus layer functions as a physical barrier to protect the stomach lining from the corrosive gastric hydrochloric acid secreted from the parietal cells of the ...
Hwee Ming Cheng +2 more
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HIV infection and the intestinal mucosal barrier
Annals of the New York Academy of Sciences, 2012HIV infection induces a barrier defect of the intestinal mucosa, which is closely linked to immune activation and CD4 T cell depletion. The HIV‐induced barrier defect is initiated in early acute and maintained through chronic infection. In acute infection, increased epithelial permeability is associated with increased epithelial apoptosis possibly ...
Hans-Jörg, Epple, Martin, Zeitz
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Mucosal Barrier Injury and Infections
2011Neutropenia is well known as a risk factor for infectious complications of patients treated for hematological malignancies. Less is known about the impact of intensive chemotherapy on the epithelial innate immunity that protects us from infections due to opportunistic pathogens that reside on the mucosal surfaces. Injury to the mucosal barrier leads to
Nicole M. A. Blijlevens +1 more
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Heartburn and Mucosal Barrier Weakness
1988Most of the patients who suffer from illness of the digestive tract do not show any signs of lesion after a careful examination. They are classified as “dyspentic” or of “psychosomatic” patients; many cases seem to have a functional disorder somewhere in the digestive tract.
J. J. Bernier, Ch. Florent
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