Acquisition of pneumococci specific effector and regulatory Cd4+ T cells localising within human upper respiratory-tract mucosal lymphoid tissue [PDF]
The upper respiratory tract mucosa is the location for commensal Streptococcus (S.) pneumoniae colonization and therefore represents a major site of contact between host and bacteria.
Mitchell, T.J. +28 more
core +1 more source
Alveolar Macrophages: Adaptation to Their Anatomic Niche during and after Inflammation
At the early stages of life development, alveoli are colonized by embryonic macrophages, which become resident alveolar macrophages (ResAM) and self-sustain by local division.
Florian Pierre Martin +3 more
doaj +1 more source
Microbiota and Mucosal Immunity in Amphibians [PDF]
We know that animals live in a world dominated by bacteria. In the last 20 years, we have learned that microbes are essential regulators of mucosal immunity. Bacteria, archeas, and viruses influence different aspects of mucosal development and function. Yet, the literature mainly covers findings obtained in mammals.
Bruno M Colombo +4 more
openaire +4 more sources
Mucosal Application of gp140 Encoding DNA Polyplexes to Different Tissues Results in Altered Immunological Outcomes in Mice [PDF]
25.03.14 KB.
Paul F McKay +34 more
core +2 more sources
BACKGROUND: Gastric variceal bleeding is associated with significant morbidity and mortality in patients with portal hypertension. Outside of North America, gastric variceal injection of N-butyl-2-cyanoacrylate has been shown to be safe and effective ...
PJ Belletrutti +6 more
doaj +1 more source
Blau syndrome NOD2 mutations result in loss of NOD2 cross-regulatory function
The studies described here provide an analysis of the pathogenesis of Blau syndrome and thereby the function of NOD2 as seen through the lens of its dysfunction resulting from Blau-associated NOD2 mutations in its nucleotide-binding domain (NBD). As such,
Liming Mao +11 more
doaj +1 more source
Rational design of HIV vaccine and microbicides: report of the EUROPRISE annual conference. [PDF]
EUROPRISE is a Network of Excellence sponsored from 2007 to 2011 by the European Commission within the 6th Framework Program. The Network encompasses a wide portfolio of activities ranging from an integrated research program in the field of HIV vaccines ...
Palma, Paolo +119 more
core +2 more sources
Age-Stratified T Cell Responses in Children Infected with Mycobacterium tuberculosis
Tuberculosis (TB) in young children differs from adult TB in that the risk of rapid progression to active TB (aTB) is higher in children than in adults. The reasons for this increased risk are not fully understood. Early differentiation remains difficult
Alexandra Dreesman +15 more
doaj +1 more source
Mucosal immunity to poliovirus
The Global Polio Eradication Initiative (GPEI) currently based on use of oral poliovirus vaccine (OPV) has identified suboptimal immunogenicity of this vaccine as a major impediment to eradication, with a failure to induce protection against paralytic poliomyelitis in certain population segments in some parts of the world.
Pearay L, Ogra +3 more
openaire +2 more sources
Editorial: Mucosal immunity after vaccination. [PDF]
The mucosal immune system is the largest immunological interface with the environment in our body. On the one hand, it contributes to the preservation of commensal microbiota by several mechanisms such production of secretory immunoglobulins, maintenance
Arish M, López-Siles M, Naz F.
europepmc +2 more sources

