Results 31 to 40 of about 244,081 (296)

Monoclonal antibody against EV71 3Dpol inhibits the polymerase activity of RdRp and virus replication

open access: yesBMC Immunology, 2019
Background Enterovirus A 71 (EV71) is a neurotropic virus that may lead to acute flaccid paralysis, encephalitis, cardiopulmonary failure or even death. No vaccine and defensive drug controlling EV71 is currently available, novel and efficient antiviral ...
Yaoming Li   +3 more
doaj   +1 more source

Enrichment of innate lymphoid cell populations in gingival tissue [PDF]

open access: yes, 2018
Innate lymphoid cells (ILCs) are a population of lymphocytes that act as the first line of immunologic defense at mucosal surfaces. The ILC family in the skin, lungs, and gastrointestinal tissues has been investigated, and there are reports of individual
Adrados Planell, A.   +5 more
core   +2 more sources

Transition metal ions at the crossroads of mucosal immunity and microbial pathogenesis. [PDF]

open access: yes, 2014
Transition metal ions are essential micronutrients for all living organisms. In mammals, these ions are often protein-bound and sequestered within cells, limiting their availability to microbes. Moreover, in response to infection, mammalian hosts further
Diaz-Ochoa, Vladimir E   +3 more
core   +2 more sources

Alveolar Macrophages: Adaptation to Their Anatomic Niche during and after Inflammation

open access: yesCells, 2021
At the early stages of life development, alveoli are colonized by embryonic macrophages, which become resident alveolar macrophages (ResAM) and self-sustain by local division.
Florian Pierre Martin   +3 more
doaj   +1 more source

TLR1-induced chemokine production is critical for mucosal immunity against Yersinia enterocolitica. [PDF]

open access: yes, 2013
Our gastrointestinal tract is a portal of entry for a number of bacteria and viruses. Thus, this tissue must develop ways to induce antigen-specific T cell and antibody responses quickly.
DePaolo, R William   +5 more
core   +1 more source

Mucosal immunity to poliovirus [PDF]

open access: yesMucosal Immunology, 2022
A cornerstone of the global initiative to eradicate polio is the widespread use of live and inactivated poliovirus vaccines in extensive public health campaigns designed to prevent the development of paralytic disease and interrupt transmission of the virus.
Connor, Ruth I   +7 more
openaire   +3 more sources

Nasal IgA Provides Protection against Human Influenza Challenge in Volunteers with Low Serum Influenza Antibody Titre

open access: yesFrontiers in Microbiology, 2017
In spite of there being a number of vaccines, influenza remains a significant global cause of morbidity and mortality. Understanding more about natural and vaccine induced immune protection against influenza infection would help to develop better ...
Victoria M. W. Gould   +5 more
doaj   +1 more source

Blau syndrome NOD2 mutations result in loss of NOD2 cross-regulatory function

open access: yesFrontiers in Immunology, 2022
The studies described here provide an analysis of the pathogenesis of Blau syndrome and thereby the function of NOD2 as seen through the lens of its dysfunction resulting from Blau-associated NOD2 mutations in its nucleotide-binding domain (NBD). As such,
Liming Mao   +11 more
doaj   +1 more source

Mucosal immune responses following intestinal nematode infection. [PDF]

open access: yes, 2014
In most natural environments, the large majority of mammals harbour parasitic helminths that often live as adults within the intestine for prolonged periods (1-2 years).
Else KJ   +11 more
core   +4 more sources

Effects of date palm fruit extracts on skin mucosal immunity, immune related genes expression and growth performance of common carp (Cyprinus carpio) fry [PDF]

open access: yes, 2015
The aim of this study was to investigate the effects of date palm fruit extracts (DPFE) on skin mucosal immunity, immune related genes expression and growth performance of fry common carp (Cyprinus carpio). One hundred and twenty specimens (4.06 ± 0.13 g)
Attar, M.   +6 more
core   +1 more source

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