Background: Human memory B cells play a vital role in the long-term protection of the host from pathogenic re-challenge. In recent years the importance of a number of different memory B cell subsets that can be formed in response to vaccination or ...
Luke Muir +7 more
doaj +1 more source
The Human Penis Is a Genuine Immunological Effector Site
The human penis is a main portal of entry for numerous pathogens, and vaccines able to control resulting infections locally are highly desirable. However, in contrast to the gastrointestinal or vaginal mucosa, the penile immune system and mechanisms ...
Alexis Sennepin +20 more
doaj +1 more source
Streptococcal Serine-Rich Repeat Proteins in Colonization and Disease
Glycosylation of proteins, previously thought to be absent in prokaryotes, is increasingly recognized as important for both bacterial colonization and pathogenesis.
Jia Mun Chan +3 more
doaj +1 more source
Immunogens and Antigen Processing: Report from a Global HIV Vaccine Enterprise Working Group [PDF]
The Global HIV Vaccine Enterprise convened a meeting of a Working Group in July 2009 to discuss recent progress in rational design of the components of an HIV vaccine, such as inserts, vectors and adjuvants,and in understanding antigen processing and ...
John Mascola +3 more
core +3 more sources
Experimental Models of Inflammatory Bowel DiseasesSummary
The understanding of the intestinal inflammation occurring in the inflammatory bowel diseases (IBD) has been immeasurably advanced by the development of the now numerous murine models of intestinal inflammation.
Patricia Kiesler +2 more
doaj +1 more source
To respond or not to respond - a personal perspective of intestinal tolerance [PDF]
For many years, the intestine was one of the poor relations of the immunology world, being a realm inhabited mostly by specialists and those interested in unusual phenomena.
A Besredka +142 more
core +1 more source
Role of lactobacilli and lactoferrin in the mucosal cervicovaginal defense [PDF]
Human lactoferrin is an iron-binding glycoprotein present at high concentrations in breast milk and colostrum. It is produced by many exocrine glands and widely distributed in a variety of body fluids.
Aagaard +156 more
core +5 more sources
Background Patients with end-stage renal disease undergoing chronic hemodialysis (HD) are at high risk to develop tuberculosis (TB) associated with a high mortality rate.
Florence Bonkain +6 more
doaj +1 more source
Immunological relationships during primary infection with Heligmosomoides polygyrus (Nematospiroides dubius): downregulation of specific cytokine secretion (IL-9 and IL-10) correlates with poor mastocytosis and chronic survival of adult worms [PDF]
Mice were infected either with Trichinella spiralis (day 0), Heligmosomoides polygyrus (day -14) or concurrently with both species and were killed in groups, together with naive control mice, on 2 occasions (day 8 and 15 post infection with T.
Behnke, Jerzy M. +5 more
core +2 more sources
MAIT cells come to the rescue in cancer immunotherapy? [PDF]
Recent progress in immunobiology has led to the observation that, among cells classically categorized as the typical representatives of the adaptive immune system, i.e., T cells, some possess the phenotype of innate cells.
Elewaut, Dirk +2 more
core +2 more sources

