Results 21 to 30 of about 5,761 (217)
Airway Mycobiota-Microbiota During Pulmonary Exacerbation of Cystic Fibrosis Patients: A Culture and Targeted Sequencing Study. [PDF]
ABSTRACT Background The airways of patients with cystic fibrosis (pwCF) harbour complex fungal and bacterial microbiota involved in pulmonary exacerbations (PEx) and requiring antimicrobial treatment. Descriptive studies analysing bacterial and fungal microbiota concomitantly are scarce, especially using both culture and high‐throughput‐sequencing (HTS)
Angebault C +11 more
europepmc +2 more sources
Quality of care in cystic fibrosis: assessment protocol of the French QIP PHARE-M
Background The PHARE-M care quality improvement program, modeled on the US Cystic Fibrosis Quality Improvement Program, was introduced at 14 cystic fibrosis centers (CFCs) in the French Cystic Fibrosis Network between 2011 and 2013.
Dominique Pougheon Bertrand +4 more
doaj +1 more source
Therapeutic Approaches for Patients with Cystic Fibrosis Not Eligible for Current CFTR Modulators
Cystic fibrosis is a severe autosomal recessive disorder caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene encoding the CFTR protein, a chloride channel expressed in many epithelial cells.
Isabelle Fajac, Isabelle Sermet
doaj +1 more source
Introduction Chronic lung allograft dysfunction (CLAD) can take two forms: bronchiolitis obliterans syndrome (BOS) or restrictive allograft syndrome (RAS).
Paul Habert +8 more
doaj +1 more source
In vitroprediction of stop-codon suppression by intravenous gentamicin in patients with cystic fibrosis: a pilot study [PDF]
Background Cystic fibrosis (CF) is caused by mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR) protein, which acts as a chloride channel activated by cyclic AMP (cAMP).
Isabelle Sermet-Gaudelus +12 more
core +2 more sources
Introdução: A Fibrose Cística (FC) é uma anormalidade genética de caráter sistêmico gerando ao sistema respiratório uma hipersecretividade e obstrução brônquica crônica.
Francisco Oliveira +5 more
doaj +1 more source
Introduction: Cystic fibrosis (CF) is caused by defective Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) proteins. CFTR controls chloride (Cl−) and bicarbonate (HCO3−) transport into the Airway Surface Liquid (ASL). We investigated the impact
Miroslaw Zajac +37 more
doaj +1 more source
Diagnostic prénatal et diagnostic pré-implantatoire : arbre décisionnel, nouvelles pratiques ? [PDF]
Le diagnostic pré-implantatoire (DPI) a pour objectif l’étude des caractéristiques génétiques d’un embryon âgé de trois jours. Il offre ainsi à des couples ayant un risque élevé de transmettre une maladie héréditaire une alternative au diagnostic ...
Feyereisen, Estelle +4 more
core +1 more source
De l'animal expérimental au modèle en recherche biomédicale. [PDF]
Cet article est destiné à la Revue PhilosophiqueSince the beginning of experimentation in biology, animals have been used to study processes that cannot be approached on human beings.
Gachelin, Gabriel
core +3 more sources
Role of Host and Bacterial Lipids in Pseudomonas aeruginosa Respiratory Infections
The opportunistic pathogen Pseudomonas aeruginosa is one of the most common agents of respiratory infections and has been associated with high morbidity and mortality rates. The ability of P. aeruginosa to cause severe respiratory infections results from
Pamella Constantino-Teles +3 more
doaj +1 more source

